ATE82771T1 - MODULATION OF ANIMAL CELLULAR RESPONSE USING PREPARATIONS CONTAINING ISOXANTHOPTERIN-8-(1'BETA-ALDOGLYKOSIDYL) DERIVATIVES. - Google Patents

MODULATION OF ANIMAL CELLULAR RESPONSE USING PREPARATIONS CONTAINING ISOXANTHOPTERIN-8-(1'BETA-ALDOGLYKOSIDYL) DERIVATIVES.

Info

Publication number
ATE82771T1
ATE82771T1 AT87900549T AT87900549T ATE82771T1 AT E82771 T1 ATE82771 T1 AT E82771T1 AT 87900549 T AT87900549 T AT 87900549T AT 87900549 T AT87900549 T AT 87900549T AT E82771 T1 ATE82771 T1 AT E82771T1
Authority
AT
Austria
Prior art keywords
isoxanthopterin
aldoglykosidyl
beta
modulation
derivatives
Prior art date
Application number
AT87900549T
Other languages
German (de)
Inventor
Michael G Goodman
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Application granted granted Critical
Publication of ATE82771T1 publication Critical patent/ATE82771T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants

Abstract

Animal cellular responses, and particularly immune-related responses, are modulated by contacting such cells with a unit dose of a composition containing an effective amount of an isoxanthopterin-8-aldoglycoside. An isoxanthopterin has a structure that conforms to formula (I), wherein R1 is a substituent and R2 is an aldoglycoside.
AT87900549T 1985-12-13 1986-12-12 MODULATION OF ANIMAL CELLULAR RESPONSE USING PREPARATIONS CONTAINING ISOXANTHOPTERIN-8-(1'BETA-ALDOGLYKOSIDYL) DERIVATIVES. ATE82771T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80888685A 1985-12-13 1985-12-13
PCT/US1986/002716 WO1987003617A1 (en) 1985-12-13 1986-12-12 Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-beta-aldoglycosidyl) derivatives
EP87900549A EP0248084B1 (en) 1985-12-13 1986-12-12 Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-beta-aldoglycosidyl) derivatives

Publications (1)

Publication Number Publication Date
ATE82771T1 true ATE82771T1 (en) 1992-12-15

Family

ID=25200016

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87900549T ATE82771T1 (en) 1985-12-13 1986-12-12 MODULATION OF ANIMAL CELLULAR RESPONSE USING PREPARATIONS CONTAINING ISOXANTHOPTERIN-8-(1'BETA-ALDOGLYKOSIDYL) DERIVATIVES.

Country Status (15)

Country Link
EP (1) EP0248084B1 (en)
JP (1) JPS63502113A (en)
AT (1) ATE82771T1 (en)
AU (1) AU592848B2 (en)
CA (1) CA1300506C (en)
DE (1) DE3687169T2 (en)
DK (1) DK598986A (en)
ES (1) ES2003179A6 (en)
FI (1) FI873496A0 (en)
GR (1) GR862901B (en)
IL (1) IL80928A (en)
NZ (1) NZ218618A (en)
PT (1) PT83921B (en)
WO (1) WO1987003617A1 (en)
ZA (1) ZA869297B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880784A (en) * 1987-12-21 1989-11-14 Brigham Young University Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
AU635339B2 (en) * 1989-10-11 1993-03-18 Merrell Dow Pharmaceuticals Inc. Inosine/guanosine derivatives as immunosuppressive agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081410B1 (en) * 1970-01-06 1974-08-23 Ciba Geigy Ag
JPS5399319A (en) * 1977-02-09 1978-08-30 Hidematsu Hirai Novel qualitative and quantitative detecting method and detecting body for antgenic substance
JPS57200862A (en) * 1981-06-05 1982-12-09 Fuji Photo Film Co Ltd Mutilayer analysis element utilizing unique binding reaction
US4435504A (en) * 1982-07-15 1984-03-06 Syva Company Immunochromatographic assay with support having bound "MIP" and second enzyme
US4643992A (en) * 1982-11-09 1987-02-17 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
GB8305197D0 (en) * 1983-02-24 1983-03-30 Amersham Int Plc Assay methods

Also Published As

Publication number Publication date
FI873496A (en) 1987-08-12
DK598986A (en) 1987-06-14
AU592848B2 (en) 1990-01-25
IL80928A (en) 1992-08-18
WO1987003617A1 (en) 1987-06-18
EP0248084A4 (en) 1988-03-30
GR862901B (en) 1987-04-15
DE3687169D1 (en) 1993-01-07
IL80928A0 (en) 1987-03-31
PT83921A (en) 1987-01-01
ZA869297B (en) 1987-11-25
NZ218618A (en) 1989-03-29
EP0248084B1 (en) 1992-11-25
CA1300506C (en) 1992-05-12
EP0248084A1 (en) 1987-12-09
DK598986D0 (en) 1986-12-12
PT83921B (en) 1989-01-17
JPS63502113A (en) 1988-08-18
DE3687169T2 (en) 1993-04-01
ES2003179A6 (en) 1988-10-16
FI873496A0 (en) 1987-08-12
AU6848287A (en) 1987-06-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee