ATE74000T1 - Dihydroergotamin-(d.h.e.)-tablette des typs hydrophile matrix und verfahren zu ihrer herstellung. - Google Patents
Dihydroergotamin-(d.h.e.)-tablette des typs hydrophile matrix und verfahren zu ihrer herstellung.Info
- Publication number
- ATE74000T1 ATE74000T1 AT88400340T AT88400340T ATE74000T1 AT E74000 T1 ATE74000 T1 AT E74000T1 AT 88400340 T AT88400340 T AT 88400340T AT 88400340 T AT88400340 T AT 88400340T AT E74000 T1 ATE74000 T1 AT E74000T1
- Authority
- AT
- Austria
- Prior art keywords
- dihydroergotamine
- tablet
- type
- hydrophilic matrix
- production
- Prior art date
Links
- HESHRHUZIWVEAJ-JGRZULCMSA-N dihydroergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2[C@@H](C3=CC=CC4=NC=C([C]34)C2)C1)C)C1=CC=CC=C1 HESHRHUZIWVEAJ-JGRZULCMSA-N 0.000 title abstract 2
- 229960004704 dihydroergotamine Drugs 0.000 title abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 2
- 230000008961 swelling Effects 0.000 abstract 2
- 239000007970 homogeneous dispersion Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8702076A FR2610827B1 (fr) | 1987-02-18 | 1987-02-18 | Comprime de dihydroergotamine (d.h.e.) du type a matrice hydrophile et son procede de fabrication |
| EP88400340A EP0280613B1 (de) | 1987-02-18 | 1988-02-16 | Dihydroergotamin-(D.H.E.)-Tablette des Typs hydrophile Matrix und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE74000T1 true ATE74000T1 (de) | 1992-04-15 |
Family
ID=9348044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88400340T ATE74000T1 (de) | 1987-02-18 | 1988-02-16 | Dihydroergotamin-(d.h.e.)-tablette des typs hydrophile matrix und verfahren zu ihrer herstellung. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0280613B1 (de) |
| JP (1) | JPS63203617A (de) |
| AT (1) | ATE74000T1 (de) |
| CA (1) | CA1340660C (de) |
| DE (1) | DE3869443D1 (de) |
| ES (1) | ES2037254T3 (de) |
| FR (1) | FR2610827B1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2653337B1 (fr) * | 1989-10-23 | 1992-02-07 | Dow Corning Sa | Element a liberation prolongee et procede pour le fabriquer. |
| US6210710B1 (en) * | 1997-04-28 | 2001-04-03 | Hercules Incorporated | Sustained release polymer blend for pharmaceutical applications |
| HRP20010700B1 (hr) | 1999-03-31 | 2011-01-31 | Janssen Pharmaceutica N.V. | Prezelatinizirani skrob u formulaciji s kontroliranim otpustanjem |
| RU2162324C1 (ru) * | 1999-11-23 | 2001-01-27 | Аметов Александр Сергеевич | Способ фармакологического лечения психогенной эректильной дисфункции |
| RU2256454C2 (ru) * | 1999-12-03 | 2005-07-20 | Полишем С.А. | Способы получения фармацевтических композиций алкалоидов спорыньи с пролонгированным действием, характеризующихся улучшенной биодоступностью, и содержащие указанные алкалоиды композиции |
| US7771746B2 (en) | 1999-12-03 | 2010-08-10 | Polichem Sa | Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof |
| TWI338583B (en) | 2004-05-20 | 2011-03-11 | Otsuka Pharma Co Ltd | Solid pharmaceutical formulation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2546577B2 (de) * | 1975-10-17 | 1981-04-02 | Sandoz-Patent-GmbH, 7850 Lörrach | Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden |
| US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
| US4652442A (en) * | 1983-07-05 | 1987-03-24 | Arcana Chem. Pharm. Fabrik Gesellschaft M.B.H. | Process of producing a sustained release preparation containing indomethacin or niomethacin |
| HU195729B (en) * | 1985-02-05 | 1988-07-28 | Sandoz Ag | Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides |
| US4608248A (en) * | 1985-11-08 | 1986-08-26 | Warner-Lambert Company | Process for time-controlled release of active ingredients |
-
1987
- 1987-02-18 FR FR8702076A patent/FR2610827B1/fr not_active Expired - Lifetime
-
1988
- 1988-02-16 AT AT88400340T patent/ATE74000T1/de not_active IP Right Cessation
- 1988-02-16 EP EP88400340A patent/EP0280613B1/de not_active Expired - Lifetime
- 1988-02-16 DE DE8888400340T patent/DE3869443D1/de not_active Expired - Lifetime
- 1988-02-16 ES ES198888400340T patent/ES2037254T3/es not_active Expired - Lifetime
- 1988-02-17 CA CA000559169A patent/CA1340660C/fr not_active Expired - Fee Related
- 1988-02-18 JP JP63034114A patent/JPS63203617A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA1340660C (fr) | 1999-07-20 |
| JPS63203617A (ja) | 1988-08-23 |
| DE3869443D1 (de) | 1992-04-30 |
| FR2610827B1 (fr) | 1991-09-13 |
| EP0280613B1 (de) | 1992-03-25 |
| EP0280613A1 (de) | 1988-08-31 |
| FR2610827A1 (fr) | 1988-08-19 |
| ES2037254T3 (es) | 1993-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |