AU2001237533A1 - Novel p-gp-inhibiting compounds - Google Patents

Novel p-gp-inhibiting compounds

Info

Publication number
AU2001237533A1
AU2001237533A1 AU2001237533A AU3753301A AU2001237533A1 AU 2001237533 A1 AU2001237533 A1 AU 2001237533A1 AU 2001237533 A AU2001237533 A AU 2001237533A AU 3753301 A AU3753301 A AU 3753301A AU 2001237533 A1 AU2001237533 A1 AU 2001237533A1
Authority
AU
Australia
Prior art keywords
novel
inhibiting compounds
inhibiting
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001237533A
Inventor
Abedel-Nasser Abulrob
Mark Gumbleton
Allan Denver Russell
Claire Simons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College Cardiff Consultants Ltd
Original Assignee
University College Cardiff Consultants Ltd
Cardiff University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University College Cardiff Consultants Ltd, Cardiff University filed Critical University College Cardiff Consultants Ltd
Publication of AU2001237533A1 publication Critical patent/AU2001237533A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
AU2001237533A 2000-02-17 2001-02-19 Novel p-gp-inhibiting compounds Abandoned AU2001237533A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0003685.5A GB0003685D0 (en) 2000-02-17 2000-02-17 Sensitisation of cellular material
GB0003685 2000-02-17
PCT/GB2001/000689 WO2001060827A1 (en) 2000-02-17 2001-02-19 Novel p-gp-inhibiting compounds

Publications (1)

Publication Number Publication Date
AU2001237533A1 true AU2001237533A1 (en) 2001-08-27

Family

ID=9885805

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001237533A Abandoned AU2001237533A1 (en) 2000-02-17 2001-02-19 Novel p-gp-inhibiting compounds

Country Status (3)

Country Link
AU (1) AU2001237533A1 (en)
GB (1) GB0003685D0 (en)
WO (1) WO2001060827A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4933730B2 (en) * 2001-05-04 2012-05-16 パラテック ファーマシューティカルズ インコーポレイテッド Transcription factor modulating compounds and methods of use thereof
US7148252B2 (en) * 2001-10-03 2006-12-12 Signal Pharmaceuticals, Llc Use of benzopyranones for treating or preventing a primary brain cancer or a brain metastasis
TW200403072A (en) * 2002-01-23 2004-03-01 Upjohn Co Combination therapy for the treatment of bacterial infections
FR2873585B1 (en) * 2004-07-27 2006-11-17 Aventis Pharma Sa NEW GALENIC FORMULATIONS OF ACTIVE PRINCIPLES

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0643693B1 (en) * 1992-02-06 1999-07-28 Merrell Pharmaceuticals Inc. Reversal of multi-drug resistance by triphenyl-piperidine derivatives
US5716982A (en) * 1995-06-07 1998-02-10 Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences Retinoids and methods of use of same
US5820915A (en) * 1996-06-27 1998-10-13 Bioavailability Systems, L.L.C. Method for the preparation of a first-pass effective citrus-derived substance and product thereof
WO1998017667A1 (en) * 1996-10-18 1998-04-30 Wayne State University 6',7'-dihydroxybergamottin, a cytochrome p450 ihnibitor in grapefruit juice

Also Published As

Publication number Publication date
GB0003685D0 (en) 2000-04-05
WO2001060827A1 (en) 2001-08-23

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