AU2001259935A1 - Novel of preparation hypericin bonded with poly-n-vinylamides - Google Patents

Novel of preparation hypericin bonded with poly-n-vinylamides

Info

Publication number
AU2001259935A1
AU2001259935A1 AU2001259935A AU5993501A AU2001259935A1 AU 2001259935 A1 AU2001259935 A1 AU 2001259935A1 AU 2001259935 A AU2001259935 A AU 2001259935A AU 5993501 A AU5993501 A AU 5993501A AU 2001259935 A1 AU2001259935 A1 AU 2001259935A1
Authority
AU
Australia
Prior art keywords
poly
hypericin
vinylamides
bonded
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001259935A
Inventor
Andreas Kubin
Hans Gunter Loew
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2001259935A1 publication Critical patent/AU2001259935A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

The invention relates to an active agent combination for diagnosing and treating tumours, comprising a water-soluble complex or a water-soluble compound of pure hypericin and a poly-N-vinylamide, especially PVP.
AU2001259935A 2000-05-23 2001-05-21 Novel of preparation hypericin bonded with poly-n-vinylamides Abandoned AU2001259935A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT8962000A AT408835B8 (en) 2000-05-23 2000-05-23 PREPARATION OF HYPERICIN TIED TO POLYVINYLPYRROLIDONE (PVP) DIFFERENT GRADES OF POLYMERIZATION AND CROSSLINKING
AT896/2000 2000-05-23
PCT/AT2001/000159 WO2001089576A2 (en) 2000-05-23 2001-05-21 Preparation hypericin bonded with poly-n-vinylamides

Publications (1)

Publication Number Publication Date
AU2001259935A1 true AU2001259935A1 (en) 2001-12-03

Family

ID=3682865

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001259935A Abandoned AU2001259935A1 (en) 2000-05-23 2001-05-21 Novel of preparation hypericin bonded with poly-n-vinylamides

Country Status (8)

Country Link
US (1) US7390510B2 (en)
EP (1) EP1289562B1 (en)
AT (2) AT408835B8 (en)
AU (1) AU2001259935A1 (en)
DE (1) DE50104978D1 (en)
ES (1) ES2236229T3 (en)
PT (1) PT1289562E (en)
WO (1) WO2001089576A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10261825A1 (en) * 2002-12-20 2004-07-01 Charité - Universitätsmedizin Berlin (Charité) Use of hypericin and / or its derivatives for tumor prevention
DE102004020619B4 (en) * 2004-04-27 2011-05-05 Schölly Fiberoptic GmbH auxiliary device
US20090117053A1 (en) * 2007-11-06 2009-05-07 Boston Scientific Scimed, Inc. Local delivery of 5-aminolevulinic-acid based compounds to tissues and organs for diagnostic and therapeutic purposes
US10143751B2 (en) 2015-09-28 2018-12-04 Sanochemia Pharmazeutika Ag Photodynamic therapy, formulation usable for this purpose, and method for the production and use thereof
US9629932B2 (en) * 2015-09-28 2017-04-25 Sanochemia Pharmazeutika Ag Photodynamic diagnosis, formulations usable as photosensitizers for this purpose, method for the production and use thereof
EP3593815A1 (en) * 2018-07-13 2020-01-15 Planta Naturstoffe Vertriebsges.m.b.h. Hypericin-pvp complex with high hypericin content

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08505054A (en) * 1992-12-23 1996-06-04 アイオア ステート ユニバーシティー リサーチ ファンデーション インコーポレーテッド Molecular flash
DE4434170C1 (en) * 1994-09-24 1996-03-28 Krewel Werke Gmbh St. John's wort extracts
JPH09262279A (en) * 1996-03-29 1997-10-07 Japan Atom Energy Res Inst Production of adhesive hydorgel
DE19756677A1 (en) * 1997-12-19 1999-06-24 Krewel Meuselbach Gmbh Per-oral dry plant extract
DE19814014A1 (en) * 1997-12-19 1999-09-30 Krewel Meuselbach Gmbh Medicinal plant dry extracts
US6063401A (en) * 1998-05-06 2000-05-16 M.E. Cody Products, Inc. Plantago major and hypericum perforatum compound for use in treating a tobacco or nicotine habit
IT1301678B1 (en) * 1998-06-10 2000-07-07 Indena Spa HYPERICUM PERFORATUM EXTRACTS AND FORMULATIONS CONTAINING THEM.
WO2000025824A2 (en) * 1998-11-04 2000-05-11 Dr. Willmar Schwabe Gmbh & Co. Stable preparations with hyperforin
EP1202706A1 (en) * 1999-07-22 2002-05-08 Pericor Science, Inc. Lysine oxidase linkage of agents to tissue
IL131508A (en) * 1999-08-19 2006-12-10 David Cohen Microencapsulated and controlled-release formulations of isoflavone from enriched fractions of soy and other plants
US7205008B2 (en) * 2000-03-15 2007-04-17 Proteotech, Inc. Methods of treating Alzheimer's disease and other amyloidoses using Hypericum perforatum and derivatives thereof
CA2408323C (en) * 2000-05-08 2012-06-12 The University Of British Columbia Drug delivery systems for photodynamic therapy
US7282215B2 (en) * 2000-05-08 2007-10-16 The University Of British Columbia Supports for photosensitizer formulations

Also Published As

Publication number Publication date
AT408835B (en) 2002-03-25
US7390510B2 (en) 2008-06-24
PT1289562E (en) 2005-05-31
WO2001089576A3 (en) 2002-06-06
DE50104978D1 (en) 2005-02-03
ATE285796T1 (en) 2005-01-15
AT408835B8 (en) 2002-07-25
ATA8962000A (en) 2001-08-15
EP1289562A2 (en) 2003-03-12
WO2001089576A2 (en) 2001-11-29
EP1289562B1 (en) 2004-12-29
ES2236229T3 (en) 2005-07-16
US20060127349A1 (en) 2006-06-15

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