AU2001260979A1 - Inter-alpha-trypsin as a marker for sepsis - Google Patents

Inter-alpha-trypsin as a marker for sepsis

Info

Publication number
AU2001260979A1
AU2001260979A1 AU2001260979A AU2001260979A AU2001260979A1 AU 2001260979 A1 AU2001260979 A1 AU 2001260979A1 AU 2001260979 A AU2001260979 A AU 2001260979A AU 2001260979 A AU2001260979 A AU 2001260979A AU 2001260979 A1 AU2001260979 A1 AU 2001260979A1
Authority
AU
Australia
Prior art keywords
sepsis
trypsin
marker
alpha
inter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2001260979A
Other versions
AU2001260979B2 (en
Inventor
Douglas C Hixson
Yow-Pin Lim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhode Island Hospital
Original Assignee
Rhode Island Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/514,450 external-priority patent/US6660482B1/en
Application filed by Rhode Island Hospital filed Critical Rhode Island Hospital
Publication of AU2001260979A1 publication Critical patent/AU2001260979A1/en
Assigned to RHODE ISLAND HOSPITAL reassignment RHODE ISLAND HOSPITAL Request for Assignment Assignors: RHODE ISLAND HOSPITAL, A LIFESPAN PARTNER
Application granted granted Critical
Publication of AU2001260979B2 publication Critical patent/AU2001260979B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2001260979A 2000-02-28 2001-02-06 Inter-alpha-trypsin as a marker for sepsis Ceased AU2001260979B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/514,450 2000-02-28
US09/514,450 US6660482B1 (en) 2000-02-28 2000-02-28 Inter-alpha-trypsin inhibitor as a marker for sepsis
PCT/US2001/003827 WO2001063280A2 (en) 2000-02-28 2001-02-06 Inter-alpha-trypsin as a marker for sepsis

Publications (2)

Publication Number Publication Date
AU2001260979A1 true AU2001260979A1 (en) 2001-11-15
AU2001260979B2 AU2001260979B2 (en) 2006-09-28

Family

ID=24047191

Family Applications (2)

Application Number Title Priority Date Filing Date
AU6097901A Pending AU6097901A (en) 2000-02-28 2001-02-06 Inter-alpha-trypsin as a marker for sepsis
AU2001260979A Ceased AU2001260979B2 (en) 2000-02-28 2001-02-06 Inter-alpha-trypsin as a marker for sepsis

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU6097901A Pending AU6097901A (en) 2000-02-28 2001-02-06 Inter-alpha-trypsin as a marker for sepsis

Country Status (8)

Country Link
US (1) US6660482B1 (en)
EP (1) EP1295127B1 (en)
JP (1) JP4903965B2 (en)
AT (1) ATE309541T1 (en)
AU (2) AU6097901A (en)
CA (1) CA2401647A1 (en)
DE (1) DE60114823T2 (en)
WO (1) WO2001063280A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7015004B2 (en) * 2001-11-23 2006-03-21 Syn X Pharma, Inc. Inter-alpha trypsin inhibitor biopolymer marker indicative of insulin resistance
US6939716B2 (en) * 2001-09-19 2005-09-06 Washington University Method for detecting conditions indicative of sepsis
US7132244B2 (en) 2001-11-21 2006-11-07 Syn X Pharma, Inc. Betaine/GABA transport protein biopolymer marker indicative of insulin resistance
AU2003291483A1 (en) * 2002-11-12 2004-06-03 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
AU2003291482A1 (en) * 2002-11-12 2004-06-03 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
CN1829730A (en) 2002-11-12 2006-09-06 贝克顿迪金森公司 Diagnosis of sepsis or SIRS using biomarker profiles
JP5010920B2 (en) * 2003-11-08 2012-08-29 プロセラ・バイオロジクス Method for preparing human plasma-derived inter-alpha inhibitor protein for use in therapy and composition thereof
EP1869463A4 (en) 2005-04-15 2010-05-05 Becton Dickinson Co Diagnosis of sepsis
US8221995B2 (en) 2007-03-23 2012-07-17 Seok-Won Lee Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
WO2009123737A2 (en) 2008-04-03 2009-10-08 Becton, Dickinson And Company Advanced detection of sepsis
TR201808152T4 (en) 2008-05-28 2018-07-23 Prothera Biologics Inc Preparation of inter-alpha inhibitory proteins from blood and their composition.
AU2009325088B2 (en) * 2008-12-10 2014-06-19 Duke University Inhibition of inter-alpha trypsin inhibitor for the treatment of airway disease
WO2014039987A2 (en) * 2012-09-09 2014-03-13 Prothera Biologics, Inc. Treatment of disease using inter-alpha inhibitor proteins
KR102587810B1 (en) * 2017-04-25 2023-10-11 프로테라 바이오로직스, 인크. How to Quantify Inter-alpha Inhibitor Protein
US20230055086A1 (en) * 2021-08-19 2023-02-23 Prothera Biologics, Inc. Inter-alpha inhibitor proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0401508T3 (en) * 1989-05-13 1995-05-15 Bayer Ag Protease inhibitors, processes for their preparation, and drugs containing them
US5166133A (en) 1991-04-17 1992-11-24 Cetus Corporation Method for inhibing adhesion of white blood cells to endothelial cells
FR2711371B1 (en) 1993-10-18 1995-12-29 Aetsrn Process for the preparation of an inhibitory inter-alpha-trypsin concentrate for therapeutic use and concentrate obtained.
US5804370A (en) * 1994-06-08 1998-09-08 Critichem Medical Products Limited Early diagnosis of sepsis utilizing antigen-antibody interactions amplified by whole blood chemiluminescence
JP3327758B2 (en) * 1995-12-11 2002-09-24 株式会社いかがく Liver fibrosis screening method and diagnostic kit

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