AU1821092A - New ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

New ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
AU1821092A
AU1821092A AU18210/92A AU1821092A AU1821092A AU 1821092 A AU1821092 A AU 1821092A AU 18210/92 A AU18210/92 A AU 18210/92A AU 1821092 A AU1821092 A AU 1821092A AU 1821092 A AU1821092 A AU 1821092A
Authority
AU
Australia
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
benzoate compounds
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU18210/92A
Other versions
AU646958B2 (en
Inventor
Michelle Boulanger
Jacques Duhault
Pierre Hugon
Francoise Lacour
Michel Wierzbicki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Publication of AU1821092A publication Critical patent/AU1821092A/en
Application granted granted Critical
Publication of AU646958B2 publication Critical patent/AU646958B2/en
Assigned to LES LABORATOIRES SERVIER reassignment LES LABORATOIRES SERVIER Alteration of Name(s) in Register under S187 Assignors: ADIR ET COMPAGNIE
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

New ethanolamine benzoate compounds, which can be used as medicaments and which correspond to the formula: <IMAGE> in which R is as defined in the description, in the racemic and enantiomeric forms. These new compounds and their physiologically tolerable salts can be used in therapeutics.
AU18210/92A 1991-06-14 1992-06-12 New ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them Ceased AU646958B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9107289 1991-06-14
FR9107289A FR2677647B1 (en) 1991-06-14 1991-06-14 NOVEL ETHANOLAMINE BENZOATE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Publications (2)

Publication Number Publication Date
AU1821092A true AU1821092A (en) 1992-12-17
AU646958B2 AU646958B2 (en) 1994-03-10

Family

ID=9413849

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18210/92A Ceased AU646958B2 (en) 1991-06-14 1992-06-12 New ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0518769B1 (en)
JP (1) JPH0669995B2 (en)
AT (1) ATE115118T1 (en)
AU (1) AU646958B2 (en)
CA (1) CA2071093C (en)
DE (1) DE69200810T2 (en)
DK (1) DK0518769T3 (en)
ES (1) ES2068011T3 (en)
FR (1) FR2677647B1 (en)
GR (1) GR3015212T3 (en)
HK (1) HK56797A (en)
IE (1) IE65634B1 (en)
NZ (1) NZ243116A (en)
ZA (1) ZA924312B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013605A1 (en) * 2001-08-07 2003-02-20 Japan Tobacco, Inc. Remedies for prostatic diseases
FR2834891B1 (en) * 2002-01-23 2004-02-27 Servier Lab ORODISPERSIBLE PHARMACEUTICAL COMPOSITION OF 2 - ({2-METHOXY-2- [3 (TRIFLUOROMETHYL) PHENYL] ETHYL} AMINO) ETHYL4 - (2- (9H-FLUOREN-9-YL) ACETYL] AMINO} ETHYL) BENZOATE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE320982B (en) * 1965-06-28 1970-02-23 Melville Sahyun Doing Business
GB1162070A (en) * 1967-06-12 1969-08-20 Science Union & Cie New Sulphamyl Benzoic Acid Derivatives and processes for preparing them
DE2629752A1 (en) * 1976-07-02 1978-01-05 Boehringer Mannheim Gmbh NEW CARBONIC ACID DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION
US4237165A (en) * 1976-06-04 1980-12-02 Science Union Et Cie Treatment of carbohydrate metabolism disorders
DE3260490D1 (en) * 1981-03-31 1984-09-06 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
FR2684101B1 (en) * 1991-11-22 1993-12-31 Adir Cie NOVEL ETHANOLAMINE BENZOATE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
GR3015212T3 (en) 1995-05-31
IE921903A1 (en) 1992-12-16
FR2677647A1 (en) 1992-12-18
ZA924312B (en) 1993-03-31
FR2677647B1 (en) 1993-08-20
EP0518769A1 (en) 1992-12-16
CA2071093A1 (en) 1992-12-15
CA2071093C (en) 1998-08-04
JPH0669995B2 (en) 1994-09-07
AU646958B2 (en) 1994-03-10
HK56797A (en) 1997-05-09
EP0518769B1 (en) 1994-12-07
NZ243116A (en) 1993-07-27
DE69200810T2 (en) 1995-07-06
IE65634B1 (en) 1995-11-01
DK0518769T3 (en) 1995-05-29
DE69200810D1 (en) 1995-01-19
JPH05238997A (en) 1993-09-17
ATE115118T1 (en) 1994-12-15
ES2068011T3 (en) 1995-04-01

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Legal Events

Date Code Title Description
PC Assignment registered

Owner name: LES LABORATOIRES SERVIER

Free format text: FORMER OWNER WAS: ADIR ET COMPAGNIE