AU2001262027A1 - Use of substances that act as cascade inhibitors of the Raf/MEK/ERK signal cascade, for producing a medicament to treat DNA and RNA viruses - Google Patents
Use of substances that act as cascade inhibitors of the Raf/MEK/ERK signal cascade, for producing a medicament to treat DNA and RNA virusesInfo
- Publication number
- AU2001262027A1 AU2001262027A1 AU2001262027A AU2001262027A AU2001262027A1 AU 2001262027 A1 AU2001262027 A1 AU 2001262027A1 AU 2001262027 A AU2001262027 A AU 2001262027A AU 2001262027 A AU2001262027 A AU 2001262027A AU 2001262027 A1 AU2001262027 A1 AU 2001262027A1
- Authority
- AU
- Australia
- Prior art keywords
- cascade
- raf
- mek
- medicament
- substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-butanone Chemical group CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 title 1
- 241000450599 DNA viruses Species 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 241001493065 dsRNA viruses Species 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10017480.9 | 2000-04-07 | ||
DE10017480A DE10017480A1 (en) | 2000-04-07 | 2000-04-07 | Use of substances that act as MEK inhibitors for the manufacture of a medicament against DNA and RNA viruses |
PCT/DE2001/001292 WO2001076570A2 (en) | 2000-04-07 | 2001-04-05 | Use of substances that act as cascade inhibitors of the raf/mek/erk signal cascade, for producing a medicament to treat dna and rna viruses |
Publications (3)
Publication Number | Publication Date |
---|---|
AU2001262027A1 true AU2001262027A1 (en) | 2002-01-10 |
AU2001262027B2 AU2001262027B2 (en) | 2006-03-09 |
AU2001262027B8 AU2001262027B8 (en) | 2006-04-06 |
Family
ID=7638027
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU6202701A Pending AU6202701A (en) | 2000-04-07 | 2001-04-05 | Use of substances that act as cascade inhibitors of the raf/mek/erk signal cascade, for producing a medicament to treat dna and rna viruses |
AU2001262027A Expired AU2001262027B8 (en) | 2000-04-07 | 2001-04-05 | Use of substances that act as cascade inhibitors of the Raf/MEK/ERK signal cascade, for producing a medicament to treat DNA and RNA viruses |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU6202701A Pending AU6202701A (en) | 2000-04-07 | 2001-04-05 | Use of substances that act as cascade inhibitors of the raf/mek/erk signal cascade, for producing a medicament to treat dna and rna viruses |
Country Status (10)
Country | Link |
---|---|
US (3) | US20030060469A1 (en) |
EP (1) | EP1274421B1 (en) |
JP (1) | JP2004505891A (en) |
CN (1) | CN1268329C (en) |
AT (1) | ATE334670T1 (en) |
AU (2) | AU6202701A (en) |
CA (1) | CA2405307C (en) |
DE (2) | DE10017480A1 (en) |
ES (1) | ES2269404T3 (en) |
WO (1) | WO2001076570A2 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL149462A0 (en) * | 2001-05-09 | 2002-11-10 | Warner Lambert Co | Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor |
DE10138912A1 (en) * | 2001-08-08 | 2003-02-27 | Medinnova Ges Med Innovationen | Use of active substances for the prophylaxis and / or therapy of viral diseases as well as test system for finding such active substances |
US20040175384A1 (en) * | 2003-12-12 | 2004-09-09 | Mohapatra Shyam S. | Protein kinase C as a target for the treatment of respiratory syncytial virus |
CA2522333A1 (en) * | 2003-04-14 | 2004-10-21 | Novartis Ag | Methods for treating proliferative diseases and for monitoring the effectiveness of treatment of proliferative diseases |
WO2005007616A1 (en) * | 2003-07-23 | 2005-01-27 | Warner-Lambert Company Llc | Diphenylamino ketone derivatives as mek inhibitors |
RU2352558C2 (en) * | 2003-10-21 | 2009-04-20 | Уорнер-Ламберт Компани Ллс | Polymorphic form of n-[(r)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide |
US8592368B2 (en) * | 2003-12-19 | 2013-11-26 | University Of South Florida | JAK/STAT inhibitors and MAPK/ERK inhibitors for RSV infection |
CN103221043B (en) | 2010-08-05 | 2016-04-06 | 卡斯西部储备大学 | Be used for the treatment of neuron and connect stunted ERK inhibitor |
EP2714037B1 (en) | 2011-05-25 | 2016-07-13 | Université Paris Descartes | Erk inhibitors for use in treating spinal muscular atrophy |
AU2013328824B2 (en) | 2012-10-08 | 2018-04-05 | Atriva Therapeutics Gmbh | MEK inhibitors in the treatment of virus diseases |
PT3697405T (en) * | 2017-10-17 | 2021-08-27 | Atriva Therapeutics Gmbh | Novel mek-inhibitor for the treatment of viral and bacterial infections |
EP3708684B1 (en) | 2019-03-15 | 2022-03-02 | Primetals Technologies Austria GmbH | Method for direct reduction in a fluidised bed |
WO2020188015A1 (en) | 2019-03-21 | 2020-09-24 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
LU101183B1 (en) | 2019-04-16 | 2020-10-16 | Atriva Therapeutics Gmbh | Novel mek-inhibitor for the treatment of viral and bacterial infections |
AU2020338695A1 (en) | 2019-08-27 | 2022-03-24 | Atriva Therapeutics Gmbh | Combinations of mek inhibitors with cap-dependent endonuclease inhibitors |
AU2020362953A1 (en) | 2019-10-08 | 2022-04-14 | Atriva Therapeutics Gmbh | MEK inhibitors for the treatment of hantavirus infections |
WO2021089791A1 (en) | 2019-11-08 | 2021-05-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998037881A1 (en) * | 1997-02-28 | 1998-09-03 | Warner Lambert Company | Method of treating or preventing septic shock by administering a mek inhibitor |
BR9810385A (en) * | 1997-07-01 | 2000-09-05 | Warner Lambert Co | Derivatives of benzoic acid 2- (4-bromine or 4-iodine phenylamino) and their use as mek inhibitors |
AU757046B2 (en) * | 1997-07-01 | 2003-01-30 | Warner-Lambert Company | 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors |
CN101317589A (en) * | 1998-07-28 | 2008-12-10 | 艾科斯迈特技术公司 | Synergistic and residual pesticidal compositions containing plant essential oils. |
AU2203800A (en) * | 1999-01-07 | 2000-07-24 | Warner-Lambert Company | Antiviral method using mek inhibitors |
DE69928286T2 (en) * | 1999-01-13 | 2006-07-13 | Warner-Lambert Co. Llc | BENZENESULFONAMIDE DERIVATIVES AND THEIR USE AS MEK INHIBITORS |
JP2002534515A (en) * | 1999-01-13 | 2002-10-15 | ワーナー−ランバート・カンパニー | 1-heterocyclic-substituted diarylamines |
JP2001055376A (en) * | 1999-01-13 | 2001-02-27 | Warner Lambert Co | Diaryl amine |
US6316462B1 (en) * | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
-
2000
- 2000-04-07 DE DE10017480A patent/DE10017480A1/en not_active Withdrawn
-
2001
- 2001-04-05 DE DE50110618T patent/DE50110618D1/en not_active Expired - Lifetime
- 2001-04-05 WO PCT/DE2001/001292 patent/WO2001076570A2/en active IP Right Grant
- 2001-04-05 AU AU6202701A patent/AU6202701A/en active Pending
- 2001-04-05 AT AT01935945T patent/ATE334670T1/en active
- 2001-04-05 AU AU2001262027A patent/AU2001262027B8/en not_active Expired
- 2001-04-05 CN CNB01810827XA patent/CN1268329C/en not_active Expired - Lifetime
- 2001-04-05 CA CA2405307A patent/CA2405307C/en not_active Expired - Lifetime
- 2001-04-05 EP EP01935945A patent/EP1274421B1/en not_active Expired - Lifetime
- 2001-04-05 JP JP2001574088A patent/JP2004505891A/en active Pending
- 2001-04-05 US US10/240,904 patent/US20030060469A1/en not_active Abandoned
- 2001-04-05 ES ES01935945T patent/ES2269404T3/en not_active Expired - Lifetime
-
2004
- 2004-10-21 US US10/970,118 patent/US20050215627A1/en not_active Abandoned
-
2009
- 2009-05-21 US US12/470,441 patent/US20100137431A1/en not_active Abandoned
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