ATE8143T1 - 3,4-dihydroxyphenyltetrahydrothienopyridine. - Google Patents

3,4-dihydroxyphenyltetrahydrothienopyridine.

Info

Publication number
ATE8143T1
ATE8143T1 AT81302247T AT81302247T ATE8143T1 AT E8143 T1 ATE8143 T1 AT E8143T1 AT 81302247 T AT81302247 T AT 81302247T AT 81302247 T AT81302247 T AT 81302247T AT E8143 T1 ATE8143 T1 AT E8143T1
Authority
AT
Austria
Prior art keywords
dihydroxyphenyltetrahydrothienopyridine
dihydroxyphenyltetrahydrothieno
tetrahydrothieno
thienylmethyl
dihydroxyphenyl
Prior art date
Application number
AT81302247T
Other languages
English (en)
Inventor
Martin L. Brenner
Original Assignee
Smithkline Beckman Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corporation filed Critical Smithkline Beckman Corporation
Application granted granted Critical
Publication of ATE8143T1 publication Critical patent/ATE8143T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT81302247T 1980-05-22 1981-05-21 3,4-dihydroxyphenyltetrahydrothienopyridine. ATE8143T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/152,253 US4282227A (en) 1980-05-22 1980-05-22 Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines
EP81302247A EP0040955B1 (de) 1980-05-22 1981-05-21 3,4-Dihydroxyphenyltetrahydrothienopyridine

Publications (1)

Publication Number Publication Date
ATE8143T1 true ATE8143T1 (de) 1984-07-15

Family

ID=22542144

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81302247T ATE8143T1 (de) 1980-05-22 1981-05-21 3,4-dihydroxyphenyltetrahydrothienopyridine.

Country Status (5)

Country Link
US (1) US4282227A (de)
EP (1) EP0040955B1 (de)
JP (1) JPS5716884A (de)
AT (1) ATE8143T1 (de)
DE (1) DE3164412D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71661A0 (en) * 1983-04-27 1984-07-31 Boehringer Ingelheim Kg 4-phenyl-tetrahydro-furano-pyridines,their preparation and pharmaceutical compositions containing them
US4876261A (en) * 1987-03-27 1989-10-24 Akihiro Tanaka Substituted tetrahydroisoquinoline compounds and composition containing them
DE69432217T2 (de) * 1993-04-06 2004-04-08 Abbott Laboratories, Abbott Park Tetracyclische verbindungen als dopamin-agonisten
US5668141A (en) * 1996-04-02 1997-09-16 Abbott Laboratories Trans-2,6-,3,6-and 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzo[c]phenanthrene compounds as dopamine agonists
WO2003070245A1 (en) * 2002-02-15 2003-08-28 Darpharma, Inc. Mono-ester and asymmetrically substituted di-ester pro-drugs of the dopamine d1 receptor agonists
CN102391244A (zh) * 2011-09-21 2012-03-28 天津理工大学 一种3-取代胺甲基噻吩化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3520895A (en) * 1968-02-16 1970-07-21 Colgate Palmolive Co 1-substituted-1,2,3,4-tetrahydrobenzothieno(2,3-c)pyridines
FR2358150A1 (fr) * 1976-07-13 1978-02-10 Parcor Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application
FR2423494A1 (fr) * 1977-06-02 1979-11-16 Parcor Benzo (b) thieno pyridines, leur procede de preparation et leurs applications therapeutiques
AT368504B (de) * 1977-10-15 1982-10-25 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine
DE2746443C2 (de) * 1977-10-15 1986-09-18 C.H. Boehringer Sohn, 6507 Ingelheim 4-Phenyl-thieno-[2,3-c]-piperidine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Also Published As

Publication number Publication date
US4282227A (en) 1981-08-04
EP0040955B1 (de) 1984-06-27
EP0040955A2 (de) 1981-12-02
DE3164412D1 (en) 1984-08-02
JPS5716884A (en) 1982-01-28
EP0040955A3 (en) 1982-01-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee