ATE86254T1 - Verfahren zur synthese eines benzo(ij>chinolizin- 2-carbonsaeure-derivates. - Google Patents
Verfahren zur synthese eines benzo(ij>chinolizin- 2-carbonsaeure-derivates.Info
- Publication number
- ATE86254T1 ATE86254T1 AT88115302T AT88115302T ATE86254T1 AT E86254 T1 ATE86254 T1 AT E86254T1 AT 88115302 T AT88115302 T AT 88115302T AT 88115302 T AT88115302 T AT 88115302T AT E86254 T1 ATE86254 T1 AT E86254T1
- Authority
- AT
- Austria
- Prior art keywords
- quinolizine
- benzo
- fluoro
- methyl
- alkyl
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- -1 2,2-disubstituted 1,3-dioxan-4,6-dione Chemical class 0.000 abstract 2
- DPSPPJIUMHPXMA-UHFFFAOYSA-N 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid Chemical compound C1CC(C)N2C=C(C(O)=O)C(=O)C3=C2C1=CC(F)=C3 DPSPPJIUMHPXMA-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- GOCWCDOCXBSXIT-UHFFFAOYSA-N 2-methylidene-1,3-dioxane-4,6-dione Chemical compound C=C1OC(=O)CC(=O)O1 GOCWCDOCXBSXIT-UHFFFAOYSA-N 0.000 abstract 1
- BDCCXYVTXRUGAN-UHFFFAOYSA-N 6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline Chemical compound FC1=CC=C2NC(C)CCC2=C1 BDCCXYVTXRUGAN-UHFFFAOYSA-N 0.000 abstract 1
- 229920000388 Polyphosphate Polymers 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229960000702 flumequine Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000001205 polyphosphate Substances 0.000 abstract 1
- 235000011176 polyphosphates Nutrition 0.000 abstract 1
- 229920000137 polyphosphoric acid Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8722142A IT1231425B (it) | 1987-10-05 | 1987-10-05 | Procedimento per la sintesi di un derivato dell'acido benzo (ij) chinolizin-2-carbossilico |
| EP88115302A EP0310849B1 (de) | 1987-10-05 | 1988-09-19 | Verfahren zur Synthese eines Benzo[ij]chinolizin-2-carbonsäure-Derivates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE86254T1 true ATE86254T1 (de) | 1993-03-15 |
Family
ID=11192115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88115302T ATE86254T1 (de) | 1987-10-05 | 1988-09-19 | Verfahren zur synthese eines benzo(ij>chinolizin- 2-carbonsaeure-derivates. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0310849B1 (de) |
| JP (1) | JPH01128982A (de) |
| AT (1) | ATE86254T1 (de) |
| DE (1) | DE3878814T2 (de) |
| IT (1) | IT1231425B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2655545B1 (fr) * | 1989-12-11 | 1994-06-10 | Rhone Poulenc Sante | Nouvelle application therapeutique des derives des fluoroquinolones. |
| US5532239A (en) * | 1993-08-02 | 1996-07-02 | Assistance Publique - Hopitaux De Paris | Therapeutic application of fluoroquinolone derivatives |
| US20070197548A1 (en) | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
| US7973022B2 (en) | 2006-02-17 | 2011-07-05 | Idexx Laboratories, Inc. | Fluoroquinolone carboxylic acid salt compositions |
| US8485403B2 (en) | 2008-03-27 | 2013-07-16 | GM Global Technology Operations LLC | Roof rack assembly with stowable cross members |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2476079A1 (fr) * | 1980-02-19 | 1981-08-21 | Riker Laboratories Inc | Nouveaux derives tetrahydroquinaldiniques, leur procede de preparation et leur utilisation dans la production de flumequine |
-
1987
- 1987-10-05 IT IT8722142A patent/IT1231425B/it active
-
1988
- 1988-09-19 DE DE8888115302T patent/DE3878814T2/de not_active Expired - Fee Related
- 1988-09-19 EP EP88115302A patent/EP0310849B1/de not_active Expired - Lifetime
- 1988-09-19 AT AT88115302T patent/ATE86254T1/de not_active IP Right Cessation
- 1988-10-04 JP JP63249176A patent/JPH01128982A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0310849B1 (de) | 1993-03-03 |
| DE3878814T2 (de) | 1993-06-09 |
| EP0310849A1 (de) | 1989-04-12 |
| IT8722142A0 (it) | 1987-10-05 |
| DE3878814D1 (de) | 1993-04-08 |
| JPH01128982A (ja) | 1989-05-22 |
| IT1231425B (it) | 1991-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |