ATE545440T1 - Hybride biologische künstliche niere - Google Patents

Hybride biologische künstliche niere

Info

Publication number
ATE545440T1
ATE545440T1 AT08016833T AT08016833T ATE545440T1 AT E545440 T1 ATE545440 T1 AT E545440T1 AT 08016833 T AT08016833 T AT 08016833T AT 08016833 T AT08016833 T AT 08016833T AT E545440 T1 ATE545440 T1 AT E545440T1
Authority
AT
Austria
Prior art keywords
artificial kidney
biological artificial
hybrid biological
hollow fiber
cells
Prior art date
Application number
AT08016833T
Other languages
English (en)
Inventor
Reinhold Deppisch
David Luttropp
Bernd Krause
Markus Neubauer
Andrea Schnell
Original Assignee
Gambro Lundia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Lundia Ab filed Critical Gambro Lundia Ab
Application granted granted Critical
Publication of ATE545440T1 publication Critical patent/ATE545440T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A61M1/3489—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents by biological cells, e.g. bioreactor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • A61M1/3689—Chemical treatment by biological cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • B01D69/142—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers"
    • B01D69/144—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers" containing embedded or bound biomolecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14—Calcium; Ca chelators; Calcitonin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Microbiology (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT08016833T 2008-09-25 2008-09-25 Hybride biologische künstliche niere ATE545440T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08016833A EP2168614B1 (de) 2008-09-25 2008-09-25 Hybride biologische künstliche Niere

Publications (1)

Publication Number Publication Date
ATE545440T1 true ATE545440T1 (de) 2012-03-15

Family

ID=40347032

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08016833T ATE545440T1 (de) 2008-09-25 2008-09-25 Hybride biologische künstliche niere

Country Status (6)

Country Link
US (1) US8696909B2 (de)
EP (2) EP2168614B1 (de)
AT (1) ATE545440T1 (de)
AU (1) AU2009296331B2 (de)
CA (1) CA2736534C (de)
WO (1) WO2010034475A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE545440T1 (de) 2008-09-25 2012-03-15 Gambro Lundia Ab Hybride biologische künstliche niere
EP2168666A1 (de) 2008-09-25 2010-03-31 Gambro Lundia AB Bestrahlte Membran für Zellexpansion
EP2168668A1 (de) 2008-09-25 2010-03-31 Gambro Lundia AB Membran für Zellexpansion
EP2177603A1 (de) 2008-09-25 2010-04-21 Gambro Lundia AB Vorrichtung für Nierenzellexpansion
EP2488629B1 (de) * 2009-10-12 2020-03-11 Terumo BCT, Inc. Verfahren zur montage eines hohlfaserbioreaktors
SG190002A1 (en) * 2010-10-25 2013-06-28 Agency Science Tech & Res Tubular fiber membrane with nanoporous skin
SG11201406620QA (en) 2012-04-20 2014-11-27 Agency Science Tech & Res Bioreactor unit for use in bioartificial kidney device
JP6926331B2 (ja) 2017-10-05 2021-08-25 フレセニウス メディカル ケア ホールディングス インコーポレーテッド ポリスルホン−ウレタンコポリマー、それを含む膜および製品、並びに、その製造および使用方法
DE102019007144A1 (de) * 2019-10-15 2021-04-15 ProMedTec Germany GmbH Verfahren und Anordnung zur Verbesserung des Austausches von Gasen über semipermeable Membranen im wässrigen Milieu
CN111249552B (zh) * 2020-03-16 2020-11-17 南京鼓楼医院 基于人iPSCs诱导类肝细胞及多层多孔生物反应器的生物人工肝
EP4324495A4 (de) * 2021-04-15 2024-10-09 Toray Industries, Inc. Blutbehandlungsmaterial

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WO1989001967A1 (en) * 1987-09-03 1989-03-09 Brown University Research Foundation Blood purification with cultured renal cells
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ATE545440T1 (de) 2008-09-25 2012-03-15 Gambro Lundia Ab Hybride biologische künstliche niere
EP2168668A1 (de) * 2008-09-25 2010-03-31 Gambro Lundia AB Membran für Zellexpansion
EP2177603A1 (de) 2008-09-25 2010-04-21 Gambro Lundia AB Vorrichtung für Nierenzellexpansion
EP2168666A1 (de) * 2008-09-25 2010-03-31 Gambro Lundia AB Bestrahlte Membran für Zellexpansion

Also Published As

Publication number Publication date
EP2314672B1 (de) 2015-04-15
US20120067815A1 (en) 2012-03-22
CA2736534A1 (en) 2010-04-01
US8696909B2 (en) 2014-04-15
EP2168614B1 (de) 2012-02-15
EP2168614A1 (de) 2010-03-31
AU2009296331B2 (en) 2013-11-07
EP2314672A2 (de) 2011-04-27
EP2314672A3 (de) 2011-05-25
AU2009296331A1 (en) 2010-04-01
CA2736534C (en) 2016-10-25
WO2010034475A1 (en) 2010-04-01

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