AU1446601A - ((indol-3-yl)-cycloalkyl)-3-substituted azetidines for the treatment of central nervous system disorders - Google Patents

((indol-3-yl)-cycloalkyl)-3-substituted azetidines for the treatment of central nervous system disorders

Info

Publication number
AU1446601A
AU1446601A AU14466/01A AU1446601A AU1446601A AU 1446601 A AU1446601 A AU 1446601A AU 14466/01 A AU14466/01 A AU 14466/01A AU 1446601 A AU1446601 A AU 1446601A AU 1446601 A AU1446601 A AU 1446601A
Authority
AU
Australia
Prior art keywords
indol
cycloalkyl
treatment
nervous system
central nervous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14466/01A
Inventor
Magda Asselin
John Watson Ellingboe
Richard Eric Mewshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of AU1446601A publication Critical patent/AU1446601A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU14466/01A 1999-11-08 2000-10-31 ((indol-3-yl)-cycloalkyl)-3-substituted azetidines for the treatment of central nervous system disorders Abandoned AU1446601A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43611999A 1999-11-08 1999-11-08
US09436119 1999-11-08
PCT/US2000/029954 WO2001034598A1 (en) 1999-11-08 2000-10-31 [(indol-3-yl)-cycloalkyl]-3-substituted azetidines for the treatment of central nervous system disorders

Publications (1)

Publication Number Publication Date
AU1446601A true AU1446601A (en) 2001-06-06

Family

ID=23731187

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14466/01A Abandoned AU1446601A (en) 1999-11-08 2000-10-31 ((indol-3-yl)-cycloalkyl)-3-substituted azetidines for the treatment of central nervous system disorders

Country Status (8)

Country Link
EP (1) EP1228065A1 (en)
JP (1) JP2003513970A (en)
CN (1) CN1414962A (en)
AU (1) AU1446601A (en)
BR (1) BR0015401A (en)
CA (1) CA2390531A1 (en)
MX (1) MXPA02004555A (en)
WO (1) WO2001034598A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1638939A2 (en) * 2003-06-24 2006-03-29 Neurosearch A/S Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
PE20060373A1 (en) 2004-06-24 2006-04-29 Smithkline Beecham Corp 3-PIPERIDINYL-7-CARBOXAMIDE-INDAZOLE DERIVATIVES AS INHIBITORS OF IKK2 KINASE ACTIVITY
PE20060748A1 (en) 2004-09-21 2006-10-01 Smithkline Beecham Corp INDOLCARBOXAMIDE DERIVATIVES AS KINASE INHIBITORS IKK2
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
PE20081889A1 (en) 2007-03-23 2009-03-05 Smithkline Beecham Corp INDOL CARBOXAMIDES AS INHIBITORS OF IKK2
TW201033204A (en) 2008-12-10 2010-09-16 Janssen Pharmaceutica Nv 4-azetidinyl-1-heteroaryl-cyclohexanol antagonists of CCR2
JP2012520257A (en) 2009-03-10 2012-09-06 グラクソ グループ リミテッド Indole derivatives as IKK2 inhibitors
CN102459226B (en) 2009-04-17 2014-09-17 詹森药业有限公司 4-azetidinyl-1-heteroatom linked-cyclohexane antagonists of ccr2
WO2010121046A1 (en) 2009-04-17 2010-10-21 Janssen Pharmaceutica Nv 4-azetidinyl-1-phenyl-cyclohexane antagonists of ccr2
TW201211027A (en) * 2010-06-09 2012-03-16 Janssen Pharmaceutica Nv Cyclohexyl-azetidinyl antagonists of CCR2
TW201204717A (en) 2010-06-17 2012-02-01 Janssen Pharmaceutica Nv Cyclohexyl-azetidinyl antagonists of CCR2
CN116554168A (en) 2016-06-21 2023-08-08 X4 制药有限公司 CXCR4 inhibitors and uses thereof
CN109641838A (en) * 2016-06-21 2019-04-16 X4 制药有限公司 CXCR4 inhibitor and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9401436D0 (en) * 1994-01-26 1994-03-23 Wellcome Found Therapeutic heterocyclic compounds
PT1068184E (en) * 1998-04-08 2002-12-31 Wyeth Corp N-ARYLOXYETHYLAMINE DERIVATIVES FOR DEPRESSION TREATMENT
KR20010086163A (en) * 1999-01-07 2001-09-08 이곤 이 버그 Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression

Also Published As

Publication number Publication date
CA2390531A1 (en) 2001-05-17
WO2001034598A1 (en) 2001-05-17
BR0015401A (en) 2002-07-02
CN1414962A (en) 2003-04-30
JP2003513970A (en) 2003-04-15
EP1228065A1 (en) 2002-08-07
MXPA02004555A (en) 2004-09-10

Similar Documents

Publication Publication Date Title
AU2003249983A1 (en) Piperidines useful for the treatment of central nervous system disorders
IL143979A0 (en) Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression
AU2002212226A1 (en) Use of indole derivatives for treating illnesses of the central nervous system
AU7137000A (en) Electronic stimulation system for treating tinnitus disorders
EP1434801A4 (en) Treatment for central nervous system disorders
HU9803018D0 (en) Methods and compositions for the treatment and prevention of tumors, tumor-veloted disorders and cachexia
AU1446601A (en) ((indol-3-yl)-cycloalkyl)-3-substituted azetidines for the treatment of central nervous system disorders
IL155589A0 (en) Novel amidoalkyl-piperidine and amidoalkyl-piperazine derivatives useful for the treatment of nervous system disorders
AU6910600A (en) Methods for the treatment of mental disorders
ZA200107689B (en) 1-Arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives for the treatment of CNS disorders.
AU4674797A (en) Phenylalaninol derivatives for the treatment of central nervous system disorders
AU3086900A (en) Device for the complex treatment of disorders of the prostate
AU2384500A (en) Compounds, methods of screening and methods of treatment for central and peripheral nervous system disorders
AU2698697A (en) Azetidinone derivatives for the treatment of atherosclerosis
AU5042000A (en) Methods of treating proliferative disorders
AU2001271887A1 (en) Methods for diagnosis and treatment of psychiatric disorders
AU3745795A (en) Use of CCK-B receptor antagonists for the treatment of sleepdisorders
AU9763098A (en) Method for the treatment of disorders associated with apoptosis using n-heterocyclic glyoxylamide compounds
AU2002227895A1 (en) Sulphonamides for the treatment of central nervous system diseases
PL328228A1 (en) 1-(pyrazol-3-yl-ethyl)-4-(indol-3-yl)-piperidines as agents influencing the central nervous system
PL347329A1 (en) 3-tetrahydropyridin-4-yl indoles for treatment of psychotic disorders
EP1181308A4 (en) Methods for the treatment of neuronal atrophy-associated dementia
AU2080201A (en) Treatment of addiction disorders
AU5855899A (en) Method for identifying substances for the treatment of c-jun-mediated disorders
AU6007900A (en) Azetidine carboxamide derivatives for the treatment of cns disorders

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase