AU2001272714A1 - Universal solid supports for solid phase oligosynthesis and methods for their preparation and use - Google Patents

Universal solid supports for solid phase oligosynthesis and methods for their preparation and use

Info

Publication number
AU2001272714A1
AU2001272714A1 AU2001272714A AU7271401A AU2001272714A1 AU 2001272714 A1 AU2001272714 A1 AU 2001272714A1 AU 2001272714 A AU2001272714 A AU 2001272714A AU 7271401 A AU7271401 A AU 7271401A AU 2001272714 A1 AU2001272714 A1 AU 2001272714A1
Authority
AU
Australia
Prior art keywords
preparation
methods
universal
solid phase
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001272714A
Inventor
Viktor Kumarev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proligo LLC
Original Assignee
Genset SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genset SA filed Critical Genset SA
Publication of AU2001272714A1 publication Critical patent/AU2001272714A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
AU2001272714A 2000-06-13 2001-06-12 Universal solid supports for solid phase oligosynthesis and methods for their preparation and use Abandoned AU2001272714A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21134400P 2000-06-13 2000-06-13
US60/211,344 2000-06-13
PCT/IB2001/001392 WO2001096357A2 (en) 2000-06-13 2001-06-12 Universal solid supports for solid phase oligosynthesis and methods for their preparation and use

Publications (1)

Publication Number Publication Date
AU2001272714A1 true AU2001272714A1 (en) 2001-12-24

Family

ID=22786535

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001272714A Abandoned AU2001272714A1 (en) 2000-06-13 2001-06-12 Universal solid supports for solid phase oligosynthesis and methods for their preparation and use

Country Status (5)

Country Link
US (1) US20040215010A1 (en)
EP (1) EP1289911A2 (en)
JP (1) JP2004503560A (en)
AU (1) AU2001272714A1 (en)
WO (1) WO2001096357A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7427678B2 (en) 1998-01-08 2008-09-23 Sigma-Aldrich Co. Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
US6426184B1 (en) 1998-02-11 2002-07-30 The Regents Of The University Of Michigan Method and apparatus for chemical and biochemical reactions using photo-generated reagents
US7211654B2 (en) 2001-03-14 2007-05-01 Regents Of The University Of Michigan Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports
AU2003210629A1 (en) 2002-01-23 2003-09-02 Proligo, Llc Methods for the integrated synthesis and purification of oligonucleotides
US7615629B2 (en) 2002-12-31 2009-11-10 Sigma-Aldrich Co. Methods and compositions for the tandem synthesis of two or more oligonucleotides on the same solid support
WO2009128982A2 (en) * 2008-04-18 2009-10-22 Saint-Gobain Abrasives, Inc. High porosity abrasive articles and methods of manufacturing same
WO2011059459A1 (en) * 2009-11-16 2011-05-19 Regado Biosciences, Inc Physical characterization of oligonucleotides conjugates
US20110117660A1 (en) * 2009-11-16 2011-05-19 Brooks Douglas G Physical characterization of oligonucleotide conjugates
EP3378869A4 (en) 2015-11-17 2019-09-18 Nissan Chemical Corporation Method for producing oligonucleotide

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4373071A (en) * 1981-04-30 1983-02-08 City Of Hope Research Institute Solid-phase synthesis of polynucleotides
US4948882A (en) * 1983-02-22 1990-08-14 Syngene, Inc. Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
US5362866A (en) * 1983-09-02 1994-11-08 Molecular Biosystems, Inc. Oligonucleotide polymeric support system with an oxidation cleavable link
US5539097A (en) * 1983-09-02 1996-07-23 Molecular Biosystems, Inc. Oligonucleotide polymeric support system
DE3500180A1 (en) * 1985-01-04 1986-07-10 Ernst Prof. Dr. 7400 Tübingen Bayer Graft copolymers from crosslinked polymers and polyoxyethylene, process for their preparation and their use
US4659774A (en) * 1985-11-01 1987-04-21 American Hoechst Corporation Support for solid-phase oligonucleotide synthesis
US5112962A (en) * 1989-04-19 1992-05-12 Northwestern University Labile anchors for solid phase polynucleotide synthesis
DK0464638T3 (en) * 1990-07-02 1997-10-13 Hoechst Ag Oligonucleotide analogs with terminal 3-3 or 5-5 internucleotide bonds.
US5235028A (en) * 1990-08-31 1993-08-10 University Of Minnesota Polyethylene glycol derivatives for solid-phase applications
GB9207380D0 (en) * 1992-04-03 1992-05-13 Ici Plc Compounds
FR2714061B1 (en) * 1993-12-16 1996-03-08 Genset Sa Process for the preparation of polynucleotides on solid support and apparatus allowing its implementation.
US5688940A (en) * 1996-02-01 1997-11-18 Biosearch Technologies, Inc. Linker for immobilization, modification and subsequent release of oligomers with a terminal hydroxyl group
US5869696A (en) * 1996-04-22 1999-02-09 Beckman Instruments, Inc. Universal solid supports and methods for their use

Also Published As

Publication number Publication date
WO2001096357A2 (en) 2001-12-20
EP1289911A2 (en) 2003-03-12
WO2001096357A3 (en) 2002-08-08
JP2004503560A (en) 2004-02-05
US20040215010A1 (en) 2004-10-28

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