AU2001268173A1 - Microarrays for performing proteomic analyses - Google Patents
Microarrays for performing proteomic analysesInfo
- Publication number
- AU2001268173A1 AU2001268173A1 AU2001268173A AU6817301A AU2001268173A1 AU 2001268173 A1 AU2001268173 A1 AU 2001268173A1 AU 2001268173 A AU2001268173 A AU 2001268173A AU 6817301 A AU6817301 A AU 6817301A AU 2001268173 A1 AU2001268173 A1 AU 2001268173A1
- Authority
- AU
- Australia
- Prior art keywords
- array
- protein
- peptidomimetic
- binding
- microarrays
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004458 analytical method Methods 0.000 title abstract 2
- 238000002493 microarray Methods 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 239000000816 peptidomimetic Substances 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 2
- 238000003491 array Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
- 238000012916 structural analysis Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nanotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Provided are peptidomimetic protein-binding arrays, their manufacture, use, and application. The protein-binding array elements of the invention include a peptidomimetic segment linked to a solid support via a stable anchor. The invention contemplates peptidomimetic array element library synthesis, distribution, and spotting of array elements onto solid planar substrates, labeling of complex protein mixtures, and the analysis of differential protein binding to the array. The invention also enables the enrichment or purification, and subsequent sequencing or structural analysis of proteins that are identified as differential by the array screen. Kits including proteomic microarrays in accordance with the present invention are also provided.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20971100P | 2000-06-05 | 2000-06-05 | |
US60/209,711 | 2000-06-05 | ||
PCT/US2001/018066 WO2001094946A2 (en) | 2000-06-05 | 2001-06-04 | Microarrays for performing proteomic analyses |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001268173A1 true AU2001268173A1 (en) | 2001-12-17 |
Family
ID=22779937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001268173A Abandoned AU2001268173A1 (en) | 2000-06-05 | 2001-06-04 | Microarrays for performing proteomic analyses |
Country Status (10)
Country | Link |
---|---|
US (1) | US20020055125A1 (en) |
EP (1) | EP1297338B1 (en) |
JP (1) | JP2003536073A (en) |
AT (1) | ATE360207T1 (en) |
AU (1) | AU2001268173A1 (en) |
DE (1) | DE60127958D1 (en) |
DK (1) | DK1297338T3 (en) |
ES (1) | ES2281424T3 (en) |
PT (1) | PT1297338E (en) |
WO (1) | WO2001094946A2 (en) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7148058B2 (en) | 2000-06-05 | 2006-12-12 | Chiron Corporation | Protein microarrays on mirrored surfaces for performing proteomic analyses |
US7153682B2 (en) | 2000-06-05 | 2006-12-26 | Chiron Corporation | Microarrays on mirrored substrates for performing proteomic analyses |
US20020102617A1 (en) * | 2000-08-03 | 2002-08-01 | Macbeath Gavin | Protein microarrays |
WO2002012893A2 (en) * | 2000-08-03 | 2002-02-14 | Massachusetts Institute Of Technology | Microarrays of functional biomolecules, and uses therefor |
US7727713B2 (en) | 2001-06-20 | 2010-06-01 | Nuevolution A/S | Templated molecules and methods for using such molecules |
CA2477563A1 (en) * | 2001-12-21 | 2003-07-03 | Sense Proteomic Limited | Probe for mass spectrometry |
AU2002359130A1 (en) * | 2001-12-21 | 2003-07-15 | Biacore Ab | Immobilization of binding agents |
GB0205910D0 (en) * | 2002-03-13 | 2002-04-24 | Sense Proteomic Ltd | Arrays and methods |
GB2386372A (en) * | 2002-03-13 | 2003-09-17 | Amersham Biosciences Uk Ltd | The use of organic solvents in the preparation of arrays |
AU2003214031A1 (en) * | 2002-03-15 | 2003-09-29 | Nuevolution A/S | An improved method for synthesising templated molecules |
US6791690B2 (en) * | 2002-04-30 | 2004-09-14 | Agilent Technologies, Inc. | Reading dry chemical arrays |
AU2003245612A1 (en) * | 2002-07-11 | 2004-02-02 | The American National Red Cross | Method for identifying individual active entities from complex mixtures |
DE10233303A1 (en) * | 2002-07-22 | 2004-02-12 | Micronas Holding Gmbh | Sensor surface carrying immobilized probes, useful for detecting biomolecules, has regions that cause non-specific binding inactivated by immobilization of blocking agent |
AU2003247266A1 (en) * | 2002-08-01 | 2004-02-23 | Nuevolution A/S | Multi-step synthesis of templated molecules |
EP1545762A2 (en) * | 2002-09-27 | 2005-06-29 | Carlsberg A/S | Spatially encoded polymer matrix |
EP1406089A1 (en) * | 2002-10-02 | 2004-04-07 | Taiwan Unison Biotechnology Co. Ltd. | A method for selectively staining water soluble protein using reactive dye |
NZ538993A (en) | 2002-10-30 | 2008-04-30 | Nuevolution As | Method for the synthesis of a bifunctional complex |
ATE450609T1 (en) | 2002-12-19 | 2009-12-15 | Nuevolution As | SYNTHESIS METHOD GUIDED BY QUASI-RANDOM STRUCTURES AND FUNCTIONS |
US20070026397A1 (en) | 2003-02-21 | 2007-02-01 | Nuevolution A/S | Method for producing second-generation library |
WO2005003307A2 (en) * | 2003-06-17 | 2005-01-13 | The Regents Of The University Of California | Compositions and methods for analysis and manipulation of enzymes in biosynthetic proteomes |
ATE447626T1 (en) | 2003-09-18 | 2009-11-15 | Nuevolution As | METHOD FOR OBTAINING STRUCTURAL INFORMATION FROM ENCODED MOLECULES AND FOR SELECTING COMPOUNDS |
KR100518953B1 (en) * | 2003-09-19 | 2005-10-12 | 주식회사 제노포커스 | Method for Whole Surrounding Surface Display of Target Proteins Using Exosporium of Bacillus cereus Group |
WO2005033663A2 (en) * | 2003-09-30 | 2005-04-14 | Sequenom, Inc. | Methods of making substrates for mass spectrometry analysis and related devices |
WO2005040163A1 (en) | 2003-10-28 | 2005-05-06 | Dr. Reddy's Laboratories Ltd | Heterocyclic compounds that block the effects of advanced glycation end products (age) |
WO2005078122A2 (en) * | 2004-02-17 | 2005-08-25 | Nuevolution A/S | Method for enrichment involving elimination by mismatch hybridisation |
JP4736439B2 (en) * | 2005-01-25 | 2011-07-27 | 東レ株式会社 | Nucleic acid immobilization carrier |
WO2006124644A2 (en) * | 2005-05-12 | 2006-11-23 | Board Of Regents, The University Of Texas System | Protein and antibody profiling using small molecule microarrays |
WO2006138647A2 (en) * | 2005-06-16 | 2006-12-28 | Gtc Biotherapeutics, Inc. | Method of making recombinant human antibodies for use in biosensor technology |
EP1929010B1 (en) * | 2005-09-27 | 2013-12-18 | PolyBatics Limited | Uses of polymer particles |
DK3018206T3 (en) * | 2005-12-01 | 2021-11-15 | Nuevolution As | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES |
WO2008136058A1 (en) * | 2007-04-25 | 2008-11-13 | Shimadzu Corporation | Sample plate for laser desorption ionization and mass spectrometer utilizing the sample plate |
ES2742251T3 (en) | 2009-03-16 | 2020-02-13 | Pangu Biopharma Ltd | Compositions and methods comprising variants of histidyl tarn synthetase splicing that have non-canonical biological activities |
AU2010236913B2 (en) | 2009-03-31 | 2016-03-24 | Atyr Pharma, Inc. | Compositions and methods comprising aspartyl-tRNA synthetases having non-canonical biological activities |
RU2563822C2 (en) * | 2009-05-29 | 2015-09-20 | Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем | Peptoid ligands for autoimmune t-cell recovery and processing |
CA2764153C (en) * | 2009-06-02 | 2021-07-27 | The Board Of Regents Of The University Of Texas System | Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases |
TW201124726A (en) * | 2009-10-16 | 2011-07-16 | Univ Texas | Compositions and methods for producing coded peptoid libraries |
CA2797093C (en) | 2010-04-26 | 2019-10-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase |
US8961960B2 (en) | 2010-04-27 | 2015-02-24 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases |
US8993723B2 (en) | 2010-04-28 | 2015-03-31 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl-tRNA synthetases |
AU2011248490B2 (en) | 2010-04-29 | 2016-11-10 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases |
WO2011135459A2 (en) | 2010-04-29 | 2011-11-03 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy |
WO2011139907A2 (en) | 2010-04-29 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases |
EP2566495B1 (en) | 2010-05-03 | 2017-03-01 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases |
AU2011248355B2 (en) | 2010-05-03 | 2017-01-19 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Arginyl-tRNA synthetases |
WO2011140135A2 (en) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases |
EP2566499B1 (en) | 2010-05-04 | 2017-01-25 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex |
AU2011252990B2 (en) | 2010-05-14 | 2017-04-20 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases |
US9034598B2 (en) | 2010-05-17 | 2015-05-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases |
JP6046607B2 (en) | 2010-05-27 | 2016-12-21 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of glutaminyl tRNA synthetase |
CN103118694B (en) | 2010-06-01 | 2016-08-03 | Atyr医药公司 | The discovery for the treatment of, diagnosis and the antibody compositions relevant to the protein fragments of lysyl-tRNA synzyme |
CA2804416C (en) | 2010-07-12 | 2020-04-28 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases |
CA2808539C (en) | 2010-08-25 | 2021-05-25 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-trna synthetases |
EP2714927B1 (en) | 2011-06-01 | 2016-08-10 | Medical Prognosis Institute A/S | Methods and devices for prognosis of cancer relapse |
EP2814514B1 (en) | 2012-02-16 | 2017-09-13 | Atyr Pharma, Inc. | Histidyl-trna synthetases for treating autoimmune and inflammatory diseases |
CA2868928A1 (en) * | 2012-04-10 | 2013-10-17 | The Trustees Of Princeton University | Ultra-sensitive sensor |
MX367366B (en) | 2012-11-27 | 2019-08-16 | Univ Pontificia Catolica Chile | Compositions and methods for diagnosing thyroid tumors. |
CN105358979A (en) * | 2013-03-15 | 2016-02-24 | 普林斯顿大学理事会 | Analyte detection enhancement by targeted immobilization, surface amplification, and pixelated reading and analysis |
US10392667B2 (en) | 2013-06-07 | 2019-08-27 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy of fulvestrant in cancer patients |
US9897602B2 (en) | 2013-07-30 | 2018-02-20 | The Chinese University Of Hong Kong | Microarray substrate, microarray, microfluidic system and methods for preparing the same |
WO2015019861A1 (en) * | 2013-08-07 | 2015-02-12 | シチズンファインテックミヨタ株式会社 | Sample mounting plate |
NZ717526A (en) * | 2013-09-24 | 2020-03-27 | Entopsis Llc | Detectable arrays, systems for diagnosis, and methods of making and using the same |
EP3169815B1 (en) | 2014-07-15 | 2020-12-23 | Ontario Institute For Cancer Research | Methods and devices for predicting anthracycline treatment efficacy |
WO2017066454A2 (en) | 2015-10-14 | 2017-04-20 | X-Therma, Inc. | Compositions and methods for reducing ice crystal formation |
JP2020526774A (en) * | 2017-07-07 | 2020-08-31 | アヴィアーナ モレキュラー テクノロジーズ,エルエルシー | Bioactive coating for surface acoustic wave sensors |
CN112868086A (en) * | 2018-10-18 | 2021-05-28 | Dh科技发展私人贸易有限公司 | Method for functionalizing sampling elements for use with mass spectrometry systems |
WO2022120393A2 (en) * | 2020-12-02 | 2022-06-09 | Maxwell Biosciences, Inc. | Surface treatments utilizing immobilized antimicrobial peptide mimics |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3864085A (en) * | 1973-10-31 | 1975-02-04 | Princenton Biomedix Inc | Glutathione reagent and test method |
US5252743A (en) * | 1989-11-13 | 1993-10-12 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
US6075121A (en) * | 1990-05-15 | 2000-06-13 | Chiron Corporation | Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such |
IL98150A0 (en) * | 1990-05-17 | 1992-08-18 | Adeza Biomedical Corp | Highly reflective biogratings and method for theirhighly reflective biogratings and method production |
DE4039677A1 (en) * | 1990-12-12 | 1992-06-17 | Boehringer Mannheim Gmbh | UNIVERSAL BINDING FILM |
US5599695A (en) * | 1995-02-27 | 1997-02-04 | Affymetrix, Inc. | Printing molecular library arrays using deprotection agents solely in the vapor phase |
US6306584B1 (en) * | 1997-01-21 | 2001-10-23 | President And Fellows Of Harvard College | Electronic-property probing of biological molecules at surfaces |
NZ516848A (en) * | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
DE19741716A1 (en) * | 1997-09-22 | 1999-03-25 | Hoechst Ag | Recognition system |
US6087102A (en) * | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
IL138647A0 (en) * | 1998-03-23 | 2001-10-31 | Harvard College | Synthesis of compounds and libraries of compounds |
US6406921B1 (en) * | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
AU5879400A (en) * | 1999-06-29 | 2001-01-31 | Chiron Corporation | Arrays of biopolymeric agents and method for their production and use |
US7148058B2 (en) * | 2000-06-05 | 2006-12-12 | Chiron Corporation | Protein microarrays on mirrored surfaces for performing proteomic analyses |
US7153682B2 (en) * | 2000-06-05 | 2006-12-26 | Chiron Corporation | Microarrays on mirrored substrates for performing proteomic analyses |
-
2001
- 2001-06-04 EP EP01946078A patent/EP1297338B1/en not_active Expired - Lifetime
- 2001-06-04 WO PCT/US2001/018066 patent/WO2001094946A2/en active IP Right Grant
- 2001-06-04 JP JP2002502444A patent/JP2003536073A/en not_active Withdrawn
- 2001-06-04 AU AU2001268173A patent/AU2001268173A1/en not_active Abandoned
- 2001-06-04 DK DK01946078T patent/DK1297338T3/en active
- 2001-06-04 PT PT01946078T patent/PT1297338E/en unknown
- 2001-06-04 AT AT01946078T patent/ATE360207T1/en not_active IP Right Cessation
- 2001-06-04 US US09/874,091 patent/US20020055125A1/en not_active Abandoned
- 2001-06-04 ES ES01946078T patent/ES2281424T3/en not_active Expired - Lifetime
- 2001-06-04 DE DE60127958T patent/DE60127958D1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2281424T3 (en) | 2007-10-01 |
JP2003536073A (en) | 2003-12-02 |
WO2001094946A2 (en) | 2001-12-13 |
US20020055125A1 (en) | 2002-05-09 |
EP1297338A2 (en) | 2003-04-02 |
EP1297338B1 (en) | 2007-04-18 |
WO2001094946A9 (en) | 2002-04-11 |
DE60127958D1 (en) | 2007-05-31 |
WO2001094946A3 (en) | 2003-01-30 |
DK1297338T3 (en) | 2007-06-11 |
PT1297338E (en) | 2007-05-31 |
ATE360207T1 (en) | 2007-05-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001268173A1 (en) | Microarrays for performing proteomic analyses | |
WO2004005319A3 (en) | Microarrays on mirrored substrates for performing proteomic analyses | |
WO2004005477A3 (en) | Protein microarrays on mirrored surfaces for performing proteomic analyses | |
Righetti et al. | The ProteoMiner and the FortyNiners: searching for gold nuggets in the proteomic arena | |
PT1007654E (en) | PROTEIN EXPRESSION LIBRARY OR IN VITRO PEPTIDE | |
NZ501838A (en) | Retentate chromatography and protein chip arrays with applications in biology and medicine | |
HUP0200400A2 (en) | Protein isolation and analysis | |
NO963371L (en) | Hematopoietic protein as well as materials and methods for making it | |
US20160054331A1 (en) | Method for the detection and/or enrichment of analyte proteins and/or analyte peptides from a complex protein mixture | |
ATE495252T1 (en) | NOVEL PHAGE DISPLAY TECHNOLOGIES | |
JPH1025299A (en) | Aligned peptide, and detection of bound/interaction site in protein using the same | |
WO2007027906A3 (en) | Reagents for the detection of protein phosphorylation in leukemia signaling pathways | |
DE50213370D1 (en) | MICROFLUIDIC EXTRACTION PROCESS | |
Hata et al. | Two-dimensional HPLC on-line analysis of phosphopeptides using titania and monolithic columns | |
ATE311443T1 (en) | METHODS FOR SCREENING PROTEINS | |
WO2006086111A3 (en) | Reagents for the detection of protein phosphorylation in leukemia signaling pathways | |
WO2009003952A3 (en) | Column and method for preparing a biological sample for protein profiling | |
ATE322684T1 (en) | SRC SH3 BINDING PEPTIDES AND METHOD FOR ISOLATION AND USE THEREOF | |
DE602006011350D1 (en) | IN SITU PROTEIN MICROARRAY ASSEMBLY | |
NO20013563L (en) | Methods and assays for sequencing polypeptides | |
Harsha et al. | Proteomic strategies to characterize signaling pathways | |
WO2001069247A3 (en) | Methods of making and using microarrays of anti-ligands for the analysis of protein expression in cells | |
Zeng et al. | Improved CILAT reagents for quantitative proteomics | |
WO2001085912A3 (en) | Presenilin enhancers | |
AU2003256016A1 (en) | Differential labeling for quantitative analysis of complex protein mixtures by trifunctional synthetic peptide based reagents with iodoacetamido groups |