ATE960T1 - DERIVATIVES OF 2-BENZOYL-4-NITRO-ANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES. - Google Patents

DERIVATIVES OF 2-BENZOYL-4-NITRO-ANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES.

Info

Publication number
ATE960T1
ATE960T1 AT80400942T AT80400942T ATE960T1 AT E960 T1 ATE960 T1 AT E960T1 AT 80400942 T AT80400942 T AT 80400942T AT 80400942 T AT80400942 T AT 80400942T AT E960 T1 ATE960 T1 AT E960T1
Authority
AT
Austria
Prior art keywords
group
nitrogen
anilides
benzoyl
nitro
Prior art date
Application number
AT80400942T
Other languages
German (de)
Inventor
Gilbert Mouzin
Henri Cousse
Original Assignee
Pierre Fabre S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre S.A. filed Critical Pierre Fabre S.A.
Application granted granted Critical
Publication of ATE960T1 publication Critical patent/ATE960T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1. New derivatives of 2-benzoyl-4-nitro-anilides corresponding to the following general formula : see diagramm : EP0022017,P12,F1 in which R represents a linear or branched alkyl group, an alkenyl group, a cycloalkyl group or a benzyl group ; R1 represents a hydrogen atom, an alkyl or hydroxy alkyl group ; R2 represents a hydroxy alkyl, alkenyl or alkynyl group optionally substituted once or several times by an alkyl radical or a cycloalkyl group containing from 3 to 6 carbon atoms ; R1 and R2 may in additon form with the nitrogen atom to which they are attached a nitrogen-containing heterocycle optionally containing a second heteroatom selected from oxygen and nitrogen ; with the proviso that, where R2 is a hydroxy alkyl group, R1 cannot be a hydrogen atom, and their salts obtained with therapeutically acceptable mineral or organic acids.
AT80400942T 1979-06-25 1980-06-24 DERIVATIVES OF 2-BENZOYL-4-NITRO-ANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES. ATE960T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7916213A FR2459793A1 (en) 1979-06-25 1979-06-25 NOVEL BENZOYL-2 NITRO-4 ANILIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
EP80400942A EP0022017B1 (en) 1979-06-25 1980-06-24 Derivatives of 2-benzoyl-4-nitro anilides, their preparation and their use as medicines

Publications (1)

Publication Number Publication Date
ATE960T1 true ATE960T1 (en) 1982-05-15

Family

ID=9227028

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80400942T ATE960T1 (en) 1979-06-25 1980-06-24 DERIVATIVES OF 2-BENZOYL-4-NITRO-ANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES.

Country Status (10)

Country Link
US (1) USRE31237E (en)
EP (1) EP0022017B1 (en)
JP (1) JPS568353A (en)
AT (1) ATE960T1 (en)
AU (1) AU536228B2 (en)
CA (1) CA1141380A (en)
DE (1) DE3060367D1 (en)
ES (1) ES493256A0 (en)
FR (1) FR2459793A1 (en)
ZA (1) ZA803721B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2436776A1 (en) 1978-09-25 1980-04-18 Fabre Sa Pierre NOVEL ORTHO CHLORO BENZOYL-2 CHLORO-4 GLYCYLANILIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR2525214B1 (en) * 1982-04-16 1986-02-07 Fabre Sa Pierre NOVEL HALOGENO BENZOYL-2 NITRO-4 GLYCYLANILIDES DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC APPLICATION THEREOF
FR2528424A1 (en) * 1982-06-11 1983-12-16 Fabre Sa Pierre Alpha-hydroxy-benzyl-glycyl-anilide(s) - for treatment of anxiety, prepd. boro:hydride redn. of benzoyl-glycyl-anilide
JP2711034B2 (en) * 1991-09-25 1998-02-10 大日本スクリーン製造株式会社 Photosensitive plate storage and transport device
US6063921A (en) 1997-11-20 2000-05-16 Pharm-Eco Laboratories, Inc. Synthesis of 11-aryl-5,6-dihydro-11H-dibenz[b,e]azepines
PL364144A1 (en) 2001-02-05 2004-12-13 Amcol International Corporation Multifunctional particulate additive for personal care and cosmetic compositions, and the process of making the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1462887A (en) * 1966-01-06 1966-12-16 Hoffmann La Roche Process for the preparation of benzodiazepine derivatives
US3914215A (en) * 1967-11-27 1975-10-21 Sankyo Co Benzodiazepine derivatives and process for preparing the same
BG19177A3 (en) * 1968-07-01 1975-04-30 Sankyo Co Ltd BENZODIAZEPINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
US3799928A (en) * 1970-09-18 1974-03-26 L Schlager 3-amino alkyl-4-phenyl-2(1h)-quinolone derivatives
AT314541B (en) * 1970-10-19 1974-04-10 Sumitomo Chemical Co Process for the production of new benzodiazepines and their salts
LU65340A1 (en) * 1972-05-12 1973-11-22
DE2356239A1 (en) * 1973-11-10 1975-05-15 Cassella Farbwerke Mainkur Ag BENZOPHENONE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
JPS52113952A (en) * 1976-03-19 1977-09-24 Shionogi & Co Ltd Aminobenzophenone derivatives
FR2403330A1 (en) * 1977-06-16 1979-04-13 Fabre Sa Pierre NEW DERIVATIVES OF BENZOYL-2-CHLORO-4-GLYCINANILIDES SUBSTITUTES, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Also Published As

Publication number Publication date
ZA803721B (en) 1981-07-29
FR2459793A1 (en) 1981-01-16
FR2459793B1 (en) 1983-09-09
JPS568353A (en) 1981-01-28
USRE31237E (en) 1983-05-10
ES8104199A1 (en) 1981-04-16
AU5953180A (en) 1981-01-08
EP0022017A1 (en) 1981-01-07
AU536228B2 (en) 1984-05-03
CA1141380A (en) 1983-02-15
ES493256A0 (en) 1981-04-16
EP0022017B1 (en) 1982-05-05
DE3060367D1 (en) 1982-06-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee