AU2001260979A1 - Inter-alpha-trypsin as a marker for sepsis - Google Patents
Inter-alpha-trypsin as a marker for sepsisInfo
- Publication number
- AU2001260979A1 AU2001260979A1 AU2001260979A AU2001260979A AU2001260979A1 AU 2001260979 A1 AU2001260979 A1 AU 2001260979A1 AU 2001260979 A AU2001260979 A AU 2001260979A AU 2001260979 A AU2001260979 A AU 2001260979A AU 2001260979 A1 AU2001260979 A1 AU 2001260979A1
- Authority
- AU
- Australia
- Prior art keywords
- sepsis
- trypsin
- marker
- alpha
- inter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003550 marker Substances 0.000 title 1
- 239000012588 trypsin Substances 0.000 title 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/514,450 | 2000-02-28 | ||
US09/514,450 US6660482B1 (en) | 2000-02-28 | 2000-02-28 | Inter-alpha-trypsin inhibitor as a marker for sepsis |
PCT/US2001/003827 WO2001063280A2 (en) | 2000-02-28 | 2001-02-06 | Inter-alpha-trypsin as a marker for sepsis |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2001260979A1 true AU2001260979A1 (en) | 2001-11-15 |
AU2001260979B2 AU2001260979B2 (en) | 2006-09-28 |
Family
ID=24047191
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU6097901A Pending AU6097901A (en) | 2000-02-28 | 2001-02-06 | Inter-alpha-trypsin as a marker for sepsis |
AU2001260979A Ceased AU2001260979B2 (en) | 2000-02-28 | 2001-02-06 | Inter-alpha-trypsin as a marker for sepsis |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU6097901A Pending AU6097901A (en) | 2000-02-28 | 2001-02-06 | Inter-alpha-trypsin as a marker for sepsis |
Country Status (8)
Country | Link |
---|---|
US (1) | US6660482B1 (en) |
EP (1) | EP1295127B1 (en) |
JP (1) | JP4903965B2 (en) |
AT (1) | ATE309541T1 (en) |
AU (2) | AU6097901A (en) |
CA (1) | CA2401647A1 (en) |
DE (1) | DE60114823T2 (en) |
WO (1) | WO2001063280A2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7015004B2 (en) * | 2001-11-23 | 2006-03-21 | Syn X Pharma, Inc. | Inter-alpha trypsin inhibitor biopolymer marker indicative of insulin resistance |
US6939716B2 (en) * | 2001-09-19 | 2005-09-06 | Washington University | Method for detecting conditions indicative of sepsis |
US7132244B2 (en) | 2001-11-21 | 2006-11-07 | Syn X Pharma, Inc. | Betaine/GABA transport protein biopolymer marker indicative of insulin resistance |
AU2003291483A1 (en) * | 2002-11-12 | 2004-06-03 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
AU2003291482A1 (en) * | 2002-11-12 | 2004-06-03 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
CN1829730A (en) | 2002-11-12 | 2006-09-06 | 贝克顿迪金森公司 | Diagnosis of sepsis or SIRS using biomarker profiles |
JP5010920B2 (en) * | 2003-11-08 | 2012-08-29 | プロセラ・バイオロジクス | Method for preparing human plasma-derived inter-alpha inhibitor protein for use in therapy and composition thereof |
EP1869463A4 (en) | 2005-04-15 | 2010-05-05 | Becton Dickinson Co | Diagnosis of sepsis |
US8221995B2 (en) | 2007-03-23 | 2012-07-17 | Seok-Won Lee | Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes |
WO2009123737A2 (en) | 2008-04-03 | 2009-10-08 | Becton, Dickinson And Company | Advanced detection of sepsis |
TR201808152T4 (en) | 2008-05-28 | 2018-07-23 | Prothera Biologics Inc | Preparation of inter-alpha inhibitory proteins from blood and their composition. |
AU2009325088B2 (en) * | 2008-12-10 | 2014-06-19 | Duke University | Inhibition of inter-alpha trypsin inhibitor for the treatment of airway disease |
WO2014039987A2 (en) * | 2012-09-09 | 2014-03-13 | Prothera Biologics, Inc. | Treatment of disease using inter-alpha inhibitor proteins |
KR102587810B1 (en) * | 2017-04-25 | 2023-10-11 | 프로테라 바이오로직스, 인크. | How to Quantify Inter-alpha Inhibitor Protein |
US20230055086A1 (en) * | 2021-08-19 | 2023-02-23 | Prothera Biologics, Inc. | Inter-alpha inhibitor proteins |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0401508T3 (en) * | 1989-05-13 | 1995-05-15 | Bayer Ag | Protease inhibitors, processes for their preparation, and drugs containing them |
US5166133A (en) | 1991-04-17 | 1992-11-24 | Cetus Corporation | Method for inhibing adhesion of white blood cells to endothelial cells |
FR2711371B1 (en) | 1993-10-18 | 1995-12-29 | Aetsrn | Process for the preparation of an inhibitory inter-alpha-trypsin concentrate for therapeutic use and concentrate obtained. |
US5804370A (en) * | 1994-06-08 | 1998-09-08 | Critichem Medical Products Limited | Early diagnosis of sepsis utilizing antigen-antibody interactions amplified by whole blood chemiluminescence |
JP3327758B2 (en) * | 1995-12-11 | 2002-09-24 | 株式会社いかがく | Liver fibrosis screening method and diagnostic kit |
-
2000
- 2000-02-28 US US09/514,450 patent/US6660482B1/en not_active Expired - Lifetime
-
2001
- 2001-02-06 WO PCT/US2001/003827 patent/WO2001063280A2/en active IP Right Grant
- 2001-02-06 DE DE60114823T patent/DE60114823T2/en not_active Expired - Lifetime
- 2001-02-06 CA CA002401647A patent/CA2401647A1/en not_active Abandoned
- 2001-02-06 EP EP01934830A patent/EP1295127B1/en not_active Expired - Lifetime
- 2001-02-06 JP JP2001562194A patent/JP4903965B2/en not_active Expired - Lifetime
- 2001-02-06 AU AU6097901A patent/AU6097901A/en active Pending
- 2001-02-06 AT AT01934830T patent/ATE309541T1/en active
- 2001-02-06 AU AU2001260979A patent/AU2001260979B2/en not_active Ceased
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