AU2001276934A1 - Methods of modulating fibrosis - Google Patents
Methods of modulating fibrosisInfo
- Publication number
- AU2001276934A1 AU2001276934A1 AU2001276934A AU7693401A AU2001276934A1 AU 2001276934 A1 AU2001276934 A1 AU 2001276934A1 AU 2001276934 A AU2001276934 A AU 2001276934A AU 7693401 A AU7693401 A AU 7693401A AU 2001276934 A1 AU2001276934 A1 AU 2001276934A1
- Authority
- AU
- Australia
- Prior art keywords
- methods
- modulating fibrosis
- fibrosis
- modulating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21924400P | 2000-07-18 | 2000-07-18 | |
US60219244 | 2000-07-18 | ||
PCT/US2001/022347 WO2002007747A1 (en) | 2000-07-18 | 2001-07-17 | Methods of modulating fibrosis |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001276934A1 true AU2001276934A1 (en) | 2002-02-05 |
Family
ID=22818479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001276934A Abandoned AU2001276934A1 (en) | 2000-07-18 | 2001-07-17 | Methods of modulating fibrosis |
Country Status (4)
Country | Link |
---|---|
US (1) | US7175844B2 (en) |
EP (1) | EP1311277A4 (en) |
AU (1) | AU2001276934A1 (en) |
WO (1) | WO2002007747A1 (en) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
IL144144A0 (en) | 1999-01-13 | 2002-05-23 | Bayer Ag | Omega-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
EP2279757A3 (en) | 2000-06-02 | 2011-08-03 | Bracco Suisse SA | Compounds for targeting endothelial cells |
US8263739B2 (en) | 2000-06-02 | 2012-09-11 | Bracco Suisse Sa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
CA2417960C (en) | 2000-08-04 | 2012-07-10 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
EP1386004A4 (en) | 2001-04-05 | 2005-02-16 | Ribozyme Pharm Inc | Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies |
CA2526831C (en) * | 2001-05-18 | 2012-07-31 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina) |
US9994853B2 (en) | 2001-05-18 | 2018-06-12 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
ATE526041T1 (en) * | 2001-12-11 | 2011-10-15 | Fibrogen Inc | METHOD FOR INHIBITING OCCULAR PROCESSES |
PT1478358E (en) | 2002-02-11 | 2013-09-11 | Bayer Healthcare Llc | Sorafenib tosylate for the treatment of diseases characterized by abnormal angiogenesis |
US9181551B2 (en) | 2002-02-20 | 2015-11-10 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
AU2003207708A1 (en) * | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
US9657294B2 (en) | 2002-02-20 | 2017-05-23 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
US7985402B2 (en) * | 2002-03-01 | 2011-07-26 | Bracco Suisse Sa | Targeting vector-phospholipid conjugates |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US20050250700A1 (en) * | 2002-03-01 | 2005-11-10 | Sato Aaron K | KDR and VEGF/KDR binding peptides |
US7261876B2 (en) * | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
AU2003278807A1 (en) * | 2002-03-01 | 2004-08-13 | Bracco International B.V. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
US7666979B2 (en) * | 2002-03-01 | 2010-02-23 | Bracco International B.V. | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same |
US7211240B2 (en) * | 2002-03-01 | 2007-05-01 | Bracco International B.V. | Multivalent constructs for therapeutic and diagnostic applications |
WO2004075917A1 (en) * | 2003-02-28 | 2004-09-10 | Toudai Tlo, Ltd. | Organ or tissue fibrosis inhibitor |
HUE039154T2 (en) | 2003-03-03 | 2018-12-28 | Dyax Corp | Peptides that specifically bind HGF receptor (cMet) and uses thereof |
CN103191410B (en) | 2003-05-15 | 2015-03-04 | 安皮奥制药股份有限公司 | Treatment of T-cell mediated diseases |
ATE366108T1 (en) | 2003-05-20 | 2007-07-15 | Bayer Pharmaceuticals Corp | DIARYL UREAS FOR PDGFR-MEDIATED DISEASES |
AU2005212433B2 (en) | 2003-05-23 | 2010-12-16 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional sINA) |
PL1663978T3 (en) | 2003-07-23 | 2008-04-30 | Bayer Healthcare Llc | Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions |
AU2005244154C1 (en) * | 2004-04-28 | 2010-07-01 | Fibrogen, Inc. | Treatments for pancreatic cancer |
MXPA06012394A (en) | 2004-04-30 | 2007-01-31 | Bayer Pharmaceuticals Corp | Substituted pyrazolyl urea derivatives useful in the treatment of cancer. |
US10508277B2 (en) | 2004-05-24 | 2019-12-17 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
EP1809364A4 (en) * | 2004-11-12 | 2010-06-16 | Univ Minnesota | A veinous occlusion device and methods of using |
US20060154939A1 (en) * | 2004-12-24 | 2006-07-13 | Boehringer Ingelheim International Gmbh | Medicaments for the Treatment or Prevention of Fibrotic Diseases |
US20070102622A1 (en) * | 2005-07-01 | 2007-05-10 | Olsen Richard I | Apparatus for multiple camera devices and method of operating same |
US8735178B2 (en) * | 2006-03-27 | 2014-05-27 | University Of Kentucky Research Foundation | Withanolides, probes and binding targets and methods of use thereof |
EP2121681B1 (en) | 2007-01-11 | 2015-04-15 | Critical Outcome Technologies, Inc. | Compounds and method for treatment of cancer |
US8501789B2 (en) * | 2007-01-19 | 2013-08-06 | The Trustees Of The University Of Pennsylvania | Use of salicylaldehyde isonicotinoyl hydrazone (SIH) for protection against retinal disease |
EP2225226B1 (en) * | 2007-12-26 | 2016-08-17 | Critical Outcome Technologies, Inc. | Compounds and their use in a method for treatment of cancer |
AU2009207923A1 (en) * | 2008-01-23 | 2009-07-30 | Rigshospitalet | Classification of individuals suffering from cardiovascular diseases according to survival prognoses as found by measuring the levels of biomarker YKL-40 |
WO2009146320A1 (en) | 2008-05-27 | 2009-12-03 | Dmi Life Sciences, Inc. | Therapeutic methods and compounds |
EP2318406B1 (en) | 2008-07-17 | 2016-01-27 | Critical Outcome Technologies, Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
AU2009293658A1 (en) | 2008-09-22 | 2010-03-25 | James Cardia | Reduced size self-delivering RNAi compounds |
EP2550001B1 (en) | 2010-03-24 | 2019-05-22 | Phio Pharmaceuticals Corp. | Rna interference in ocular indications |
CN103108642B (en) | 2010-03-24 | 2015-09-23 | 雷克西制药公司 | RNA in skin and fibrotic conditions disturbs |
EP2550000A4 (en) | 2010-03-24 | 2014-03-26 | Advirna Inc | Reduced size self-delivering rnai compounds |
EP3235818A3 (en) | 2010-04-01 | 2018-03-14 | Critical Outcome Technologies, Inc. | Compounds for the treatment of hiv |
WO2012033792A2 (en) | 2010-09-07 | 2012-03-15 | Dmi Acquisition Corp. | Treatment of diseases |
US9260471B2 (en) | 2010-10-29 | 2016-02-16 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA) |
BR112014007675A2 (en) | 2011-10-10 | 2017-04-18 | Ampio Pharmaceuticals Inc | degenerative joint disease treatment |
MY172699A (en) | 2011-10-10 | 2019-12-10 | Ampio Pharmaceuticals Inc | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
WO2013063413A1 (en) | 2011-10-28 | 2013-05-02 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
JP6069356B2 (en) * | 2012-01-05 | 2017-02-01 | クラノテク・アクチボラグ | Quinoline compounds that are anti-angiogenic integrin α5β1 inhibitors for use in the treatment of fibrosis or fibrosis related diseases |
CA2906864A1 (en) | 2013-03-15 | 2014-09-18 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
EP3104845A4 (en) * | 2014-02-10 | 2017-09-27 | Salk Institute for Biological Studies | Increasing storage of vitamin a, vitamin d and/or lipids |
RU2020136589A (en) | 2014-08-18 | 2020-12-24 | Ампио Фармасьютикалз, Инк. | TREATMENT OF DEGENERATIVE JOINT DISEASES |
EP3310375A4 (en) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | Use of low molecular weight fractions of human serum albumin in treating diseases |
CA3053392A1 (en) * | 2017-02-28 | 2018-09-07 | The Board Of Trustees Of The Leland Stanford Junior University | Antifibrotic activity of cd47 blockade |
TW202108606A (en) | 2019-05-03 | 2021-03-01 | 新加坡商新加坡保健服務私人有限公司 | Treatment and prevention of metabolic diseases |
WO2021141733A1 (en) | 2020-01-07 | 2021-07-15 | The Procter & Gamble Company | Method of modulating a fibrotic condition |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK285035B6 (en) * | 1992-10-28 | 2006-05-04 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
US6410322B1 (en) * | 1993-07-27 | 2002-06-25 | Hybridon Inc | Antisense oligonucleotide inhibition of vascular endothelial growth factor expression |
US6734285B2 (en) * | 1994-03-08 | 2004-05-11 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 proteins and compositions |
US6001622A (en) * | 1995-12-21 | 1999-12-14 | Sunnybrook Health Science Centre | Integrin-linked kinase and its use |
WO1997034920A1 (en) | 1996-03-21 | 1997-09-25 | Sugen, Inc. | Assays for kdr/flk-1 receptor tyrosine kinase inhibitors |
ATE405651T1 (en) * | 1998-03-17 | 2008-09-15 | Genentech Inc | POLYPEPTIDES HOMOLOGUE TO VEGF AND BMP1 |
US6100090A (en) | 1999-06-25 | 2000-08-08 | Isis Pharmaceuticals Inc. | Antisense inhibition of PI3K p85 expression |
ATE485834T1 (en) * | 1998-09-08 | 2010-11-15 | Ford Henry Health System | METHOD FOR DETECTING CONNECTIVE TISSUE GROWTH FACTOR FOR DIAGNOSING KIDNEY DISEASES |
-
2001
- 2001-07-17 US US09/907,045 patent/US7175844B2/en not_active Expired - Fee Related
- 2001-07-17 AU AU2001276934A patent/AU2001276934A1/en not_active Abandoned
- 2001-07-17 EP EP01954706A patent/EP1311277A4/en not_active Withdrawn
- 2001-07-17 WO PCT/US2001/022347 patent/WO2002007747A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
EP1311277A4 (en) | 2004-08-25 |
WO2002007747A1 (en) | 2002-01-31 |
US20020086013A1 (en) | 2002-07-04 |
US7175844B2 (en) | 2007-02-13 |
EP1311277A1 (en) | 2003-05-21 |
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