ATE81772T1 - Kovalent gebundene mittel mit kohlenstoffionengruppen. - Google Patents

Kovalent gebundene mittel mit kohlenstoffionengruppen.

Info

Publication number
ATE81772T1
ATE81772T1 AT87906338T AT87906338T ATE81772T1 AT E81772 T1 ATE81772 T1 AT E81772T1 AT 87906338 T AT87906338 T AT 87906338T AT 87906338 T AT87906338 T AT 87906338T AT E81772 T1 ATE81772 T1 AT E81772T1
Authority
AT
Austria
Prior art keywords
compositions
covalently bonded
active agents
base groups
carbon ion
Prior art date
Application number
AT87906338T
Other languages
English (en)
Inventor
Robert F Helwing
Original Assignee
Robert F Helwing
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert F Helwing filed Critical Robert F Helwing
Application granted granted Critical
Publication of ATE81772T1 publication Critical patent/ATE81772T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
AT87906338T 1986-09-26 1987-09-03 Kovalent gebundene mittel mit kohlenstoffionengruppen. ATE81772T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/912,352 US4842868A (en) 1986-09-26 1986-09-26 Covalently bonded active agents with carbonium ion base groups
EP87906338A EP0321499B1 (de) 1986-09-26 1987-09-03 Kovalent gebundene mittel mit kohlenstoffionen-gruppen
PCT/US1987/002228 WO1988002252A1 (en) 1986-09-26 1987-09-03 Covalently bonded active agents with carbonium ion base groups
CA000574727A CA1321577C (en) 1986-09-26 1988-08-15 Covalently bonded active agents with carbonium ion base groups

Publications (1)

Publication Number Publication Date
ATE81772T1 true ATE81772T1 (de) 1992-11-15

Family

ID=25672052

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87906338T ATE81772T1 (de) 1986-09-26 1987-09-03 Kovalent gebundene mittel mit kohlenstoffionengruppen.

Country Status (7)

Country Link
US (1) US4842868A (de)
EP (1) EP0321499B1 (de)
AT (1) ATE81772T1 (de)
AU (1) AU614498B2 (de)
CA (1) CA1321577C (de)
DE (1) DE3782434T2 (de)
WO (1) WO1988002252A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5456904A (en) * 1993-06-28 1995-10-10 The Procter & Gamble Company Photoprotection compositions comprising certain chelating agents
US20050152950A1 (en) * 1995-11-13 2005-07-14 Saffran Bruce N. Method and apparatus for macromolecular delivery using a coated membrane
CA2822457C (en) 2001-12-14 2016-03-08 The University Of Wyoming Methods and compositions for controlled resease of drugs
US9050393B2 (en) 2005-02-08 2015-06-09 Bruce N. Saffran Medical devices and methods for modulation of physiology using device-based surface chemistry
GB0908781D0 (en) 2009-05-21 2009-07-01 Cadbury Uk Ltd Confectionery product
US20250263285A1 (en) * 2024-02-16 2025-08-21 Kelli Daniella Brown Oak Variable Capacity Tank Lid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304767A (en) * 1980-05-15 1981-12-08 Sri International Polymers of di- (and higher functionality) ketene acetals and polyols
US4532335A (en) * 1983-03-07 1985-07-30 Sri International Preparation of ketene acetals by rearrangement of allyl and substituted allyl acetals
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
GB8430252D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof

Also Published As

Publication number Publication date
EP0321499A4 (de) 1990-04-10
AU8032587A (en) 1988-04-21
DE3782434D1 (de) 1992-12-03
DE3782434T2 (de) 1993-03-11
US4842868A (en) 1989-06-27
CA1321577C (en) 1993-08-24
WO1988002252A1 (en) 1988-04-07
AU614498B2 (en) 1991-09-05
EP0321499B1 (de) 1992-10-28
EP0321499A1 (de) 1989-06-28

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties