ATE59653T1 - Trans-benzopyran-(4,3-b>-1,4-oxazinderivate. - Google Patents
Trans-benzopyran-(4,3-b>-1,4-oxazinderivate.Info
- Publication number
- ATE59653T1 ATE59653T1 AT87107345T AT87107345T ATE59653T1 AT E59653 T1 ATE59653 T1 AT E59653T1 AT 87107345 T AT87107345 T AT 87107345T AT 87107345 T AT87107345 T AT 87107345T AT E59653 T1 ATE59653 T1 AT E59653T1
- Authority
- AT
- Austria
- Prior art keywords
- benzopyran
- trans
- derivates
- oxazine
- alkyl
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940052760 dopamine agonists Drugs 0.000 abstract 1
- 239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003518 presynaptic effect Effects 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/865,306 US4792548A (en) | 1986-05-21 | 1986-05-21 | Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use |
| EP87107345A EP0246633B1 (de) | 1986-05-21 | 1987-05-20 | Trans-Benzopyran-[4,3-b]-1,4-oxazinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE59653T1 true ATE59653T1 (de) | 1991-01-15 |
Family
ID=25345191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87107345T ATE59653T1 (de) | 1986-05-21 | 1987-05-20 | Trans-benzopyran-(4,3-b>-1,4-oxazinderivate. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4792548A (de) |
| EP (1) | EP0246633B1 (de) |
| JP (1) | JPS62283978A (de) |
| AT (1) | ATE59653T1 (de) |
| CA (1) | CA1283104C (de) |
| DE (1) | DE3766884D1 (de) |
| ES (1) | ES2031850T3 (de) |
| GR (1) | GR3001494T3 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2721027B1 (fr) | 1994-06-08 | 1996-07-19 | Adir | Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
| FR2741074B1 (fr) | 1995-11-09 | 1997-12-19 | Adir | Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO2020210785A1 (en) | 2019-04-12 | 2020-10-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | D3 receptor agonist compounds; methods of preparation; intermediates thereof; and methods of use thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0080117B1 (de) * | 1981-11-20 | 1987-12-02 | Merck & Co. Inc. | Das (R,R)-Enantiomere von trans-Indeno(1,2-b)-1,4-oxazinen, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zusammensetzungen |
| ATE64735T1 (de) * | 1984-05-10 | 1991-07-15 | Ciba Geigy Ag | Benzo-(pyrano und thiopyrano)-pyridine. |
-
1986
- 1986-05-21 US US06/865,306 patent/US4792548A/en not_active Expired - Fee Related
-
1987
- 1987-04-24 CA CA000535535A patent/CA1283104C/en not_active Expired - Fee Related
- 1987-05-20 DE DE8787107345T patent/DE3766884D1/de not_active Expired - Fee Related
- 1987-05-20 JP JP62121441A patent/JPS62283978A/ja active Pending
- 1987-05-20 EP EP87107345A patent/EP0246633B1/de not_active Expired - Lifetime
- 1987-05-20 AT AT87107345T patent/ATE59653T1/de not_active IP Right Cessation
- 1987-05-20 ES ES198787107345T patent/ES2031850T3/es not_active Expired - Lifetime
-
1991
- 1991-02-21 GR GR91400207T patent/GR3001494T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4792548A (en) | 1988-12-20 |
| GR3001494T3 (en) | 1992-10-08 |
| CA1283104C (en) | 1991-04-16 |
| EP0246633B1 (de) | 1991-01-02 |
| JPS62283978A (ja) | 1987-12-09 |
| ES2031850T3 (es) | 1993-01-01 |
| EP0246633A1 (de) | 1987-11-25 |
| DE3766884D1 (de) | 1991-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |