ATE67760T1 - In stellung 2 substituierte monoaryl-5 astriazinone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. - Google Patents
In stellung 2 substituierte monoaryl-5 astriazinone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.Info
- Publication number
- ATE67760T1 ATE67760T1 AT87400094T AT87400094T ATE67760T1 AT E67760 T1 ATE67760 T1 AT E67760T1 AT 87400094 T AT87400094 T AT 87400094T AT 87400094 T AT87400094 T AT 87400094T AT E67760 T1 ATE67760 T1 AT E67760T1
- Authority
- AT
- Austria
- Prior art keywords
- image
- substituted
- astriazinones
- preparation
- bond
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- YEJRWHAVMIAJKC-UHFFFAOYSA-N 4-Butyrolactone Chemical compound O=C1CCCO1 YEJRWHAVMIAJKC-UHFFFAOYSA-N 0.000 abstract 2
- -1 acetonyloxy Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000003187 heptyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8600552A FR2592878B1 (fr) | 1986-01-16 | 1986-01-16 | Monoaryl-5 as triazinones-3 substituees en position 2, leur procede de preparation et leur application en tant que medicaments |
| EP87400094A EP0233804B1 (de) | 1986-01-16 | 1987-01-16 | In Stellung 2 substituierte Monoaryl-5 as-Triazinone, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE67760T1 true ATE67760T1 (de) | 1991-10-15 |
Family
ID=9331167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87400094T ATE67760T1 (de) | 1986-01-16 | 1987-01-16 | In stellung 2 substituierte monoaryl-5 astriazinone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4851411A (de) |
| EP (1) | EP0233804B1 (de) |
| JP (1) | JPH01117875A (de) |
| AT (1) | ATE67760T1 (de) |
| AU (1) | AU597327B2 (de) |
| CA (1) | CA1294279C (de) |
| DE (1) | DE3773223D1 (de) |
| ES (1) | ES2040265T3 (de) |
| FR (1) | FR2592878B1 (de) |
| GR (1) | GR3002823T3 (de) |
| ZA (1) | ZA87306B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5021415A (en) * | 1990-02-13 | 1991-06-04 | Bristol-Myers Squibb Co. | Triazine carboxylic acids and esters |
| CA2036192A1 (en) | 1990-02-13 | 1991-08-14 | Nicholas Meanwell | Heterocyclic carboxylic acids and esters |
| EP3549935A4 (de) * | 2016-11-30 | 2020-08-05 | Mitsubishi Tanabe Pharma Corporation | Verfahren zur herstellung von triazinverbindungen |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3428635A (en) * | 1966-12-05 | 1969-02-18 | Dow Chemical Co | Substituted 1,4,5,6 - tetrahydro - as - triazines and a method for their production |
| EP0052442B1 (de) * | 1980-11-14 | 1985-09-11 | Imperial Chemical Industries Plc | Heterocyclische Derivate |
| CA1199027A (en) * | 1981-11-12 | 1986-01-07 | Stuart D. Mills | Heterocyclic derivatives of pyridazinone, thiadiazinone, oxadiazinone and triazinone |
| EP0099438A1 (de) * | 1982-07-20 | 1984-02-01 | Pierre Fabre S.A. | 2-Funktionalisierte Diaryl-as-triazine anwendbar in Therapie |
| FR2544313B1 (fr) * | 1983-04-14 | 1985-08-09 | Fabre Sa Pierre | Les n-cycloalcoyl methyl-2 oxo-3 diaryl 5-6 as triazines, leur procede de fabrication et leur utilisation en tant que medicament |
-
1986
- 1986-01-16 FR FR8600552A patent/FR2592878B1/fr not_active Expired
-
1987
- 1987-01-15 AU AU67595/87A patent/AU597327B2/en not_active Ceased
- 1987-01-15 US US07/004,169 patent/US4851411A/en not_active Expired - Fee Related
- 1987-01-16 AT AT87400094T patent/ATE67760T1/de not_active IP Right Cessation
- 1987-01-16 ES ES198787400094T patent/ES2040265T3/es not_active Expired - Lifetime
- 1987-01-16 JP JP62006294A patent/JPH01117875A/ja active Pending
- 1987-01-16 CA CA000527511A patent/CA1294279C/fr not_active Expired - Fee Related
- 1987-01-16 DE DE8787400094T patent/DE3773223D1/de not_active Expired - Fee Related
- 1987-01-16 EP EP87400094A patent/EP0233804B1/de not_active Expired - Lifetime
- 1987-01-30 ZA ZA87306A patent/ZA87306B/xx unknown
-
1991
- 1991-09-30 GR GR91401458T patent/GR3002823T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01117875A (ja) | 1989-05-10 |
| ES2040265T3 (es) | 1993-10-16 |
| FR2592878A1 (fr) | 1987-07-17 |
| GR3002823T3 (en) | 1993-01-25 |
| AU597327B2 (en) | 1990-05-31 |
| EP0233804A1 (de) | 1987-08-26 |
| AU6759587A (en) | 1987-07-23 |
| EP0233804B1 (de) | 1991-09-25 |
| DE3773223D1 (de) | 1991-10-31 |
| ZA87306B (en) | 1987-09-30 |
| CA1294279C (fr) | 1992-01-14 |
| US4851411A (en) | 1989-07-25 |
| FR2592878B1 (fr) | 1988-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |