AU2001238540A1 - Non-aqueous injectable formulations for extended release of somatotropin - Google Patents

Non-aqueous injectable formulations for extended release of somatotropin

Info

Publication number
AU2001238540A1
AU2001238540A1 AU2001238540A AU3854001A AU2001238540A1 AU 2001238540 A1 AU2001238540 A1 AU 2001238540A1 AU 2001238540 A AU2001238540 A AU 2001238540A AU 3854001 A AU3854001 A AU 3854001A AU 2001238540 A1 AU2001238540 A1 AU 2001238540A1
Authority
AU
Australia
Prior art keywords
somatotropin
extended release
injectable formulations
aqueous injectable
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001238540A
Inventor
Yunhua N. Jeng
Kanaiyalal R. Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Technology LLC
Original Assignee
Monsanto Technology LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology LLC filed Critical Monsanto Technology LLC
Publication of AU2001238540A1 publication Critical patent/AU2001238540A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU2001238540A 2000-02-24 2001-02-20 Non-aqueous injectable formulations for extended release of somatotropin Abandoned AU2001238540A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18462500P 2000-02-24 2000-02-24
US60184625 2000-02-24
PCT/US2001/005408 WO2001062296A2 (en) 2000-02-24 2001-02-20 Non-aqueous injectable formulations for extended release of somatotropin

Publications (1)

Publication Number Publication Date
AU2001238540A1 true AU2001238540A1 (en) 2001-09-03

Family

ID=22677676

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001238540A Abandoned AU2001238540A1 (en) 2000-02-24 2001-02-20 Non-aqueous injectable formulations for extended release of somatotropin

Country Status (5)

Country Link
US (2) US6719990B2 (en)
KR (4) KR20090007504A (en)
AU (1) AU2001238540A1 (en)
MX (1) MXPA02008261A (en)
WO (1) WO2001062296A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030162711A1 (en) * 1996-04-24 2003-08-28 Soren Bjorn Pharmaceutical formulation
US20070179096A1 (en) * 1996-04-24 2007-08-02 Novo Nordisk A/S Pharmaceutical Formulation
JPWO2005073180A1 (en) * 2003-12-25 2008-01-10 株式会社クレハ Hydroxamic acid derivative and AGE production inhibitor containing the derivative
EA201692083A1 (en) 2014-04-16 2017-03-31 Вейкс-Фарма Гмбх PHARMACEUTICAL COMPOSITION FOR VETERINARY AND ITS APPLICATION
CN115501172A (en) 2014-11-21 2022-12-23 丹麦技术大学 Gel formulations for topical drug delivery

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474980A (en) * 1984-10-04 1995-12-12 Monsanto Company Prolonged release of biologically active somatotropins
KR890002631B1 (en) 1984-10-04 1989-07-21 몬산토 캄파니 Composition of prolonged release of biologically active somatotropin
US4861868A (en) 1985-02-22 1989-08-29 Monsanto Company Production of proteins in procaryotes
IL79681A (en) 1985-08-12 1991-06-10 Int Minerals & Chem Corp Transition metal complexes of growth hormones and their prolonged release compositions
US4977140A (en) 1985-08-23 1990-12-11 Eli Lilly And Company Injectable sustained release formulation
US5631227A (en) 1985-09-18 1997-05-20 The Upjohn Company Somatotropin analogs
US4917685A (en) * 1986-05-16 1990-04-17 International Minerals & Chem. Corp. Delivery device for the administration of stabilized growth promoting hormones
US4816568A (en) * 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
US4857506A (en) * 1987-01-12 1989-08-15 American Cyanamid Company Sustained release growth hormone compositions for parenteral administration and their use
DE3782737T3 (en) * 1987-08-21 1999-05-20 Imcera Group Inc Stabilization of growth hormones.
GB8725427D0 (en) * 1987-10-30 1987-12-02 Lilly Industries Ltd Somatotropin formulations
CA1331133C (en) * 1988-03-01 1994-08-02 Michael Jon Pikal Pharmaceutical growth hormone formulations
US5096885A (en) * 1988-04-15 1992-03-17 Genentech, Inc. Human growth hormone formulation
EP0374120A3 (en) * 1988-12-13 1991-07-31 Monsanto Company Comosition for controlled release of polypeptides
US5037420A (en) * 1988-12-13 1991-08-06 Alza Corporation Delivery system comprising two sections for delivering somatotropin
US5034229A (en) 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5219572A (en) 1989-03-17 1993-06-15 Pitman-Moore, Inc. Controlled release delivery device for macromolecular proteins
JP3009911B2 (en) * 1989-06-28 2000-02-14 エーザイ株式会社 Novel formulation of peptide or protein for internal use
AU653325B2 (en) 1990-02-12 1994-09-29 Lucky Limited A composition durably releasing bioactive polypeptides
US5182369A (en) 1990-02-28 1993-01-26 Monsanto Company Method for purifying somatotropin monomers
DE69209173T2 (en) 1991-06-24 1996-11-28 American Cyanamid Co Implantation compositions containing biologically active proteins, peptides or polypeptides
US5801141A (en) * 1991-06-24 1998-09-01 American Cyanamid Company Implant compositions containing a biologically active protein, peptide or polypeptide
ATE140620T1 (en) 1991-12-05 1996-08-15 Mallinckrodt Veterinary Inc GLASSY CARBOHYDRATE MATRICE FOR ADMINISTRATION OF DELAYED RELEASE MEDICATIONS
RO111990B1 (en) * 1991-12-20 1997-04-30 Novo Nordisk As Pharmaceutical preparations containing a raising hormone or one of its derivate and preparation process therefor
US5849704A (en) 1991-12-20 1998-12-15 Novo Nordisk A/S Pharmaceutical formulation
WO1993013792A1 (en) * 1992-01-13 1993-07-22 Pitman-Moore, Inc. Delayed release device for transition metal/protein complexes
JPH08502021A (en) 1992-04-07 1996-03-05 マリンクロッド・ヴェタラネリィ・インコーポレイテッド Biocompatible somatotropin solution
US5607691A (en) 1992-06-12 1997-03-04 Affymax Technologies N.V. Compositions and methods for enhanced drug delivery
US5359030A (en) 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
US5681811A (en) 1993-05-10 1997-10-28 Protein Delivery, Inc. Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
WO1995032222A1 (en) 1994-05-19 1995-11-30 Monsanto Company Method for purifying somatotropin monomers
US5904935A (en) 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
ZA965368B (en) 1995-07-14 1997-01-14 Novo Nordisk As A pharmaceutical formulation
KR100210509B1 (en) 1996-01-10 1999-07-15 성재갑 Composition for sustained release of animal growth hormone and method for preparation thereof
AUPN801296A0 (en) 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
US5912014A (en) 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
ZA9711731B (en) 1996-12-31 1998-07-01 Monsanto Co Aqueous glycerol formulations of somatotropin
EP0913177A1 (en) 1997-11-03 1999-05-06 Roche Diagnostics GmbH Process for producing dry, amorphous products comprising biological active materials by means of convection drying technique, especially spray drying
US6551613B1 (en) 1998-09-08 2003-04-22 Alza Corporation Dosage form comprising therapeutic formulation
US6162258A (en) 1999-08-25 2000-12-19 Osteotech, Inc. Lyophilized monolithic bone implant and method for treating bone

Also Published As

Publication number Publication date
WO2001062296A3 (en) 2002-05-30
KR100890679B1 (en) 2009-03-26
US7048938B2 (en) 2006-05-23
US20010046954A1 (en) 2001-11-29
MXPA02008261A (en) 2002-11-29
KR20070091373A (en) 2007-09-10
KR20020084136A (en) 2002-11-04
KR20080011353A (en) 2008-02-01
WO2001062296A2 (en) 2001-08-30
KR20090007504A (en) 2009-01-16
US6719990B2 (en) 2004-04-13
US20040171531A1 (en) 2004-09-02
KR100890125B1 (en) 2009-03-24

Similar Documents

Publication Publication Date Title
AU2001271491A1 (en) Non-aqueous surfactant-containing formulations for extended release of somatotropin
HK1216613A1 (en) Controlled release hydrocodone formulations
AU2002300377A1 (en) Compositions for controlled release
AU2001233738A1 (en) Improved paste formulations
HUP0203680A3 (en) Controlled release hydrocodone formulations
AU2001286233A1 (en) Cement composition
GB0218157D0 (en) Compositions for controlled release
AU2002248464A1 (en) Stabilized insulin formulations
GB0025208D0 (en) Delayed release pharmaceutical formulations
AU2002311766A1 (en) Stabilized ester peroxycarboxylic acid compositions
AU2001282617A1 (en) Compositions for external preparations
AU2002246666A1 (en) Anti-icing composition
AU2001297631A1 (en) Novel formulations of carvedilol
AU2001243611A1 (en) Stabilized dry powder formulations
SG84623A1 (en) Controlled release compositions
AU2001231042A1 (en) Optical measurements of bone composition
AU2001264264A1 (en) Sustained release compositions
AU5025300A (en) Compositions for controlled release of the hormone gnrh and its analogs
AU2001280870A1 (en) Aerosol solvent cement composition
AU2002222355A1 (en) Slag cement
AU2001238540A1 (en) Non-aqueous injectable formulations for extended release of somatotropin
AU2001267693A1 (en) Antiperspirant formulations
AU2001244108A1 (en) Formulations for states of dehydration
AU2001286996A1 (en) Stabilized fgf formulations containing reducing agents
AU2002226047A1 (en) Release agent composition