ATE75053T1 - Immunotest fuer biologisch wirksames menschliches interferon-gamma. - Google Patents
Immunotest fuer biologisch wirksames menschliches interferon-gamma.Info
- Publication number
- ATE75053T1 ATE75053T1 AT85900850T AT85900850T ATE75053T1 AT E75053 T1 ATE75053 T1 AT E75053T1 AT 85900850 T AT85900850 T AT 85900850T AT 85900850 T AT85900850 T AT 85900850T AT E75053 T1 ATE75053 T1 AT E75053T1
- Authority
- AT
- Austria
- Prior art keywords
- gamma
- biologically active
- huifn
- human interferon
- immunotest
- Prior art date
Links
- 101000599940 Homo sapiens Interferon gamma Proteins 0.000 title abstract 6
- 102000043557 human IFNG Human genes 0.000 title abstract 6
- 238000003556 assay Methods 0.000 abstract 2
- 238000003018 immunoassay Methods 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 238000012875 competitive assay Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000003127 radioimmunoassay Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6866—Interferon
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/570,353 US4666865A (en) | 1984-01-13 | 1984-01-13 | Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies |
PCT/US1985/000026 WO1985003133A1 (en) | 1984-01-13 | 1985-01-10 | Immunoassay for biologically active human interferon-gamma |
EP85900850A EP0169234B1 (de) | 1984-01-13 | 1985-01-10 | Immunotest für biologisch wirksames menschliches interferon-gamma |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE75053T1 true ATE75053T1 (de) | 1992-05-15 |
Family
ID=24279325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT85900850T ATE75053T1 (de) | 1984-01-13 | 1985-01-10 | Immunotest fuer biologisch wirksames menschliches interferon-gamma. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4666865A (de) |
EP (1) | EP0169234B1 (de) |
JP (1) | JPS61501164A (de) |
AT (1) | ATE75053T1 (de) |
CA (1) | CA1242658A (de) |
DE (1) | DE3585853D1 (de) |
WO (1) | WO1985003133A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2584418B1 (fr) * | 1985-07-05 | 1988-11-10 | Unicet Laboratoires | Anticorps monoclonaux contre le g-interferon, hybridomes produisant de tels anticorps, procede de preparation de tels anticorps et de tels hybridomes, leur utilisation pour differencier les gifs, et ensemble ou " kit " utilisant de tels anticorps |
WO1987005400A1 (en) * | 1986-03-06 | 1987-09-11 | Commonwealth Scientific And Industrial Research Or | In vitro assay for detecting cell-mediated immune responses |
DE3642096A1 (de) * | 1986-12-10 | 1988-06-16 | Boehringer Ingelheim Int | Pferde-(gamma)-interferon |
CA1335792C (en) * | 1987-08-18 | 1995-06-06 | Chaim O. Jacob | Method and dosage form using an antagonist to gamma interferon to control mhc-associated autoimmune disease |
US5830709A (en) * | 1989-10-27 | 1998-11-03 | Benson; Roger E. | Detection method for homologous portions of a class of substances |
US5196311A (en) * | 1989-10-27 | 1993-03-23 | Health Research, Incorporated | Elisa test for von willebrand factor |
US5202264A (en) * | 1989-10-27 | 1993-04-13 | Health Research, Incorporated | ELISA using multi-species antibodies for detection of von Willebrand factor in multiple species |
WO2001019989A2 (en) * | 1999-09-14 | 2001-03-22 | Entremed, Inc. | Method of producing and purifying endostatintm protein |
WO2002097440A2 (de) * | 2001-05-29 | 2002-12-05 | Reinhold Kiehl | Verfahren zur bestimmung von peptiden/proteinen, massenspektrometrie für metalle und leitfähigkeitsfeststellung |
US7084257B2 (en) * | 2001-10-05 | 2006-08-01 | Amgen Inc. | Fully human antibody Fab fragments with human interferon-gamma neutralizing activity |
WO2004004643A2 (en) * | 2002-07-03 | 2004-01-15 | The Brighamn And Women's Hospital, Inc. | Interferon gamma in the detection and treatment of angiomyolipomas |
WO2005118884A1 (en) * | 2004-05-28 | 2005-12-15 | The United States Of America As Represented By The Secretary Of The Navy | A method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines |
JP5006800B2 (ja) * | 2005-01-17 | 2012-08-22 | ユィロス・パテント・アクチボラグ | 二つの親和性反応物を用いて、少なくとも二価のアナライトを検出する方法 |
EP3827020A1 (de) | 2018-07-24 | 2021-06-02 | Amgen Inc. | Kombination von inhibitoren des lilrb1/2-signalwegs und pd-1-signalwegs |
CN109781972B (zh) * | 2019-01-16 | 2022-02-18 | 深圳大学 | 一种免疫定量检测方法和应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS604423B2 (ja) * | 1976-12-15 | 1985-02-04 | 持田製薬株式会社 | ペプチドホルモンの定量方法 |
WO1981002899A1 (en) * | 1980-04-11 | 1981-10-15 | D Secher | Monoclonal antibody |
US4423147A (en) * | 1980-04-11 | 1983-12-27 | Secher David S | Monoclonal antibody to interferon-α |
US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
SE8006424L (sv) * | 1980-09-12 | 1982-03-13 | Jolla Cancer Res Found | Sett att bestemma ett antigen i losning |
JPS5767858A (en) * | 1980-10-15 | 1982-04-24 | Takeda Chem Ind Ltd | Immunochemical measurement method for human chorionic gonadotropin and production of antibody |
WO1982001773A1 (en) * | 1980-11-07 | 1982-05-27 | Secher David S | Assay for interferon |
WO1982002661A1 (en) * | 1981-01-30 | 1982-08-19 | Inc Centocor | Immunoassay for multi-determinant antigens |
ES511156A0 (es) * | 1981-04-13 | 1983-08-01 | Hoechst Co American | Un metodo de determinar la presencia de un antigeno en un medio liquido sospechoso de contenerlo. |
CA1209907A (en) * | 1982-04-12 | 1986-08-19 | Richard M. Bartholomew | Method of affinity purification employing monoclonal antibodies |
US4514505A (en) * | 1982-05-21 | 1985-04-30 | The Trustees Of Columbia University In The City Of New York | Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays |
US4474892A (en) * | 1983-02-16 | 1984-10-02 | Board Of Trustees Of The Leland Stanford Junior University | Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same |
FR2755603B1 (fr) * | 1996-11-12 | 1999-02-26 | Jacques Preaut | Ensemble d'ancillaires pour la pose de cotyles de protheses de hanche, et ensemble prothetique de cotyle pret a etre pose |
-
1984
- 1984-01-13 US US06/570,353 patent/US4666865A/en not_active Expired - Fee Related
-
1985
- 1985-01-10 JP JP60500516A patent/JPS61501164A/ja active Pending
- 1985-01-10 DE DE8585900850T patent/DE3585853D1/de not_active Expired - Lifetime
- 1985-01-10 EP EP85900850A patent/EP0169234B1/de not_active Expired - Lifetime
- 1985-01-10 AT AT85900850T patent/ATE75053T1/de not_active IP Right Cessation
- 1985-01-10 WO PCT/US1985/000026 patent/WO1985003133A1/en active IP Right Grant
- 1985-01-11 CA CA000471957A patent/CA1242658A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
WO1985003133A1 (en) | 1985-07-18 |
EP0169234A1 (de) | 1986-01-29 |
JPS61501164A (ja) | 1986-06-12 |
CA1242658A (en) | 1988-10-04 |
DE3585853D1 (de) | 1992-05-21 |
EP0169234B1 (de) | 1992-04-15 |
US4666865A (en) | 1987-05-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |