AU2001274146A1 - Biocompatible polymer for fixing biological ligands - Google Patents

Biocompatible polymer for fixing biological ligands

Info

Publication number
AU2001274146A1
AU2001274146A1 AU2001274146A AU7414601A AU2001274146A1 AU 2001274146 A1 AU2001274146 A1 AU 2001274146A1 AU 2001274146 A AU2001274146 A AU 2001274146A AU 7414601 A AU7414601 A AU 7414601A AU 2001274146 A1 AU2001274146 A1 AU 2001274146A1
Authority
AU
Australia
Prior art keywords
polymer
mole
monomer
biocompatible polymer
biological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001274146A
Inventor
Marie-Therese Charreyre
Franck D'agosto
Arnaud Favier
Bernard Mandrand
Christian Pichot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA filed Critical Biomerieux SA
Publication of AU2001274146A1 publication Critical patent/AU2001274146A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Peptides Or Proteins (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

The invention concerns a biocompatible polymer having a mole weight more than 50000 g/mole, preferably 90000 g/mole for fixing biological ligands comprising at least a first linear segment consisting of a hydrophobic homopolymer derived from polymerisation of a hydrophobic monomer A; a second linear segment consisting of a hydrophilic polymer derived from copolymerisation of a monomer B bearing a reactive function X and a hydrophilic monomer C not bearing any reactive function, said second segment being covalently bound to one end of the first segment. The invention also concerns a biological polymer-ligand-conjugate, a device for capturing a target molecule comprising a solid support whereon is immobilised a biological polymer-ligand conjugate and methods for preparing said polymer. The invention is mainly applicable in the field of diagnosis.
AU2001274146A 2000-05-29 2001-05-29 Biocompatible polymer for fixing biological ligands Abandoned AU2001274146A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0006861 2000-05-29
FR0006861 2000-05-29
PCT/FR2001/001663 WO2001092361A1 (en) 2000-05-29 2001-05-29 Biocompatible polymer for fixing biological ligands

Publications (1)

Publication Number Publication Date
AU2001274146A1 true AU2001274146A1 (en) 2001-12-11

Family

ID=8850740

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001274146A Abandoned AU2001274146A1 (en) 2000-05-29 2001-05-29 Biocompatible polymer for fixing biological ligands

Country Status (7)

Country Link
US (1) US20040091451A1 (en)
EP (1) EP1290052B1 (en)
AT (1) ATE325144T1 (en)
AU (1) AU2001274146A1 (en)
DE (1) DE60119318T2 (en)
ES (1) ES2262653T3 (en)
WO (1) WO2001092361A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020063098A (en) * 2001-01-26 2002-08-01 히다찌 플랜트 겐세쓰 가부시키가이샤 Method for removing hormone disrupting chemicals from water
US7338805B2 (en) 2001-05-04 2008-03-04 Bio Merieux Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules
US7060441B2 (en) 2001-05-04 2006-06-13 Biomerieux Method for fragmenting and labeling DNA involving abasic sites and phosphate labeling
MXPA04006145A (en) * 2001-12-21 2005-03-31 Univ Sydney Aqueous dispersions of polymer particles.
ES2291613T3 (en) 2002-01-16 2008-03-01 Biocompatibles Uk Limited CONJUGATES OF POLYMERS.
FR2848556B1 (en) * 2002-12-13 2006-06-16 Bio Merieux CONTROLLED RADICAL POLYMERIZATION PROCESS
GB0301014D0 (en) * 2003-01-16 2003-02-19 Biocompatibles Ltd Conjugation reactions
FR2868071B1 (en) * 2004-03-26 2006-06-09 Biomerieux Sa MARKING REAGENTS, METHODS FOR SYNTHESIZING SUCH REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES
ES2249190B2 (en) * 2005-05-13 2006-10-01 Ametsis, Ingenieria Y Asesoria Tecnica, S.L. DEVELOPMENT CONTROL SYSTEM.
FR2886735B1 (en) 2005-06-01 2015-09-11 Biomerieux Sa PROCESS FOR MARKING OR PROCESSING A BIOLOGICAL SAMPLE CONTAINING BIOLOGICAL MOLECULES OF INTEREST, IN PARTICULAR NUCLEIC ACIDS
US20070155907A1 (en) * 2005-12-30 2007-07-05 Zhao Jonathon Z Biologically active block copolymers
FR2917090B1 (en) * 2007-06-11 2012-06-15 Biomerieux Sa MARKING REAGENTS HAVING DIAZO AND NITRO FUNCTIONS, METHODS FOR SYNTHESIZING SUCH REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES
FR2934595B1 (en) * 2008-07-29 2013-04-05 Biomerieux Sa MARKING REAGENTS HAVING A PYRIDINE CORE HAVING DIAZOMETHYL FUNCTION, METHODS FOR SYNTHESIZING SUCH REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES
IT1398097B1 (en) * 2010-02-19 2013-02-07 Università Di Pisa METHOD FOR THE PRODUCTION OF MINIATURIZED BIOSENSORS, AND BIOSENSORS OBTAINED WITH THIS METHOD
JP2020502226A (en) * 2016-12-23 2020-01-23 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション Biocompatible hydrophilic polymer conjugates for targeted drug delivery

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US5217492A (en) * 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
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US4724207A (en) * 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
GB2240547A (en) * 1990-01-31 1991-08-07 Ciba Geigy Ag New compositions
EP0538127A1 (en) * 1991-10-14 1993-04-21 Terumo Kabushiki Kaisha Medical materials having blood compatibility
EP0556649B1 (en) * 1992-02-20 1999-06-23 E.I. Du Pont De Nemours & Company Incorporated Aqueous dispersions containing ABC triblock polymer dispersants
FR2688788B1 (en) * 1992-03-17 1994-05-13 Bio Merieux WATER-SOLUBLE COMPOUNDS DERIVED FROM A HOMOPOLYMER OR COPOLYMER OF MALEIC ANHYDRIDE, AND APPLICATIONS OF SAID COMPOUNDS TO THE SUPPORT OF BIOLOGICAL MOLECULES
FR2707010B1 (en) * 1993-06-25 1995-09-29 Bio Merieux
FR2710075B1 (en) * 1993-09-15 1995-10-27 Bio Merieux Reagent and method for the detection of a nucleotide sequence with signal amplification.
AU682287B2 (en) * 1995-05-10 1997-09-25 Morton International, Inc. Latent mercaptans as multi-functional additives for halogen-containing polymer compositions
ATE342295T1 (en) * 1995-07-28 2006-11-15 Genzyme Corp BIODEGRADABLE MULTIBLOKHYDROGENS AND THEIR USE AS CARRIERS FOR CONTROLLED RELEASE PHARMACOLOGICALLY ACTIVE MATERIALS AND TISSUE CONTACT MATERIALS
WO1997049387A1 (en) * 1996-06-27 1997-12-31 G.D. Searle And Co. Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications
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US6077674A (en) * 1999-10-27 2000-06-20 Agilent Technologies Inc. Method of producing oligonucleotide arrays with features of high purity

Also Published As

Publication number Publication date
EP1290052A1 (en) 2003-03-12
DE60119318D1 (en) 2006-06-08
EP1290052B1 (en) 2006-05-03
DE60119318T2 (en) 2007-05-03
WO2001092361A1 (en) 2001-12-06
ES2262653T3 (en) 2006-12-01
ATE325144T1 (en) 2006-06-15
US20040091451A1 (en) 2004-05-13

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