AU2001256164A1 - Chroman derivatives as estrogenic compounds - Google Patents

Chroman derivatives as estrogenic compounds

Info

Publication number
AU2001256164A1
AU2001256164A1 AU2001256164A AU5616401A AU2001256164A1 AU 2001256164 A1 AU2001256164 A1 AU 2001256164A1 AU 2001256164 A AU2001256164 A AU 2001256164A AU 5616401 A AU5616401 A AU 5616401A AU 2001256164 A1 AU2001256164 A1 AU 2001256164A1
Authority
AU
Australia
Prior art keywords
estrogenic compounds
chroman derivatives
chroman
derivatives
estrogenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001256164A
Other languages
English (en)
Inventor
Neeltje Miranda Teerhuis
Gerrit Herman Veeneman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of AU2001256164A1 publication Critical patent/AU2001256164A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2001256164A 2000-03-01 2001-02-26 Chroman derivatives as estrogenic compounds Abandoned AU2001256164A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00200713 2000-03-01
EP00200713 2000-03-01
PCT/EP2001/002144 WO2001064665A1 (fr) 2000-03-01 2001-02-26 Derives de chromane en tant que composes oestrogeniques

Publications (1)

Publication Number Publication Date
AU2001256164A1 true AU2001256164A1 (en) 2001-09-12

Family

ID=8171123

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001256164A Abandoned AU2001256164A1 (en) 2000-03-01 2001-02-26 Chroman derivatives as estrogenic compounds

Country Status (9)

Country Link
US (3) US7214706B2 (fr)
EP (1) EP1282615B1 (fr)
JP (1) JP4896335B2 (fr)
AR (1) AR027571A1 (fr)
AT (1) ATE529419T1 (fr)
AU (1) AU2001256164A1 (fr)
CO (1) CO5261596A1 (fr)
PE (1) PE20011077A1 (fr)
WO (1) WO2001064665A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100950616B1 (ko) * 2001-11-19 2010-04-01 일라이 릴리 앤드 캄파니 선택적인 에스트로겐 수용체-베타 효능제로서의 치환된벤조피란
EP1790644A1 (fr) * 2001-11-19 2007-05-30 Eli Lilly And Company Benzopyranes substitués comme agonists du receptor beta-estrogen
US6630508B1 (en) 2002-02-11 2003-10-07 Eli Lilly And Company Substituted benzopyrans as selective estrogen receptor β agonists
AU2003212856A1 (en) * 2002-03-01 2003-09-16 Eli Lilly And Company Substituted benzopyrans as selective estrogen receptor-beta agonists
PT1626974E (pt) 2003-04-21 2008-11-14 Lilly Co Eli Benzopiranos substituídos como agonistas selectivos do receptor beta de estrogénio
EP1618102B1 (fr) 2003-04-21 2010-02-10 Eli Lilly And Company Benzopyranes substitues utiles en tant qu'agonistes selectifs du recepteur beta des oestrogenes
CA2578164A1 (fr) 2004-09-07 2006-03-16 Wyeth 6h-[1]benzopyrano[4,3-b]quinolines et leur utilisation comme agents oestrogenes
EP1805160B1 (fr) 2004-10-18 2011-04-06 Eli Lilly And Company Benzopyranes substitues utilises comme agonistes selectifs du recepteur d'oestrogenes beta
US9604931B2 (en) 2007-01-22 2017-03-28 Gtx, Inc. Nuclear receptor binding agents
EA201692214A1 (ru) 2007-01-22 2017-11-30 ДЖиТиЭкс, ИНК. Вещества, связывающие ядерные рецепторы
US9623021B2 (en) * 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
TW201043595A (en) * 2009-03-13 2010-12-16 Organon Nv Tetrahydronaphthalen-2-ol derivatives
US8063102B2 (en) 2009-03-13 2011-11-22 N.V. Organon Tetrahydronaphthalen-2-ol derivatives
US11511035B2 (en) 2016-07-28 2022-11-29 Cerebral Therapeutics, Inc. Implantable intraventricular sampling and infusion access device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340276A (en) 1964-04-01 1967-09-05 Ciba Geigy Corp 3, 4-diphenyl-chromans
DE1543749A1 (de) 1966-02-16 1969-12-11 Merck Ag E Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
US5407955A (en) 1994-02-18 1995-04-18 Eli Lilly And Company Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease
HUP9702244A3 (en) * 1995-01-13 1999-12-28 Novo Nordisk As Use of 3,4-diphenyl chromans for manufacture of a pharmaceutical composition for treatment or prophylaxis of gynaecological disorders
CA2200423C (fr) 1996-03-26 2006-12-19 Sietse Mosselman Nouveaux recepteurs d'oestrogene
DE69718500T2 (de) 1996-10-28 2003-11-27 Novo Nordisk As (-)-enantiomere von cis-3,4-chromanderivaten zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen
US6465445B1 (en) * 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors

Also Published As

Publication number Publication date
US20060160889A1 (en) 2006-07-20
JP4896335B2 (ja) 2012-03-14
PE20011077A1 (es) 2001-12-12
CO5261596A1 (es) 2003-03-31
US7214706B2 (en) 2007-05-08
US7846966B2 (en) 2010-12-07
EP1282615A1 (fr) 2003-02-12
EP1282615B1 (fr) 2011-10-19
AR027571A1 (es) 2003-04-02
US20030069303A1 (en) 2003-04-10
JP2003525285A (ja) 2003-08-26
US7531571B2 (en) 2009-05-12
ATE529419T1 (de) 2011-11-15
US20090221695A1 (en) 2009-09-03
WO2001064665A1 (fr) 2001-09-07

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