ATE66534T1 - Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung. - Google Patents

Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung.

Info

Publication number
ATE66534T1
ATE66534T1 AT85303601T AT85303601T ATE66534T1 AT E66534 T1 ATE66534 T1 AT E66534T1 AT 85303601 T AT85303601 T AT 85303601T AT 85303601 T AT85303601 T AT 85303601T AT E66534 T1 ATE66534 T1 AT E66534T1
Authority
AT
Austria
Prior art keywords
methods
determination
conjugates
antibodies
enzymes
Prior art date
Application number
AT85303601T
Other languages
English (en)
Inventor
Mae Wan-Leng Hu
Prithipal Singh
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of ATE66534T1 publication Critical patent/ATE66534T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9466—Antidepressants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
AT85303601T 1984-05-23 1985-05-22 Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung. ATE66534T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/613,709 US4795822A (en) 1984-05-23 1984-05-23 Nortriptyline conjugates to antigenic proteins and enzymes
EP85303601A EP0167256B1 (de) 1984-05-23 1985-05-22 Nortriptylinderivate, Verfahren zu ihrer Herstellung, deren Konjugate mit antigenischen Proteinen und Enzymen, Antikörper davon und verwandte Verfahren zur Bestimmung

Publications (1)

Publication Number Publication Date
ATE66534T1 true ATE66534T1 (de) 1991-09-15

Family

ID=24458404

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85303601T ATE66534T1 (de) 1984-05-23 1985-05-22 Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung.

Country Status (6)

Country Link
US (1) US4795822A (de)
EP (1) EP0167256B1 (de)
JP (3) JPH0689039B2 (de)
AT (1) ATE66534T1 (de)
CA (1) CA1279592C (de)
DE (1) DE3583830D1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601141A1 (fr) * 1986-07-02 1988-01-08 Centre Nat Rech Scient Produit de couplage a base d'haptene, utile notamment comme substance immunogene, anticorps correspondants et applications
US5407835A (en) * 1991-07-31 1995-04-18 Abbott Laboratories Reagents and methods for the quantification of amitriptyline or nortriptyline in biological fluids
US6803040B1 (en) * 1995-08-22 2004-10-12 Biosite, Inc. Derivatives of tricyclic antidepressants and protein and polypeptide tricyclic antidepressant derivative conjugates and labels
US6368814B1 (en) * 2000-12-22 2002-04-09 Roche Diagnostics Corporation Tricyclic antidepressant derivatives and immunoassay

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2412700A (en) * 1944-06-10 1946-12-17 Eastman Kodak Co Thioglycolic amides
FR1368709A (fr) * 1959-10-27 1964-08-07 Merck & Co Inc Dérivés du dibenzo [a, d] [1, 4] cycloheptadiène
DE1468341A1 (de) * 1963-07-25 1969-05-22 Merck & Co Inc Dibenzocycloheptan- und -hepten-Verbindungen und Verfahren zu ihrer Herstellung
CA890423A (en) * 1968-11-08 1972-01-11 A. Davis Martin Process for preparing dibenzo (a,d)-cycloheptene derivatives
CA875549A (en) * 1968-12-03 1971-07-13 Ayerst, Mckenna And Harrison Limited Process for preparing amitriptyline and related compounds
CH541545A (de) * 1970-10-09 1973-09-15 Hoffmann La Roche Verfahren zur Herstellung von tricyclischen Iminen
US4329502A (en) * 1978-08-28 1982-05-11 Syva Company Propranolol antigen conjugates and antibodies
US4241177A (en) * 1978-08-28 1980-12-23 Syva Company Propanolol antigen conjugates and antibodies
US4307245A (en) * 1978-12-29 1981-12-22 Syva Company Amitriptyline conjugates to antigenic proteins and enzymes
US4223013A (en) * 1978-12-29 1980-09-16 Syva Company Amitriptyline conjugates to antigenic proteins and enzymes
US4495281A (en) * 1982-10-21 1985-01-22 Miles Laboratories, Inc. Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives

Also Published As

Publication number Publication date
JPH0689039B2 (ja) 1994-11-09
DE3583830D1 (de) 1991-09-26
JPH08105894A (ja) 1996-04-23
JP2609083B2 (ja) 1997-05-14
JPS6141A (ja) 1986-01-06
EP0167256A1 (de) 1986-01-08
JP2526359B2 (ja) 1996-08-21
JPH06201694A (ja) 1994-07-22
CA1279592C (en) 1991-01-29
US4795822A (en) 1989-01-03
EP0167256B1 (de) 1991-08-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee