AU2001238533A1 - Detection of receptors for orphan ligands by retroviral display - Google Patents

Detection of receptors for orphan ligands by retroviral display

Info

Publication number
AU2001238533A1
AU2001238533A1 AU2001238533A AU3853301A AU2001238533A1 AU 2001238533 A1 AU2001238533 A1 AU 2001238533A1 AU 2001238533 A AU2001238533 A AU 2001238533A AU 3853301 A AU3853301 A AU 3853301A AU 2001238533 A1 AU2001238533 A1 AU 2001238533A1
Authority
AU
Australia
Prior art keywords
receptors
detection
retroviral display
orphan ligands
orphan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001238533A
Inventor
Mark P. Chadwick
Gerard J McGarrity
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CAMBRIDGE DRUG DISCOVERY Ltd
Original Assignee
CAMBRIDGE DRUG DISCOVERY Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CAMBRIDGE DRUG DISCOVERY Ltd filed Critical CAMBRIDGE DRUG DISCOVERY Ltd
Publication of AU2001238533A1 publication Critical patent/AU2001238533A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2001238533A 2000-02-25 2001-02-20 Detection of receptors for orphan ligands by retroviral display Abandoned AU2001238533A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18518800P 2000-02-25 2000-02-25
US60185188 2000-02-25
PCT/US2001/005388 WO2001062971A1 (en) 2000-02-25 2001-02-20 Detection of receptors for orphan ligands by retroviral display

Publications (1)

Publication Number Publication Date
AU2001238533A1 true AU2001238533A1 (en) 2001-09-03

Family

ID=22679968

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001238533A Abandoned AU2001238533A1 (en) 2000-02-25 2001-02-20 Detection of receptors for orphan ligands by retroviral display

Country Status (2)

Country Link
AU (1) AU2001238533A1 (en)
WO (1) WO2001062971A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1171638A4 (en) * 2000-02-25 2005-01-19 Biofocus Discovery Ltd Methods for identifying a protease inhibitor
JP2007526774A (en) * 2004-03-01 2007-09-20 ピーター・マッカラム・キャンサー・インスティテュート Recombinant perforin, its expression and its use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686592A (en) * 1990-06-11 1997-11-11 Nexstar Pharmaceuticals, Inc. High-affinity oligonucleotide ligands to immunoglobulin E (IgE)
US5834213A (en) * 1991-05-02 1998-11-10 Baylor College Of Medicine Screening system and assay for identifying compounds that regulate steroid and orphan receptors mediation of DNA transcription
US5766923A (en) * 1994-07-22 1998-06-16 President & Fellows Of Harvard College Isolated nucleic acid encoding ligands for FGFR

Also Published As

Publication number Publication date
WO2001062971A1 (en) 2001-08-30

Similar Documents

Publication Publication Date Title
AU2002210782A1 (en) Amide derivatives as nmda receptor antagonists
AU2002313616A1 (en) Peptide-based compounds for targeting intergin receptors
AU2708901A (en) Compounds exhibiting thrombopoietin receptor agonism
AU2003257172A1 (en) Cannabinoid receptor ligands
AU2002239639A1 (en) Seamless tiled display system
AU2002215100A1 (en) Imidazo-pyrimidine derivatives as ligands for gaba receptors
AU2002355266A1 (en) Analgesic methods using endothelin receptor ligands
EP1463759B8 (en) Ligand for g-protein coupled receptor gpr43 and uses thereof
AU2001238178A1 (en) Seven-transmembrane proteins/g-protein coupled receptors
AU3725600A (en) Surrogate orphan ligands for orphan receptors
AU2001258601A1 (en) Peptoids as ligands for melanocortin receptors
AU2001240097A1 (en) G protein-coupled receptors
AU2003294449A1 (en) Cannabinoid receptor ligands
AU2001270822A1 (en) Imidazolophthalazine derivatives as ligands for gabaa receptors
AU2001259051A1 (en) Piperidyindoles as serotonin receptor ligands
AU2001238533A1 (en) Detection of receptors for orphan ligands by retroviral display
AU2001210650A1 (en) Visual screening tests by means of computers
EP1286673B8 (en) Ligands of integrin receptors
AU2001281299A1 (en) Methods for automatically detecting gps hardware
AU2002255838A1 (en) Methods of detecting dissociated nuclear hormone receptor ligands
AU2002324727A1 (en) Mammalian relaxin receptors
AU2001249107A1 (en) Methods of assaying for g protein-coupled receptor ligands and modulators
AU2001249922A1 (en) G protein-coupled receptors
AU2002235543A1 (en) Imidazolophthalazine derivatives as ligands for gabaa receptors
AU2001242142A1 (en) Hetero-oligomeric g protein-coupled receptors as drug target