AU2001248505A1 - Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases - Google Patents

Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases

Info

Publication number
AU2001248505A1
AU2001248505A1 AU2001248505A AU4850501A AU2001248505A1 AU 2001248505 A1 AU2001248505 A1 AU 2001248505A1 AU 2001248505 A AU2001248505 A AU 2001248505A AU 4850501 A AU4850501 A AU 4850501A AU 2001248505 A1 AU2001248505 A1 AU 2001248505A1
Authority
AU
Australia
Prior art keywords
inhibitors
class
receptor tyrosine
tyrosine kinases
amine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001248505A
Inventor
Peter David Davis
David Festus Charles Moffat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Celltech Ltd
Original Assignee
Celltech Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech Chiroscience Ltd filed Critical Celltech Chiroscience Ltd
Publication of AU2001248505A1 publication Critical patent/AU2001248505A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001248505A 2000-03-29 2001-03-29 Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases Abandoned AU2001248505A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0007657 2000-03-29
GBGB0007657.0A GB0007657D0 (en) 2000-03-29 2000-03-29 Chemical compounds
PCT/GB2001/001438 WO2001072720A1 (en) 2000-03-29 2001-03-29 Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases

Publications (1)

Publication Number Publication Date
AU2001248505A1 true AU2001248505A1 (en) 2001-10-08

Family

ID=9888698

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001248505A Abandoned AU2001248505A1 (en) 2000-03-29 2001-03-29 Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases

Country Status (6)

Country Link
US (1) US7012076B2 (en)
EP (1) EP1268448A1 (en)
JP (1) JP2003528863A (en)
AU (1) AU2001248505A1 (en)
GB (1) GB0007657D0 (en)
WO (1) WO2001072720A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100379734C (en) 1999-12-24 2008-04-09 阿文蒂斯药物有限公司 Azaindoles
GB0110797D0 (en) * 2001-05-02 2001-06-27 Celltech R&D Ltd Chemical compounds
GB0115109D0 (en) 2001-06-21 2001-08-15 Aventis Pharma Ltd Chemical compounds
CA2494061C (en) * 2002-07-31 2011-06-14 Wayne R. Danter Protein tyrosine kinase inhibitors
US7629347B2 (en) * 2002-10-09 2009-12-08 Critical Outcome Technologies, Inc. Protein tyrosine kinase inhibitors
WO2008083491A1 (en) 2007-01-11 2008-07-17 Critical Outcome Technologies Inc. Compounds and method for treatment of cancer
EP2225226B1 (en) * 2007-12-26 2016-08-17 Critical Outcome Technologies, Inc. Compounds and their use in a method for treatment of cancer
EP2500340A1 (en) * 2008-01-25 2012-09-19 Syngenta Participations AG. 2-Cyanophenyl Sulfonamide Derivatives Useful as Pesticides
EP2279174A2 (en) * 2008-05-21 2011-02-02 Genentech, Inc. Arylsulfonamide compounds, compositions and methods of use
WO2010006438A1 (en) 2008-07-17 2010-01-21 Critical Outcome Technologies Inc. Thiosemicarbazone inhibitor compounds and cancer treatment methods
WO2011120153A1 (en) 2010-04-01 2011-10-06 Critical Outcome Technologies Inc. Compounds and method for treatment of hiv
CN103193691B (en) * 2012-01-06 2017-08-25 中国科学院上海药物研究所 Sulfonamides compound, pharmaceutical composition and its preparation method and application

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2473931A (en) * 1945-11-09 1949-06-21 Merck & Co Inc 2-and 4-sulfanilamido quinazoline
GB920019A (en) 1960-05-12 1963-03-06 Mead Johnson & Co 2-substituted sulphanilamidoquinazolines and process
AT252922B (en) 1965-03-11 1967-03-10 Biochemie Gmbh Process for the preparation of 2-alkoxy-substituted 4-sulfanilamido-quinazolines
GB1092737A (en) * 1965-06-02 1967-11-29 Mead Johnson & Co 2-methoxy-4-[n-glutarylsulfanilamido]quinazoline and process for preparing the same
GB9510757D0 (en) 1994-09-19 1995-07-19 Wellcome Found Therapeuticaly active compounds

Also Published As

Publication number Publication date
US20030153755A1 (en) 2003-08-14
EP1268448A1 (en) 2003-01-02
GB0007657D0 (en) 2000-05-17
US7012076B2 (en) 2006-03-14
JP2003528863A (en) 2003-09-30
WO2001072720A1 (en) 2001-10-04

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