ATE9154T1 - 5,6,6a-7-tetrahydro-4h-di benz(de,g)isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen die sie enthalten. - Google Patents
5,6,6a-7-tetrahydro-4h-di benz(de,g)isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen die sie enthalten.Info
- Publication number
- ATE9154T1 ATE9154T1 AT81301271T AT81301271T ATE9154T1 AT E9154 T1 ATE9154 T1 AT E9154T1 AT 81301271 T AT81301271 T AT 81301271T AT 81301271 T AT81301271 T AT 81301271T AT E9154 T1 ATE9154 T1 AT E9154T1
- Authority
- AT
- Austria
- Prior art keywords
- carbon atoms
- tetrahydro
- branched
- straight
- compounds
- Prior art date
Links
- AWJUIBRHMBBTKR-UHFFFAOYSA-N iso-quinoline Natural products C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000002537 isoquinolines Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- -1 phenoxy, benzyloxy Chemical group 0.000 abstract 2
- ZCEUIMSAZXGXIZ-UHFFFAOYSA-N 4,5,15-trimethoxy-11-methyl-11-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2,4,6,13,15-hexaen-16-ol Chemical compound C1N(C)CC2=CC(OC)=C(O)C3=C2C1CC1=C3C=C(OC)C(OC)=C1 ZCEUIMSAZXGXIZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803013346 DE3013346A1 (de) | 1980-04-05 | 1980-04-05 | Dibenz(de,g)isochinolin-derivate, verfahren zu deren herstellung, diese enthaltende arzneimittel sowie deren verwendung bei der bekaempfung von erkrankungen des zentralen nervensystems |
| EP81301271A EP0042659B1 (de) | 1980-04-05 | 1981-03-25 | 5,6,6a-7-Tetrahydro-4H-dibenz(de,g)isochinolinderivate, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen die sie enthalten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE9154T1 true ATE9154T1 (de) | 1984-09-15 |
Family
ID=6099404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81301271T ATE9154T1 (de) | 1980-04-05 | 1981-03-25 | 5,6,6a-7-tetrahydro-4h-di benz(de,g)isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen die sie enthalten. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4425350A (de) |
| EP (1) | EP0042659B1 (de) |
| JP (1) | JPS579763A (de) |
| AT (1) | ATE9154T1 (de) |
| DE (2) | DE3013346A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3118521A1 (de) * | 1981-05-09 | 1982-12-02 | Gödecke AG, 1000 Berlin | Dibenzo(de,g)chinolin-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von erkaeltungskrankheiten und allergien |
| US4543256A (en) * | 1982-03-17 | 1985-09-24 | Northeastern University | (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers |
| JP3509941B2 (ja) * | 1994-07-27 | 2004-03-22 | 富士写真フイルム株式会社 | データ検索方法およびその装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3920820A (en) * | 1972-04-20 | 1975-11-18 | Ayerst Mckenna & Harrison | Benzocycloheptaisoquinoline derivatives iii |
| US3950344A (en) | 1973-09-13 | 1976-04-13 | The University Of Virginia | Non-phenol oxidative coupling |
-
1980
- 1980-04-05 DE DE19803013346 patent/DE3013346A1/de not_active Withdrawn
-
1981
- 1981-03-25 DE DE8181301271T patent/DE3165731D1/de not_active Expired
- 1981-03-25 AT AT81301271T patent/ATE9154T1/de not_active IP Right Cessation
- 1981-03-25 EP EP81301271A patent/EP0042659B1/de not_active Expired
- 1981-04-03 US US06/251,000 patent/US4425350A/en not_active Expired - Fee Related
- 1981-04-04 JP JP5006981A patent/JPS579763A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4425350A (en) | 1984-01-10 |
| JPS579763A (en) | 1982-01-19 |
| EP0042659A1 (de) | 1981-12-30 |
| EP0042659B1 (de) | 1984-08-29 |
| DE3013346A1 (de) | 1981-10-15 |
| DE3165731D1 (en) | 1984-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |