ATE851T1 - HYDROXYETHYL-AZOLES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS. - Google Patents

HYDROXYETHYL-AZOLES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS.

Info

Publication number
ATE851T1
ATE851T1 AT79104484T AT79104484T ATE851T1 AT E851 T1 ATE851 T1 AT E851T1 AT 79104484 T AT79104484 T AT 79104484T AT 79104484 T AT79104484 T AT 79104484T AT E851 T1 ATE851 T1 AT E851T1
Authority
AT
Austria
Prior art keywords
hydroxyethyl
azoles
processes
production
medicinal products
Prior art date
Application number
AT79104484T
Other languages
German (de)
Inventor
Erik Ing. Grad. Regel
Karl Heinz Prof. Dr. Buechel
Ingo Dr. Haller
Manfred Dr. Plempel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE851T1 publication Critical patent/ATE851T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to hydroxyethyl-azole compounds and methods for their preparation. Also included in the invention are compositions containing said hydroxyethyl-azole compounds and methods for the use of said compounds and compositions as antimycotic agents.
AT79104484T 1978-11-25 1979-11-14 HYDROXYETHYL-AZOLES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS. ATE851T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782851116 DE2851116A1 (en) 1978-11-25 1978-11-25 HYDROXYETHYL AZOLE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
EP79104484A EP0011769B1 (en) 1978-11-25 1979-11-14 Hydroxyethyl azoles, process for their preparation and their use in medicaments

Publications (1)

Publication Number Publication Date
ATE851T1 true ATE851T1 (en) 1982-04-15

Family

ID=6055583

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79104484T ATE851T1 (en) 1978-11-25 1979-11-14 HYDROXYETHYL-AZOLES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS.

Country Status (18)

Country Link
US (1) US4301166A (en)
EP (1) EP0011769B1 (en)
JP (1) JPS5573662A (en)
AT (1) ATE851T1 (en)
AU (1) AU534447B2 (en)
CA (1) CA1128528A (en)
DD (1) DD148219A5 (en)
DE (2) DE2851116A1 (en)
DK (1) DK499579A (en)
ES (1) ES486280A1 (en)
FI (1) FI65993C (en)
HU (1) HU179415B (en)
IE (1) IE48881B1 (en)
IL (1) IL58775A (en)
NO (1) NO793674L (en)
NZ (1) NZ192196A (en)
PH (1) PH15562A (en)
ZA (1) ZA796357B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927839A (en) * 1979-03-07 1990-05-22 Imperial Chemical Industries Plc Method of preventing fungal attack on wood, hides, leather or paint films using a triazole
US4551469A (en) * 1979-03-07 1985-11-05 Imperial Chemical Industries Plc Antifungal triazole ethanol derivatives
US4654332A (en) * 1979-03-07 1987-03-31 Imperial Chemical Industries Plc Heterocyclic compounds
DE2912288A1 (en) * 1979-03-28 1980-10-09 Bayer Ag METHOD FOR PRODUCING HYDROXYETHYL AZOLES
GB2069481B (en) * 1980-02-13 1983-07-27 Farmos Oy Substituted imidazole derivatives
US5395942A (en) * 1980-06-02 1995-03-07 Zeneca Limited Heterocyclic compounds
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
EP0047594A3 (en) * 1980-08-18 1982-06-09 Imperial Chemical Industries Plc Triazole compounds, a process for preparing them, their use as plant fungicides and plant growth regulators and compositions containing them
IE51533B1 (en) * 1980-08-28 1987-01-07 Ici Ltd Pharmaceutical compositions of fungicidal triazole derivatives
US4479004A (en) * 1980-11-03 1984-10-23 Janssen Pharmaceutica N.V. 1-[2-(4-Diphenyl)-1,3-dioxolan-2-yl-methyl]-1-H-triazoles
DE3106635A1 (en) * 1981-02-23 1982-09-09 Bayer Ag ANTIMYCOTIC AGENT WITH HIGH ACTIVE SUBSTANCE RELEASE IN THE FORM OF PEN
US5466821A (en) * 1981-03-18 1995-11-14 Zeneca Limited Heterocyclic compounds
DE3111238A1 (en) * 1981-03-21 1982-10-07 Bayer Ag, 5090 Leverkusen SUBSTITUTED TRIAZOLYL METHYL OXIRANES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS INTERMEDIATE PRODUCTS
AU8314482A (en) * 1981-05-19 1982-11-25 Imperial Chemical Industries Plc 3-triazolyl(imidazolyl)-2,2 bis phenyl-propionamides
JPS5815909A (en) * 1981-07-22 1983-01-29 Toko Yakuhin Kogyo Kk Antimycotic agent for external use
DE3245504A1 (en) * 1982-12-09 1984-06-14 Bayer Ag, 5090 Leverkusen FUNGICIDES, THEIR PRODUCTION AND USE
US4610716A (en) * 1982-12-14 1986-09-09 Ciba-Geigy Corporation Fluorinated azolyl ethanol growth regulators and microbicides
US4624958A (en) * 1983-04-14 1986-11-25 Pfizer Inc. Antiprotozoal 1,4-di(p-amidinophenyl)imidazoles
US4766140A (en) * 1984-06-18 1988-08-23 Eli Lilly And Company Method of inhibiting aromatase
US4729986A (en) * 1986-04-24 1988-03-08 E. I. Du Pont De Nemours And Company Fungicidal triazoles and imidazoles
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
US5006513A (en) * 1987-11-09 1991-04-09 Miles Inc. Antimycotic compositions of nikkomycin compounds and azole antimycotica
US5096889A (en) * 1987-11-09 1992-03-17 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
US4914087A (en) * 1988-02-29 1990-04-03 Bayer Ag Nikkomycin derivatives, antimycotic compositions of nikkomycin derivatives and azole antimycotics
US4859693A (en) * 1988-08-10 1989-08-22 E. I. Du Pont De Nemours And Company Antiinflammatory carbinoloimidazoles
US5049570A (en) * 1990-01-23 1991-09-17 Du Pont Merck Pharmaceutical Company Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity
DE4027608A1 (en) * 1990-08-31 1992-03-05 Bayer Ag METHOD FOR PRODUCING 1-CHLOR-2- (1-CHLORO-CYCLOPROPYL) -3- (2-CHLORO-PHENYL) -PROPAN-2-OL AND / OR 2- (1-CHLORO-CYCLOPROPYL) -2- (2 -CHLORINE-BENZYL) -OXIRANE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2431407C2 (en) * 1974-06-29 1982-12-02 Bayer Ag, 5090 Leverkusen 1,2,4-Triazol-1-yl-alkanones and alkanols, processes for their preparation and their use as fungicides
GB1569267A (en) * 1975-12-16 1980-06-11 Ici Ltd Substituted propiophenones and herbicidal and fungicidal compositions containing them
DE2623129C3 (en) * 1976-05-22 1980-04-10 Nordmark-Werke Gmbh, 2000 Hamburg U-Diphenyl-3- (imidazol-1-yl) -propan-2-ols, process for their preparation and pharmaceuticals containing them

Also Published As

Publication number Publication date
FI65993C (en) 1984-08-10
DE2962527D1 (en) 1982-05-27
AU534447B2 (en) 1984-02-02
FI793689A (en) 1980-05-26
IL58775A (en) 1984-02-29
HU179415B (en) 1982-10-28
PH15562A (en) 1983-02-11
NZ192196A (en) 1981-04-24
FI65993B (en) 1984-04-30
EP0011769A1 (en) 1980-06-11
EP0011769B1 (en) 1982-04-14
NO793674L (en) 1980-05-28
US4301166A (en) 1981-11-17
ZA796357B (en) 1980-12-31
IE48881B1 (en) 1985-06-12
DE2851116A1 (en) 1980-06-12
ES486280A1 (en) 1980-05-16
IE792242L (en) 1980-05-25
DK499579A (en) 1980-05-26
JPS5573662A (en) 1980-06-03
AU5317379A (en) 1980-05-29
DD148219A5 (en) 1981-05-13
JPS638939B2 (en) 1988-02-25
CA1128528A (en) 1982-07-27
IL58775A0 (en) 1980-02-29

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