AU2001248504A1 - Immunosuppressant n-acyles homoserine lactones - Google Patents
Immunosuppressant n-acyles homoserine lactonesInfo
- Publication number
- AU2001248504A1 AU2001248504A1 AU2001248504A AU4850401A AU2001248504A1 AU 2001248504 A1 AU2001248504 A1 AU 2001248504A1 AU 2001248504 A AU2001248504 A AU 2001248504A AU 4850401 A AU4850401 A AU 4850401A AU 2001248504 A1 AU2001248504 A1 AU 2001248504A1
- Authority
- AU
- Australia
- Prior art keywords
- acyles
- immunosuppressant
- homoserine lactones
- homoserine
- lactones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- UKAUYVFTDYCKQA-UHFFFAOYSA-N -2-Amino-4-hydroxybutanoic acid Natural products OC(=O)C(N)CCO UKAUYVFTDYCKQA-UHFFFAOYSA-N 0.000 title 1
- 229960003444 immunosuppressant agent Drugs 0.000 title 1
- 230000001861 immunosuppressant effect Effects 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0007588.7A GB0007588D0 (en) | 2000-03-30 | 2000-03-30 | N-Acyl homoserine lactones |
GB0007588 | 2000-03-30 | ||
PCT/GB2001/001435 WO2001074801A1 (fr) | 2000-03-30 | 2001-03-29 | N-acyl homoserine lactones a activite immunosuppressive |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001248504A1 true AU2001248504A1 (en) | 2001-10-15 |
Family
ID=9888642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001248504A Abandoned AU2001248504A1 (en) | 2000-03-30 | 2001-03-29 | Immunosuppressant n-acyles homoserine lactones |
Country Status (5)
Country | Link |
---|---|
US (1) | US20030171371A1 (fr) |
EP (1) | EP1268459A1 (fr) |
AU (1) | AU2001248504A1 (fr) |
GB (1) | GB0007588D0 (fr) |
WO (1) | WO2001074801A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6703513B1 (en) * | 2000-06-02 | 2004-03-09 | K-Quay Enterprises Llc | Production and use of derivatized homoserine lactones |
ATE363839T1 (de) * | 2001-01-08 | 2007-06-15 | Pathway Intermediates Ltd | Autoinducer-verbindungen und ihre verwendung |
GB0116312D0 (en) * | 2001-07-04 | 2001-08-29 | Univ Nottingham | "Compositions containing N-acyl homoserine lactones" |
GB0122026D0 (en) * | 2001-09-12 | 2001-10-31 | Univ Nottingham | Insulitis |
ES2382075T3 (es) | 2002-08-13 | 2012-06-05 | Haptogen Ltd | Procedimientos para el tratamiento de una enfermedad bacteriana infecciosa con un anticuerpo contra las moléculas señal derivadas de una antilactona o una lactona |
US7537906B2 (en) | 2003-01-29 | 2009-05-26 | Nobuhiko Nomura | Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone |
GB0407008D0 (en) | 2004-03-27 | 2004-04-28 | Haptogen Ltd | Methods for inducing rapid cell death (autolysis) in infectious bacteria |
GB0410958D0 (en) | 2004-05-15 | 2004-06-16 | Haptogen Ltd | Methods for reducing biofilm formation in infectious bacteria |
GB0610042D0 (en) * | 2006-05-22 | 2006-06-28 | Univ Nottingham | Substituted n-acyl homoserine lactones |
KR100841294B1 (ko) | 2006-12-04 | 2008-06-25 | 재단법인서울대학교산학협력재단 | 호모세린 락톤계 정족수 인식 길항제 및 이를 이용한생물막의 형성 방지 방법 |
US8501969B2 (en) | 2009-07-03 | 2013-08-06 | The National Institute for Biotechnology in the Negev Ltd. | Covalent inhibition of bacterial quorum sensing |
WO2014201507A1 (fr) * | 2013-06-21 | 2014-12-24 | Technological Resources Pty. Limited | Dérivés de lactone homosérine pour améliorer l'extraction des éléments minéraux pendant l'extraction biologique de minerais |
TWI594991B (zh) * | 2015-06-30 | 2017-08-11 | 中央研究院 | 第一型類升糖素肽調節子及其用途 |
WO2017058757A1 (fr) * | 2015-10-01 | 2017-04-06 | The University Of Toledo | Utilisation de dérivés d'acyl-homosérine lactone en tant qu'agents anti-thrombotiques |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4415493A (en) * | 1982-05-11 | 1983-11-15 | Scripps Clinic And Research Foundation | Immune modulator peptides |
GB9108307D0 (en) * | 1991-04-18 | 1991-06-05 | Univ Nottingham | Autoinducer |
EP0706393B1 (fr) * | 1993-07-02 | 1999-09-08 | The University Of Nottingham | Composes immunosuppresseurs et antiallergiques, tels que la lactone d'homoserine n-(3-oxohexanoyle) |
US5591872A (en) * | 1993-08-09 | 1997-01-07 | The University Of Iowa Research Foundation | Autoinducer molecule |
ATE342661T1 (de) * | 1997-06-18 | 2006-11-15 | Univ Montana State | Homoserinlactone zum regulieren von biofilmen und methoden zur anwendung |
GB9725599D0 (en) * | 1997-12-04 | 1998-02-04 | Univ Nottingham | Control of biofilm formation |
US6395282B1 (en) * | 1998-04-16 | 2002-05-28 | University Of Rochester | Immunogenic conjugates of Gram-negative bacterial autoinducer molecules |
US6337347B1 (en) * | 1998-06-18 | 2002-01-08 | The Research & Development Institute, Inc. | Autoinducer compounds |
-
2000
- 2000-03-30 GB GBGB0007588.7A patent/GB0007588D0/en not_active Ceased
-
2001
- 2001-03-29 WO PCT/GB2001/001435 patent/WO2001074801A1/fr not_active Application Discontinuation
- 2001-03-29 US US10/240,237 patent/US20030171371A1/en not_active Abandoned
- 2001-03-29 EP EP01921527A patent/EP1268459A1/fr not_active Withdrawn
- 2001-03-29 AU AU2001248504A patent/AU2001248504A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1268459A1 (fr) | 2003-01-02 |
GB0007588D0 (en) | 2000-05-17 |
US20030171371A1 (en) | 2003-09-11 |
WO2001074801A1 (fr) | 2001-10-11 |
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