ATE81777T1 - Gefriergetrocknete pulverfoermige cyclophosphamidzusammensetzung sowie verfahren zu deren herstellung. - Google Patents

Gefriergetrocknete pulverfoermige cyclophosphamidzusammensetzung sowie verfahren zu deren herstellung.

Info

Publication number
ATE81777T1
ATE81777T1 AT90201352T AT90201352T ATE81777T1 AT E81777 T1 ATE81777 T1 AT E81777T1 AT 90201352 T AT90201352 T AT 90201352T AT 90201352 T AT90201352 T AT 90201352T AT E81777 T1 ATE81777 T1 AT E81777T1
Authority
AT
Austria
Prior art keywords
freeze
cyclophosphamide
dried powder
powder composition
same manufacture
Prior art date
Application number
AT90201352T
Other languages
English (en)
Inventor
Alfred James Nijkerk
Johanna Maria Pieterne Vermeer
Original Assignee
Pharmachemie Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv
Application granted granted Critical
Publication of ATE81777T1 publication Critical patent/ATE81777T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT90201352T 1989-06-06 1990-05-28 Gefriergetrocknete pulverfoermige cyclophosphamidzusammensetzung sowie verfahren zu deren herstellung. ATE81777T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8901431A NL8901431A (nl) 1989-06-06 1989-06-06 Gevriesdroogd, poedervormig cyclofosfamidepreparaat, alsmede werkwijze ter bereiding daarvan.
EP90201352A EP0401894B1 (de) 1989-06-06 1990-05-28 Gefriergetrocknete pulverförmige Cyclophosphamidzusammensetzung sowie Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ATE81777T1 true ATE81777T1 (de) 1992-11-15

Family

ID=19854783

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90201352T ATE81777T1 (de) 1989-06-06 1990-05-28 Gefriergetrocknete pulverfoermige cyclophosphamidzusammensetzung sowie verfahren zu deren herstellung.

Country Status (4)

Country Link
EP (1) EP0401894B1 (de)
AT (1) ATE81777T1 (de)
DE (1) DE69000412D1 (de)
NL (1) NL8901431A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2001552C (en) * 1988-11-14 1997-07-22 The Upjohn Company Cyclophosphamide - sodium bicarbonate lyophilizates
US5418223A (en) * 1993-05-20 1995-05-23 Erbamont, Inc. Method for lyophilization of cyclophosphamide and product
US6613927B1 (en) * 2002-02-08 2003-09-02 American Pharmaceutical Partners, Inc. Sterile lyophilized ifosfamide and associated methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide
US4659699A (en) * 1983-08-22 1987-04-21 Cetus-Ben Venue Therapeutics Process for freeze drying cyclophosphamide

Also Published As

Publication number Publication date
EP0401894A1 (de) 1990-12-12
NL8901431A (nl) 1991-01-02
DE69000412D1 (de) 1992-12-03
EP0401894B1 (de) 1992-10-28

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