AU2001253208A1 - Solid phase synthesis of lxr ligands - Google Patents

Solid phase synthesis of lxr ligands

Info

Publication number
AU2001253208A1
AU2001253208A1 AU2001253208A AU5320801A AU2001253208A1 AU 2001253208 A1 AU2001253208 A1 AU 2001253208A1 AU 2001253208 A AU2001253208 A AU 2001253208A AU 5320801 A AU5320801 A AU 5320801A AU 2001253208 A1 AU2001253208 A1 AU 2001253208A1
Authority
AU
Australia
Prior art keywords
solid phase
phase synthesis
lxr ligands
lxr
ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001253208A
Inventor
Naonori Imazaki
Julio Medina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Tularik Inc
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd, Tularik Inc filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of AU2001253208A1 publication Critical patent/AU2001253208A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
AU2001253208A 2000-04-05 2001-04-05 Solid phase synthesis of lxr ligands Abandoned AU2001253208A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19491100P 2000-04-05 2000-04-05
US60/194,911 2000-04-05
US09/827,837 2001-04-04
US09/827,837 US6673543B2 (en) 2000-04-05 2001-04-04 Solid phase synthesis of LXR ligands
PCT/US2001/011242 WO2001077067A2 (en) 2000-04-05 2001-04-05 Solid phase synthesis of lxr ligands

Publications (1)

Publication Number Publication Date
AU2001253208A1 true AU2001253208A1 (en) 2001-10-23

Family

ID=26890519

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001253208A Abandoned AU2001253208A1 (en) 2000-04-05 2001-04-05 Solid phase synthesis of lxr ligands

Country Status (3)

Country Link
US (2) US6673543B2 (en)
AU (1) AU2001253208A1 (en)
WO (1) WO2001077067A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020188037A1 (en) * 1999-04-15 2002-12-12 Chudzik Stephen J. Method and system for providing bioactive agent release coating
US6924311B2 (en) * 2001-10-17 2005-08-02 X-Ceptor Therapeutics, Inc. Methods for affecting various diseases utilizing LXR compounds
GB2381866A (en) * 2001-11-12 2003-05-14 Karobio Ab Assays for liver X receptor (LXR) modulators
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
EP1572660B1 (en) 2002-12-20 2011-01-26 X-Ceptor Therapeutics, Inc. Isoquinolinone derivatives and their use as therapeutic agents

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4204002A (en) 1974-04-09 1980-05-20 Ciba-Geigy Corporation Methods of using N-(substituted)-N-alkoxy carbonyl anilino compounds
US4093738A (en) 1974-04-09 1978-06-06 Ciba-Geigy Corporation Microbicidally-active acylated anilino-carboxylic acid esters and their compositions
US4187232A (en) 1975-06-05 1980-02-05 Lilly Industries Limited Acylamino derivatives
GB1547564A (en) 1975-06-05 1979-06-20 Lilly Industries Ltd Acylated amino-heteroaryl compounds
DE2854600A1 (en) 1978-12-18 1980-06-26 Basf Ag SUBSTITUTED CYANAMID
US5449691A (en) * 1991-12-31 1995-09-12 Sterling Winthrop Inc. 3,4-disubstituted anilines-immunomodulating agents
GB9305672D0 (en) 1993-03-19 1993-05-05 Wyeth John & Brother Ltd Amide derivatives
IT1282705B1 (en) 1996-02-28 1998-03-31 Recordati Chem Pharm USE OF 5-HT | A SEROTONINERGIC RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE
US5861532A (en) * 1997-03-04 1999-01-19 Chiron Corporation Solid-phase synthesis of N-alkyl amides
JP2001512110A (en) 1997-08-01 2001-08-21 レコルダチ エッセ．ア．，ケミカル アンド ファーマシューティカル カンパニー 1,4-disubstituted piperazine
CA2322444A1 (en) 1998-03-05 1999-09-10 Agouron Pharmaceuticals, Inc. Non-peptide gnrh agents
US6316503B1 (en) 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
WO2001060818A1 (en) * 2000-02-14 2001-08-23 Tularik Inc. Lxr modulators

Also Published As

Publication number Publication date
US20020072073A1 (en) 2002-06-13
US20040152132A1 (en) 2004-08-05
WO2001077067A2 (en) 2001-10-18
US6673543B2 (en) 2004-01-06
WO2001077067A3 (en) 2003-08-14

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