ATE555122T1 - Adp-ribosylierende bakterielle toxine - Google Patents

Adp-ribosylierende bakterielle toxine

Info

Publication number
ATE555122T1
ATE555122T1 AT02726389T AT02726389T ATE555122T1 AT E555122 T1 ATE555122 T1 AT E555122T1 AT 02726389 T AT02726389 T AT 02726389T AT 02726389 T AT02726389 T AT 02726389T AT E555122 T1 ATE555122 T1 AT E555122T1
Authority
AT
Austria
Prior art keywords
toxins
adp
bacterial toxins
ribosylating
ribosylating bacterial
Prior art date
Application number
AT02726389T
Other languages
English (en)
Inventor
Vega Masignani
Mariagrazia Pizza
Rino Rappuoli
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE555122T1 publication Critical patent/ATE555122T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/255Salmonella (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02726389T 2001-03-30 2002-03-28 Adp-ribosylierende bakterielle toxine ATE555122T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0108024.1A GB0108024D0 (en) 2001-03-30 2001-03-30 Bacterial toxins
PCT/IB2002/002080 WO2002079242A2 (en) 2001-03-30 2002-03-28 Adp-ribosylating bacterial toxins

Publications (1)

Publication Number Publication Date
ATE555122T1 true ATE555122T1 (de) 2012-05-15

Family

ID=9911929

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02726389T ATE555122T1 (de) 2001-03-30 2002-03-28 Adp-ribosylierende bakterielle toxine

Country Status (11)

Country Link
US (1) US7928192B2 (de)
EP (1) EP1379551B1 (de)
AT (1) ATE555122T1 (de)
AU (1) AU2002256859A1 (de)
CA (1) CA2442123A1 (de)
CY (1) CY1112918T1 (de)
DK (1) DK1379551T3 (de)
ES (1) ES2383592T3 (de)
GB (1) GB0108024D0 (de)
PT (1) PT1379551E (de)
WO (1) WO2002079242A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513371D0 (en) * 1995-06-30 1995-09-06 Biocine Spa Immunogenic detoxified mutant toxins
GB9326174D0 (en) * 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
GB0108024D0 (en) 2001-03-30 2001-05-23 Chiron Spa Bacterial toxins
DE60234695D1 (de) * 2001-06-07 2010-01-21 Univ Colorado Mutantenformen von cholera holotoxin als adjuvans
JP2005508143A (ja) 2001-06-07 2005-03-31 ワイス・ホールデイングス・コーポレーシヨン アジュバントとしてのコレラホロトキシンの突然変異形
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
PT1524993E (pt) * 2002-08-02 2013-06-12 Glaxosmithkline Biolog Sa Composições de vacina de neisseria compreendendo uma combinação de antigénios
GB0220205D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Neisseria toxin
EP2353608B1 (de) * 2002-10-11 2019-12-18 Novartis Vaccines and Diagnostics S.r.l. Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien
WO2005032491A2 (en) * 2003-10-03 2005-04-14 Board Of Regents, University Of Texas System Methods and compositions for mycoplasma pneumoniae exotoxins
US8586046B2 (en) 2003-10-03 2013-11-19 Board Of Regents, The University Of Texas System Methods and compositions for mycoplasma pneumoniae exotoxins
US20090104185A1 (en) * 2005-04-07 2009-04-23 Joel Barry Baseman Methods and Compositions for Mycoplasma Toxins
WO2006110132A1 (en) * 2005-04-07 2006-10-19 Board Of Regents, University Of Texas System Methods and compositions for mycoplasma pneumoniae exotoxins
US10335477B2 (en) * 2013-05-20 2019-07-02 Yale University Compositions and methods for diagnosing, preventing and treating Salmonella typhi and Salmonella paratyphi infection
US10646561B2 (en) 2015-07-23 2020-05-12 Yale University Compositions and methods for using Salmonella typhi toxin to induce or enhance an immune response

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9326174D0 (en) 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
AU1202200A (en) * 1998-10-09 2000-05-01 Chiron Corporation Neisseria genomic sequences and methods of their use
US7115730B1 (en) * 1999-04-27 2006-10-03 Chiron Srl Immunogenic detoxified mutant E. coli LT-A-toxin
EP1605061A1 (de) * 1999-04-30 2005-12-14 Chiron Corporation Genomische Sequenzen von Neisseria und Verfahren zu ihrer Verwendung
ES2563677T3 (es) 1999-05-19 2016-03-15 Glaxosmithkline Biologicals Sa Composiciones de combinaciones de Neisseria
GB0108024D0 (en) 2001-03-30 2001-05-23 Chiron Spa Bacterial toxins
GB0220205D0 (en) 2002-08-30 2002-10-09 Chiron Spa Neisseria toxin

Also Published As

Publication number Publication date
US7928192B2 (en) 2011-04-19
CY1112918T1 (el) 2016-04-13
AU2002256859A1 (en) 2002-10-15
EP1379551A2 (de) 2004-01-14
DK1379551T3 (da) 2012-07-30
US20060057155A1 (en) 2006-03-16
PT1379551E (pt) 2012-06-06
ES2383592T3 (es) 2012-06-22
CA2442123A1 (en) 2002-10-10
GB0108024D0 (en) 2001-05-23
WO2002079242A3 (en) 2003-11-06
EP1379551B1 (de) 2012-04-25
WO2002079242A2 (en) 2002-10-10

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