AU1723001A - Methods and means for regulation of gene expression - Google Patents

Methods and means for regulation of gene expression

Info

Publication number
AU1723001A
AU1723001A AU17230/01A AU1723001A AU1723001A AU 1723001 A AU1723001 A AU 1723001A AU 17230/01 A AU17230/01 A AU 17230/01A AU 1723001 A AU1723001 A AU 1723001A AU 1723001 A AU1723001 A AU 1723001A
Authority
AU
Australia
Prior art keywords
regulation
methods
gene expression
gene
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU17230/01A
Inventor
Riccardo Cortese
Raffaele De Francesco
Petra Neddermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Original Assignee
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto di Ricerche di Biologia Molecolare P Angeletti SpA filed Critical Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Publication of AU1723001A publication Critical patent/AU1723001A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
AU17230/01A 1999-11-17 2000-11-17 Methods and means for regulation of gene expression Abandoned AU1723001A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9927191.8A GB9927191D0 (en) 1999-11-17 1999-11-17 Methods and means for regulation of gene expression
GB9927191 1999-11-17
PCT/IB2000/001828 WO2001036460A2 (en) 1999-11-17 2000-11-17 Methods and means for regulation of gene expression

Publications (1)

Publication Number Publication Date
AU1723001A true AU1723001A (en) 2001-05-30

Family

ID=10864679

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17230/01A Abandoned AU1723001A (en) 1999-11-17 2000-11-17 Methods and means for regulation of gene expression

Country Status (5)

Country Link
EP (1) EP1232271A2 (en)
AU (1) AU1723001A (en)
CA (1) CA2391971A1 (en)
GB (1) GB9927191D0 (en)
WO (1) WO2001036460A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20090946A1 (en) * 2009-05-28 2010-11-29 Novartis Ag EXPRESSION OF RECOMBINANT PROTEINS
US9428845B1 (en) 2010-12-28 2016-08-30 Warp Drive Bio, Inc. Identifying new therapeutic agents
TW201629069A (en) 2015-01-09 2016-08-16 霍普驅動生物科技股份有限公司 Compounds that participate in cooperative binding and uses thereof
EP3247378B8 (en) 2015-01-09 2023-08-23 Revolution Medicines, Inc. Macrocyclic compounds that participate in cooperative binding and medical uses thereof
EP3355930A4 (en) 2015-10-01 2019-03-06 Warp Drive Bio, Inc. Methods and reagents for analyzing protein-protein interfaces
EP3442599B1 (en) 2016-04-12 2022-03-30 Warp Drive Bio, Inc. Compositions and methods for the production of compounds
AU2017350900A1 (en) 2016-10-28 2019-06-13 Ginkgo Bioworks, Inc. Compositions and methods for the production of compounds
US11058725B2 (en) 2019-09-10 2021-07-13 Obsidian Therapeutics, Inc. CA2 compositions and methods for tunable regulation
WO2021091982A1 (en) 2019-11-04 2021-05-14 Revolution Medicines, Inc. Ras inhibitors
AU2020379731A1 (en) 2019-11-04 2022-05-05 Revolution Medicines, Inc. Ras inhibitors
MX2022005360A (en) 2019-11-04 2022-06-02 Revolution Medicines Inc Ras inhibitors.
CN117683049A (en) 2020-09-15 2024-03-12 锐新医药公司 Indole derivatives as RAS inhibitors for the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196318A (en) * 1990-06-26 1993-03-23 The Texas A&M University System Precisely regulated expression of deleterious genes
GB9311641D0 (en) * 1993-06-01 1993-07-21 Univ Warwick Process for activating gene expression in bacteria
GB9817704D0 (en) * 1998-08-13 1998-10-07 Zeneca Ltd Gene switch
EP1190079B1 (en) * 1999-07-01 2006-08-23 Calgene LLC Control of gene expression in eukaryotic cells

Also Published As

Publication number Publication date
CA2391971A1 (en) 2001-05-25
GB9927191D0 (en) 2000-01-12
WO2001036460A2 (en) 2001-05-25
WO2001036460A3 (en) 2002-01-03
EP1232271A2 (en) 2002-08-21

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase