AU2001239287A1 - Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material - Google Patents

Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material

Info

Publication number
AU2001239287A1
AU2001239287A1 AU2001239287A AU3928701A AU2001239287A1 AU 2001239287 A1 AU2001239287 A1 AU 2001239287A1 AU 2001239287 A AU2001239287 A AU 2001239287A AU 3928701 A AU3928701 A AU 3928701A AU 2001239287 A1 AU2001239287 A1 AU 2001239287A1
Authority
AU
Australia
Prior art keywords
bone tissue
vitro production
transplant material
cartilage
dimensional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001239287A
Inventor
Ursula Anderer
Karl-Gerd Fritsch
Olivera Josimovic-Alasevic
Jeanette Libera
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Co Don AG
Original Assignee
Co Don AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Co Don AG filed Critical Co Don AG
Publication of AU2001239287A1 publication Critical patent/AU2001239287A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655Chondrocytes; Cartilage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
AU2001239287A 2000-03-13 2001-03-09 Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material Abandoned AU2001239287A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10013223 2000-03-13
DE10013223A DE10013223C2 (en) 2000-03-13 2000-03-13 Process for the in vitro production of three-dimensional, vital cartilage or bone tissue and its use as a transplant material
PCT/EP2001/002698 WO2001068811A2 (en) 2000-03-13 2001-03-09 Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material

Publications (1)

Publication Number Publication Date
AU2001239287A1 true AU2001239287A1 (en) 2001-09-24

Family

ID=7635247

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001239287A Abandoned AU2001239287A1 (en) 2000-03-13 2001-03-09 Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material

Country Status (9)

Country Link
US (1) US7887843B2 (en)
EP (1) EP1265986B1 (en)
AU (1) AU2001239287A1 (en)
CA (1) CA2403120A1 (en)
CY (1) CY1117464T1 (en)
DE (1) DE10013223C2 (en)
DK (1) DK1265986T3 (en)
ES (1) ES2566053T3 (en)
WO (1) WO2001068811A2 (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10222896A1 (en) * 2002-05-23 2003-12-11 Biotissue Technologies Ag Process for the production of a three-dimensional and flat tissue graft
US7622562B2 (en) 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
DE10253066A1 (en) * 2002-11-07 2004-05-27 Co.Don Aktiengesellschaft Tissue substitute, useful for repairing lesions, e.g. in cardiac muscle, also for production of e.g. cytokines, comprises preformed three-dimensional tissue grown from suspension culture
AU2004246749A1 (en) * 2003-06-12 2004-12-23 Interface Biotech A/S A method for cell implantation
US7744869B2 (en) * 2003-08-20 2010-06-29 Ebi, Llc Methods of treatment using electromagnetic field stimulated mesenchymal stem cells
ES2403357T3 (en) 2003-12-11 2013-05-17 Isto Technologies Inc. Particle Cartilage System
US8148150B2 (en) * 2003-12-12 2012-04-03 Co.Don Ag Method for the production of intervertebral disk cell transplants and their use as transplantation material
US8241905B2 (en) * 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
JP4044579B2 (en) * 2005-08-02 2008-02-06 株式会社Pgリサーチ Artificial cartilage tissue
EP1916964A4 (en) 2005-08-26 2015-11-04 Zimmer Inc Implants and methods for repair, replacement and treatment of joint disease
EP1764117A1 (en) 2005-09-20 2007-03-21 Zimmer GmbH Implant for the repair of a cartilage defect and method for manufacturing the implant
US20070093905A1 (en) * 2005-10-21 2007-04-26 O'neil Michael J Degenerative disc regeneration techniques
US20080166329A1 (en) * 2005-10-24 2008-07-10 Hsing-Wen Sung Medical device and methods for living cell injection
WO2007087402A2 (en) 2006-01-24 2007-08-02 Brown University Cell aggregation and encapsulation device and method
KR20080091832A (en) * 2006-01-30 2008-10-14 유니버시티 오브 버지니아 페이턴트 파운데이션 Methods of preparing and characterizing mesenchymal stem cell aggregates and uses thereof
AU2007320031B2 (en) * 2006-10-06 2013-05-02 University Of Virginia Patent Foundation Methods and compositions useful for diabetic wound healing
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US20090012629A1 (en) 2007-04-12 2009-01-08 Isto Technologies, Inc. Compositions and methods for tissue repair
WO2010008905A2 (en) 2008-06-24 2010-01-21 The Curators Of The University Of Missouri Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same
WO2010005917A2 (en) * 2008-07-06 2010-01-14 The Curators Of The University Of Missouri Osteochondral implants, arthroplasty methods, devices, and systems
US20100098739A1 (en) * 2008-10-20 2010-04-22 University Of Virginia Patent Foundation Compositions and methods for modular soft tissue repair
TW201022435A (en) * 2008-12-02 2010-06-16 Univ Nat Taiwan Method for transferring a cell onto a carrier and the applications thereof
US8501476B2 (en) * 2009-10-07 2013-08-06 Brown University Assays and methods for fusing cell aggregates to form proto-tissues
CN102869391A (en) 2010-02-02 2013-01-09 密苏里大学管理者 Engineered biological nerve graft fabrication and application thereof
CA2812766C (en) 2010-10-21 2021-06-29 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
WO2013016547A2 (en) 2011-07-26 2013-01-31 The Curators Of The University Of Missouri Engineered comestible meat
US9468680B2 (en) 2011-09-22 2016-10-18 Brown University Differential effects of drugs on transport in a multi-layer 3D spheroid model
US9243278B2 (en) 2011-09-22 2016-01-26 Brown University Mechanotransduction by the synergistic action of heterotypic cell interactions
US9499779B2 (en) 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
EP2677027A1 (en) 2012-06-21 2013-12-25 Hochschule Lausitz Method for producing functional fusion tissue from human chondrocytes
US9332779B2 (en) 2014-02-05 2016-05-10 Modern Meadow, Inc. Dried food products formed from cultured muscle cells
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US10072241B2 (en) 2013-03-13 2018-09-11 Innovative Surface Technologies, Inc. Conical devices for three-dimensional aggregate(s) of eukaryotic cells
US9442105B2 (en) 2013-03-15 2016-09-13 Organovo, Inc. Engineered liver tissues, arrays thereof, and methods of making the same
KR20160036619A (en) 2013-07-31 2016-04-04 오가노보, 인크. Automated devices, systems, and methods for the fabrication of tissue
WO2015038988A1 (en) 2013-09-13 2015-03-19 Modern Meadow, Inc. Edible and animal-product-free microcarriers for engineered meat
CA3177480A1 (en) 2014-04-04 2015-10-08 Organovo, Inc. Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model
US9481868B2 (en) 2014-10-06 2016-11-01 Organovo, Inc. Engineered renal tissues, arrays thereof, and methods of making the same
WO2016073782A1 (en) 2014-11-05 2016-05-12 Organovo, Inc. Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same
DE102014222898A1 (en) * 2014-11-10 2016-05-12 Universität Konstanz Preparation and isolation of a native human dermal extracellular matrix
US11913166B2 (en) 2015-09-21 2024-02-27 Modern Meadow, Inc. Fiber reinforced tissue composites
KR101733137B1 (en) * 2015-12-30 2017-05-08 (주)엑셀세라퓨틱스 Method of production for 3D cartilage organoid block
US11542374B2 (en) 2016-02-15 2023-01-03 Modern Meadow, Inc. Composite biofabricated material
KR20190077407A (en) 2016-11-10 2019-07-03 오가노보, 인크. Bio-printed hair follicles and uses thereof
AU2018278185A1 (en) * 2017-05-30 2020-01-16 Katholieke Universiteit Leuven Engineering functional bone organs
EP3417888A1 (en) 2017-06-25 2018-12-26 co.don AG Method for producing transplantable cartilage tissue
AU2018253595A1 (en) 2017-11-13 2019-05-30 Modern Meadow, Inc. Biofabricated leather articles having zonal properties
RU2691916C1 (en) * 2018-05-03 2019-06-18 Федеральное государственное бюджетное учреждение "Новосибирский научно-исследовательский институт травматологии и ортопедии им. Я.Л. Цивьяна" Министерства здравоохранения Российской Федерации (ФГБУ "ННИИТО им. Я.Л. Цивьяна" Минздрава России) Method of surgical treatment of deforming osteoarthrosis of knee joint
MX2021008462A (en) 2019-01-17 2021-08-19 Modern Meadow Inc Layered collagen materials and methods of making the same.
EP3744831A1 (en) 2019-05-31 2020-12-02 co.don AG Method for cultivation of cartilage and spheroids thereof
CN111019888A (en) * 2020-01-10 2020-04-17 中怡(深圳)医疗科技集团有限公司 Sturgeon source-based primary chondrocyte extraction method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723331A (en) * 1994-05-05 1998-03-03 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
US5655546A (en) * 1995-06-07 1997-08-12 Halpern; Alan A. Method for cartilage repair
DE19540487A1 (en) * 1995-10-20 1997-04-24 Olaf Schultz Cell interaction system for induction of artificial 3-dimensional tissue
US6152964A (en) * 1996-03-01 2000-11-28 Isotis B.V. Method for in vitro production of bone
US6811776B2 (en) * 2000-12-27 2004-11-02 The Regents Of The University Of Michigan Process for ex vivo formation of mammalian bone and uses thereof

Also Published As

Publication number Publication date
EP1265986A2 (en) 2002-12-18
ES2566053T3 (en) 2016-04-08
DE10013223A1 (en) 2001-10-11
WO2001068811A3 (en) 2001-12-27
DE10013223C2 (en) 2002-07-18
CA2403120A1 (en) 2002-09-13
WO2001068811A2 (en) 2001-09-20
US20030153078A1 (en) 2003-08-14
EP1265986B1 (en) 2016-02-24
CY1117464T1 (en) 2017-04-26
US7887843B2 (en) 2011-02-15
DK1265986T3 (en) 2016-04-04

Similar Documents

Publication Publication Date Title
AU2001239287A1 (en) Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material
AU2002361860A1 (en) Calcium phosphate bone replacement materials and methods of use thereof
AU2001255767A1 (en) Methods and reagents for tissue engineering of cartilage in vitro
AU2002340807A1 (en) Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering
EP1534191A4 (en) Composition for the carrying and delivery of bone growth inducing material and methods for producing and applying the composition
IL230994A0 (en) Composition comprising a bmp protein, calcium phosphate and sodium bicarbonate for accelreation of bone growth and use of the composition in the preparation of a medicament
AU1515901A (en) Implant consisting of bone material
AU2001275253A1 (en) Orthopedic implant and method of making metal articles
AU2002357103A1 (en) Bioactive spinal implants and method of manufacture thereof
AU2001242349A1 (en) Inorganic resorbable bone substitute material and production method
AU2003279231A1 (en) Bone and tissue implants and method of making
AU2001245461A1 (en) Product and method for biological anchoring of connective tissue to bone
AU2001294994A1 (en) Cryogenic surgical system and method of use in removal of tissue
AU6379700A (en) Method of promoting bone growth with hyaluronic acid and growth factors
AU2003211140A1 (en) Composition and method for inducing bone growth and healing
HK1090633A1 (en) Process of preparing esters and ethers of probucol and derivatives thereof
AU2002331890A1 (en) Compositions and methods involved in bone growth
AU2002246849A1 (en) Agents and methods for promoting bone growth
IL156749A0 (en) Cutting and removal of biological tissue by pressurized propulsion of ice particles
AU2000251259A1 (en) Methods for promoting growth of bone, ligament, and cartilage using zvegf4
HK1039905A1 (en) Nanocomposite surgical materials and method of producing them
AU2003250448A1 (en) Method for the in vitro production of cartilage-like tissue
AU2003284691A1 (en) Calcium phosphate carrying protein, process for producing the same and sustained release protein preparation, artificial bone and tissue enginerring scaffold using the same
IL146892A0 (en) 3-dimensional in vitro models of mammalian tissue
WO2001059068A3 (en) Artificial bone chips, methods for the production thereof and their use