AU2001280436A1 - Process to increase protein stability - Google Patents

Process to increase protein stability

Info

Publication number
AU2001280436A1
AU2001280436A1 AU2001280436A AU8043601A AU2001280436A1 AU 2001280436 A1 AU2001280436 A1 AU 2001280436A1 AU 2001280436 A AU2001280436 A AU 2001280436A AU 8043601 A AU8043601 A AU 8043601A AU 2001280436 A1 AU2001280436 A1 AU 2001280436A1
Authority
AU
Australia
Prior art keywords
protein stability
increase protein
increase
stability
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001280436A
Inventor
Thomas Charles Furman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU2001280436A1 publication Critical patent/AU2001280436A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001280436A 2000-07-12 2001-06-29 Process to increase protein stability Abandoned AU2001280436A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21757800P 2000-07-12 2000-07-12
US60/217,578 2000-07-12
PCT/US2001/016510 WO2002004481A2 (en) 2000-07-12 2001-06-29 Process to increase protein stability

Publications (1)

Publication Number Publication Date
AU2001280436A1 true AU2001280436A1 (en) 2002-01-21

Family

ID=22811643

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001280436A Abandoned AU2001280436A1 (en) 2000-07-12 2001-06-29 Process to increase protein stability

Country Status (4)

Country Link
US (1) US20030212248A1 (en)
EP (1) EP1303532A2 (en)
AU (1) AU2001280436A1 (en)
WO (1) WO2002004481A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1881323B1 (en) * 2005-05-11 2011-07-27 Yamasa Corporation Method of stabilizing pulmonary surfactant protein
CA2740685C (en) 2008-10-17 2018-09-11 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
US9052323B2 (en) * 2009-08-27 2015-06-09 The University Of Kansas Osmolyte mixture for protein stabilization
CN104672297A (en) * 2013-12-03 2015-06-03 内蒙古农业大学 Screening method of optimal condition for preparing amino-containing micro-molecular substance and protein conjugate based on EDC reaction
TWI748945B (en) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 Treatment type 2 diabetes mellitus patients
TW201705975A (en) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 Treatment of type 2 diabetes mellitus patients
US11447547B1 (en) 2017-12-13 2022-09-20 Amgen Inc. Method of antigen-binding protein production
CN111493207B (en) * 2020-04-21 2023-05-12 无锡金农生物科技有限公司 Preparation method of modified rice protein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3695467B2 (en) * 1993-02-04 2005-09-14 ボレアン ファーマ エー／エス Improved method for regenerating proteins
JP2002514890A (en) * 1995-06-07 2002-05-21 カイロン コーポレイション Methods for purifying authentic IGF from yeast hosts
DE19735711C2 (en) * 1997-08-18 2001-04-26 Aventis Pharma Gmbh Process for the preparation of a precursor to insulin or insulin derivatives with correctly linked cystine bridges

Also Published As

Publication number Publication date
US20030212248A1 (en) 2003-11-13
EP1303532A2 (en) 2003-04-23
WO2002004481A2 (en) 2002-01-17
WO2002004481A3 (en) 2002-09-26

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