ATE99329T1 - Hydrogenierte derivate von antibiotika a/16686. - Google Patents
Hydrogenierte derivate von antibiotika a/16686.Info
- Publication number
- ATE99329T1 ATE99329T1 AT88119001T AT88119001T ATE99329T1 AT E99329 T1 ATE99329 T1 AT E99329T1 AT 88119001 T AT88119001 T AT 88119001T AT 88119001 T AT88119001 T AT 88119001T AT E99329 T1 ATE99329 T1 AT E99329T1
- Authority
- AT
- Austria
- Prior art keywords
- antibiotics
- tetrahydroderivatives
- hydrogenated derivatives
- factors
- hydrogenation
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- YRMCBQLZVBXOSJ-PCFSSPOYSA-N (e)-3-[(6r,6as)-4-hydroxy-6-methoxy-3-methyl-11-oxo-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-8-yl]prop-2-enamide Chemical compound CO[C@H]1NC2=C(O)C(C)=CC=C2C(=O)N2C=C(\C=C\C(N)=O)C[C@@H]12 YRMCBQLZVBXOSJ-PCFSSPOYSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 206010048038 Wound infection Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878729989A GB8729989D0 (en) | 1987-12-23 | 1987-12-23 | Novel hydrogenated derivatives of antibiotic a/16686 |
| EP88119001A EP0321696B1 (de) | 1987-12-23 | 1988-11-15 | Hydrogenierte Derivate von Antibiotika A/16686 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE99329T1 true ATE99329T1 (de) | 1994-01-15 |
Family
ID=10628943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88119001T ATE99329T1 (de) | 1987-12-23 | 1988-11-15 | Hydrogenierte derivate von antibiotika a/16686. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5108988A (de) |
| EP (1) | EP0321696B1 (de) |
| JP (1) | JP2507573B2 (de) |
| KR (1) | KR890009964A (de) |
| AT (1) | ATE99329T1 (de) |
| CA (1) | CA1338848C (de) |
| DE (1) | DE3886718T2 (de) |
| DK (1) | DK690288A (de) |
| ES (1) | ES2061610T3 (de) |
| GB (1) | GB8729989D0 (de) |
| IE (1) | IE883840L (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8621911D0 (en) * | 1986-09-11 | 1986-10-15 | Lepetit Spa | Increasing ratio of components of anti-biotic complex |
| GB8729989D0 (en) * | 1987-12-23 | 1988-02-03 | Lepetit Spa | Novel hydrogenated derivatives of antibiotic a/16686 |
| GB8808658D0 (en) * | 1988-04-13 | 1988-05-18 | Lepetit Spa | Aglycons of a/16686 antibiotics |
| CA2250578C (en) | 1996-04-23 | 2003-06-24 | Versicor Inc. | Improved chemical process for preparing amide derivatives of antibiotic a 40926 |
| EP0976394A1 (de) * | 1998-07-30 | 2000-02-02 | Biosearch Italia S.p.A. | Neue injizierbare Formulierungen |
| CA2476567A1 (en) * | 2002-03-08 | 2003-09-18 | Vicuron Pharmaceuticals Inc. | A process for the production of ramoplanin-like amide derivatives |
| US7317001B2 (en) | 2002-06-06 | 2008-01-08 | Oscient Pharmaceuticals Corporation | Use of ramoplanin to treat diseases associated with the use of antibiotics |
| AU2003274927A1 (en) * | 2002-08-23 | 2004-03-11 | Genome Therapeutics Corporation | Methods and reagents for preventing bacteremias |
| US20040127403A1 (en) * | 2002-09-06 | 2004-07-01 | Francesco Parenti | Methods for treating and preventing Gram-positive bacteremias |
| WO2004096143A2 (en) * | 2003-04-25 | 2004-11-11 | Oscient Pharmaceuticals Corporation | Methods for reducing or preventing transmission of nosocomial pathogens in a health care facility |
| US8252339B2 (en) * | 2006-04-11 | 2012-08-28 | Massachusetts Institute Of Technology | Medical treatment applications of swellable and deformable microspheres |
| EP2604619A3 (de) * | 2009-12-14 | 2014-01-22 | University of Basel | Mannosederivate als Antagonisten bakterieller Haftung |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA801629B (en) * | 1979-04-07 | 1981-03-25 | Lepetit Spa | Antibiotic a/16686 and process for the preparation thereof |
| EP0046201B1 (de) * | 1980-08-16 | 1984-04-11 | Gruppo Lepetit S.P.A. | Antibiotikum A/16686 Faktor A2, Verfahren zu dessen Herstellung und die gleichzeitig hergestellten Antibiotika A/16686 Faktoren A1 und A3 |
| GB8729989D0 (en) * | 1987-12-23 | 1988-02-03 | Lepetit Spa | Novel hydrogenated derivatives of antibiotic a/16686 |
-
1987
- 1987-12-23 GB GB878729989A patent/GB8729989D0/en active Pending
-
1988
- 1988-11-15 ES ES88119001T patent/ES2061610T3/es not_active Expired - Lifetime
- 1988-11-15 EP EP88119001A patent/EP0321696B1/de not_active Expired - Lifetime
- 1988-11-15 AT AT88119001T patent/ATE99329T1/de not_active IP Right Cessation
- 1988-11-15 DE DE88119001T patent/DE3886718T2/de not_active Expired - Fee Related
- 1988-12-05 US US07/280,035 patent/US5108988A/en not_active Expired - Lifetime
- 1988-12-12 DK DK690288A patent/DK690288A/da not_active Application Discontinuation
- 1988-12-22 IE IE883840A patent/IE883840L/xx unknown
- 1988-12-22 JP JP63322258A patent/JP2507573B2/ja not_active Expired - Fee Related
- 1988-12-22 KR KR1019880017157A patent/KR890009964A/ko not_active Application Discontinuation
- 1988-12-22 CA CA000586819A patent/CA1338848C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2507573B2 (ja) | 1996-06-12 |
| JPH01211600A (ja) | 1989-08-24 |
| DE3886718D1 (de) | 1994-02-10 |
| EP0321696B1 (de) | 1993-12-29 |
| IE883840L (en) | 1989-06-23 |
| US5108988A (en) | 1992-04-28 |
| ES2061610T3 (es) | 1994-12-16 |
| KR890009964A (ko) | 1989-08-05 |
| CA1338848C (en) | 1997-01-14 |
| DK690288A (da) | 1989-06-24 |
| EP0321696A2 (de) | 1989-06-28 |
| GB8729989D0 (en) | 1988-02-03 |
| DK690288D0 (da) | 1988-12-12 |
| EP0321696A3 (en) | 1990-07-11 |
| DE3886718T2 (de) | 1994-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |