AU2001269836A1 - Proteases - Google Patents

Proteases

Info

Publication number
AU2001269836A1
AU2001269836A1 AU2001269836A AU6983601A AU2001269836A1 AU 2001269836 A1 AU2001269836 A1 AU 2001269836A1 AU 2001269836 A AU2001269836 A AU 2001269836A AU 6983601 A AU6983601 A AU 6983601A AU 2001269836 A1 AU2001269836 A1 AU 2001269836A1
Authority
AU
Australia
Prior art keywords
proteases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001269836A
Other languages
English (en)
Inventor
Chandra S. Arvizu
Janice Au-Young
Yalda Azimzai
Mariah R. Baughn
Narinder K. Chawla
Debopriya Das
Angelo M Delegeane
Vicki S. Elliott
Ameena R. Gandhi
April Hafalia
Deborah A. Kallick
Liam Kearney
Farrah A. Khan
Preeti Lal
Ernestine A. Lee
Dyung Aina M. Lu
Yan Lu
Danniel B. Nguyen
Jayalaxmi Ramkumar
Roopa Reddy
Y. Tom Tang
Catherine M. Tribouley
Roderick T. Walsh
Yuming Xu
Monique G. Yao
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of AU2001269836A1 publication Critical patent/AU2001269836A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001269836A 2000-06-16 2001-06-13 Proteases Abandoned AU2001269836A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US21233600P 2000-06-16 2000-06-16
US60/212,336 2000-06-16
US21395500P 2000-06-22 2000-06-22
US60/213,955 2000-06-22
US21539600P 2000-06-29 2000-06-29
US60/215,396 2000-06-29
US21682100P 2000-07-07 2000-07-07
US60/216,821 2000-07-07
US21894600P 2000-07-14 2000-07-14
US60/218,946 2000-07-14
PCT/US2001/019178 WO2001098468A2 (fr) 2000-06-16 2001-06-13 Proteases

Publications (1)

Publication Number Publication Date
AU2001269836A1 true AU2001269836A1 (en) 2002-01-02

Family

ID=27539651

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001269836A Abandoned AU2001269836A1 (en) 2000-06-16 2001-06-13 Proteases

Country Status (5)

Country Link
EP (1) EP1292684A2 (fr)
JP (1) JP2004515217A (fr)
AU (1) AU2001269836A1 (fr)
CA (1) CA2411971A1 (fr)
WO (1) WO2001098468A2 (fr)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030096391A1 (en) * 2000-12-22 2003-05-22 Millennium Pharmaceuticals, Inc. 17903, a novel human aminopeptidase and uses therefor
US6716613B1 (en) * 1999-11-11 2004-04-06 Yamanouchi Pharmaceutical Co., Ltd. Metalloprotease having aggrecanase activity
US7700341B2 (en) 2000-02-03 2010-04-20 Dendreon Corporation Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
AU2001257594A1 (en) * 2000-04-18 2001-10-30 Millennium Pharmaceuticals, Inc. 21953, a novel human prolyl oligopeptidase family member and uses thereof
US20030083244A1 (en) * 2000-04-26 2003-05-01 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
EP1294901A2 (fr) * 2000-05-04 2003-03-26 Sugen, Inc. Nouvelles proteases
DK1297006T3 (da) * 2000-06-23 2006-05-22 Bayer Healthcare Ag Regulering af human prostasin-lignende serinprotease
EP1297154A2 (fr) * 2000-06-26 2003-04-02 Bayer Aktiengesellschaft Regulation de la protease de type caspase 1 humaine
WO2002006331A2 (fr) * 2000-07-18 2002-01-24 Millennium Pharmaceuticals, Inc. 14087, nouvelle molecule de serine protease, et utilisations associees
AU2001293718A1 (en) * 2000-08-07 2002-02-18 Bayer Aktiengesellschaft Regulation of human membrane-type serine protease
GB0020345D0 (en) * 2000-08-17 2000-10-04 Glaxo Group Ltd Protein
EP1311690B1 (fr) * 2000-08-22 2006-07-26 Lexicon Genetics Incorporated Proteases humaines et polynucleotides codant lesdites proteases
AU2002215312A1 (en) * 2000-09-29 2002-04-08 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
AU1313802A (en) * 2000-10-12 2002-04-22 Ferring Bv Novel serine protease genes related to dppiv
WO2002051995A1 (fr) * 2000-12-22 2002-07-04 Millennium Pharmaceuticals, Inc. Element metalloprotease humain de la famille adam, et utilisations de celui-ci
GB0101760D0 (en) * 2001-01-23 2001-03-07 Glaxo Group Ltd Novel protein
US7172892B2 (en) * 2001-03-22 2007-02-06 Dendreon Corporation Nucleic acid molecules encoding serine protease CVSP14, the encoded polypeptides and methods based thereon
US7034134B2 (en) * 2001-04-26 2006-04-25 Bristol-Myers Squibb Company Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
KR20040080940A (ko) * 2001-05-14 2004-09-20 덴드레온 코포레이션 트랜스막 세린 프로테아제 10을 암호화하는 핵산 분자,암호화된 폴리펩티드 및 이에 근거한 방법
AU2002319703A1 (en) 2001-07-27 2003-02-17 Wyeth Aggrecanase molecules
JP2003180384A (ja) * 2001-09-24 2003-07-02 Daiichi Fine Chemical Co Ltd Ａｄａｍｔｓ−１５，−１６，−１７，−１８及び−１９
AU2002351945A1 (en) * 2001-11-13 2003-05-26 Universite De Liege A new disintegrin and metalloproteinase with thrombospondin type i repeats polynucleotide and its encoded polypeptide
WO2003064651A2 (fr) * 2002-01-28 2003-08-07 Bayer Healthcare Ag Regulation de la serine protease humaine du type membrane
EP2341350B1 (fr) * 2003-09-20 2017-11-08 Electrophoretics Limited Methode de diagnostic de troubles associes a des lesions cerebrales basee sur la detection de dj-1
US20080248462A1 (en) * 2003-10-21 2008-10-09 Baayer Healhcare Ag Diagnostics and Therapeutics for Diseases Associated with Arginyl Aminopeptidase (Aminopeptidase B)-Like 1 (Rnpepl1)
WO2005106021A1 (fr) * 2004-04-28 2005-11-10 Bayer Healthcare Ag Diagnostics et therapeutique de maladies associees a la dipeptidyle peptidase 8 (dpp8)
EP1751182A1 (fr) * 2004-05-27 2007-02-14 VIB vzw Nouvelle proteine humaine presentant des homologies avec card inhibant la maturation de la pro-il-1beta
DK2032701T3 (da) * 2006-06-23 2014-02-10 Alethia Biotherapeutics Inc Polynukleotider og polypeptider, der er inddraget i cancer
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
AU2007322265B2 (en) 2006-11-07 2013-06-20 Merck Sharp & Dohme Corp. Antagonists of PCSK9
EP2142217B1 (fr) 2007-03-27 2014-11-05 Merck Sharp & Dohme Corp. Procédé de détection de pcsk9 secrétée, autogénérée
JOP20080381B1 (ar) 2007-08-23 2023-03-28 Amgen Inc بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
AR070316A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9)
AR070315A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Anticuerpos 1b20 antagonistas de pcsk9
MX336869B (es) 2008-11-03 2016-02-04 Alethia Biotherapeutics Inc Anticuerpos que bloquean espicificamente la actividad biologica de un antigeno de tumor.
WO2010068526A1 (fr) 2008-12-12 2010-06-17 Merck Sharp & Dohme Corp. Immunodosage de pcsk9
WO2011053783A2 (fr) 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Antagonistes et variants ax213 et ax132 pcsk9
AU2010313381A1 (en) 2009-10-30 2012-04-12 Merck Sharp & Dohme Corp. AX1 and AX189 PCSK9 antagonists and variants
HUE045943T2 (hu) 2011-03-31 2020-02-28 Adc Therapeutics Sa Veseasszociált antigén 1 és antigénkötõ fragmensei elleni antitestek
AU2013209234B2 (en) 2012-01-09 2017-11-09 Adc Therapeutics Sa Method for treating breast cancer
AR091462A1 (es) 2012-06-15 2015-02-04 Genentech Inc Anticuerpos anti-pcsk9, formulaciones, dosificacion y metodos de uso
WO2014170786A1 (fr) 2013-04-17 2014-10-23 Pfizer Inc. Dérivés de n-pipéridin-3-ylbenzamide dans le traitement des maladies cardiovasculaires
US8986691B1 (en) 2014-07-15 2015-03-24 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US9067998B1 (en) 2014-07-15 2015-06-30 Kymab Limited Targeting PD-1 variants for treatment of cancer
US9023359B1 (en) 2014-07-15 2015-05-05 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US9045548B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision Medicine by targeting rare human PCSK9 variants for cholesterol treatment
US8945560B1 (en) 2014-07-15 2015-02-03 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US8992927B1 (en) 2014-07-15 2015-03-31 Kymab Limited Targeting human NAV1.7 variants for treatment of pain
US9045545B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision medicine by targeting PD-L1 variants for treatment of cancer
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US8986694B1 (en) 2014-07-15 2015-03-24 Kymab Limited Targeting human nav1.7 variants for treatment of pain
US9034332B1 (en) 2014-07-15 2015-05-19 Kymab Limited Precision medicine by targeting rare human PCSK9 variants for cholesterol treatment
US8883157B1 (en) 2013-12-17 2014-11-11 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US8980273B1 (en) 2014-07-15 2015-03-17 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US9914769B2 (en) 2014-07-15 2018-03-13 Kymab Limited Precision medicine for cholesterol treatment
US9051378B1 (en) 2014-07-15 2015-06-09 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
US9150660B1 (en) 2014-07-15 2015-10-06 Kymab Limited Precision Medicine by targeting human NAV1.8 variants for treatment of pain
US9139648B1 (en) 2014-07-15 2015-09-22 Kymab Limited Precision medicine by targeting human NAV1.9 variants for treatment of pain
WO2018083248A1 (fr) 2016-11-03 2018-05-11 Kymab Limited Anticorps, combinaisons comprenant des anticorps, biomarqueurs, utilisations et procédés
GB2605925B (en) 2016-12-23 2023-02-22 Harvard College Gene editing of PCSK9

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932422A (en) * 1997-11-14 1999-08-03 Millennium Pharmaceuticals, Inc. Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase
WO2000057903A2 (fr) * 1999-03-26 2000-10-05 Human Genome Sciences, Inc. 48 proteines humaines secretees
JP2004501637A (ja) * 2000-06-26 2004-01-22 スージェン・インコーポレーテッド 新規プロテアーゼ

Also Published As

Publication number Publication date
CA2411971A1 (fr) 2001-12-27
WO2001098468A2 (fr) 2001-12-27
JP2004515217A (ja) 2004-05-27
EP1292684A2 (fr) 2003-03-19
WO2001098468A3 (fr) 2003-01-03

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