AU2001240025A1 - Cell cycle proteins associated with rad9, compositions and methods of use - Google Patents

Cell cycle proteins associated with rad9, compositions and methods of use

Info

Publication number
AU2001240025A1
AU2001240025A1 AU2001240025A AU4002501A AU2001240025A1 AU 2001240025 A1 AU2001240025 A1 AU 2001240025A1 AU 2001240025 A AU2001240025 A AU 2001240025A AU 4002501 A AU4002501 A AU 4002501A AU 2001240025 A1 AU2001240025 A1 AU 2001240025A1
Authority
AU
Australia
Prior art keywords
rad9
compositions
methods
cell cycle
proteins associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001240025A
Inventor
Ying Luo
Xiang Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rigel Pharmaceuticals Inc
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of AU2001240025A1 publication Critical patent/AU2001240025A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03016—Phosphoprotein phosphatase (3.1.3.16), i.e. calcineurin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4739—Cyclin; Prad 1
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8114—Kunitz type inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001240025A 2000-03-02 2001-03-02 Cell cycle proteins associated with rad9, compositions and methods of use Abandoned AU2001240025A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/517,779 2000-03-02
US09/517,779 US6660511B1 (en) 2000-03-03 2000-03-03 Methods of screening for modulation of cell cycle
PCT/US2001/006849 WO2001064913A2 (en) 2000-03-02 2001-03-02 Cell cycle proteins associated with rad9, compositions and methods of use

Publications (1)

Publication Number Publication Date
AU2001240025A1 true AU2001240025A1 (en) 2001-09-12

Family

ID=24061194

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001240025A Abandoned AU2001240025A1 (en) 2000-03-02 2001-03-02 Cell cycle proteins associated with rad9, compositions and methods of use

Country Status (4)

Country Link
US (2) US6660511B1 (en)
EP (1) EP1261720A2 (en)
AU (1) AU2001240025A1 (en)
WO (1) WO2001064913A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1207394B1 (en) * 2000-11-14 2009-12-30 Roche Diagnostics GmbH Immunoassay for HIV protease inhibitors
ES2315365T3 (en) 2001-06-13 2009-04-01 Magnachem International Laboratories, Inc. FORMULATIONS OF LACTONE AND METHOD OF USE.
US7402392B2 (en) * 2001-10-03 2008-07-22 Vanderbilt University In vivo panning for ligands to radiation-induced molecules
EP1562930A4 (en) 2002-11-05 2008-12-10 Magnachem Int Lab Inc Synthetic lactone formulations and method of use
KR100698954B1 (en) * 2004-02-27 2007-03-26 제노마인(주) Use of novel phytochrome-interacting protein
WO2005102315A1 (en) 2004-04-23 2005-11-03 Magnachem International Laboratories, Inc. Synthetic lactone formulations for pain control
US20100322916A1 (en) * 2008-01-30 2010-12-23 Mccullough Amanda K Dna repair polypeptides and methods of delivery and use
WO2010011994A2 (en) * 2008-07-25 2010-01-28 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Polypeptides and uses thereof
JP2012507010A (en) 2008-10-24 2012-03-22 マグナケム インターナショナル ラボラトリーズ， インコーポレイテッド Method for screening compounds that selectively interact with RAD9

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998014606A1 (en) 1996-10-04 1998-04-09 South Alabama Medical Science Foundation Method for diminishing myocardial infarction using protein phosphatase inhibitors
CA2309888A1 (en) 1997-11-20 1999-06-03 South Alabama Medical Science Foundation Decreasing cell proliferation by decreasing levels of pp5
GB9727277D0 (en) * 1997-12-23 1998-02-25 Medical Res Council Assay
GB2348701B (en) 1999-03-19 2001-06-20 Kudos Pharm Ltd Assays,methods and means

Also Published As

Publication number Publication date
WO2001064913A2 (en) 2001-09-07
US20030211546A1 (en) 2003-11-13
WO2001064913A9 (en) 2003-01-16
EP1261720A2 (en) 2002-12-04
US20070238134A9 (en) 2007-10-11
WO2001064913A3 (en) 2002-04-18
US7384761B2 (en) 2008-06-10
US6660511B1 (en) 2003-12-09

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