ATE535609T1 - Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon - Google Patents

Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon

Info

Publication number
ATE535609T1
ATE535609T1 AT06750625T AT06750625T ATE535609T1 AT E535609 T1 ATE535609 T1 AT E535609T1 AT 06750625 T AT06750625 T AT 06750625T AT 06750625 T AT06750625 T AT 06750625T AT E535609 T1 ATE535609 T1 AT E535609T1
Authority
AT
Austria
Prior art keywords
protected
amino
substituted butane
epoxy
present
Prior art date
Application number
AT06750625T
Other languages
English (en)
Inventor
Nigel Bowers
Paul Skonezny
Gregory Stein
Thomas Franceschini
Shu-Jen Chiang
Wendy Anderson
Li You
Zizhuo Xing
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE535609T1 publication Critical patent/ATE535609T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06750625T 2005-05-25 2006-04-19 Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon ATE535609T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68430005P 2005-05-25 2005-05-25
US11/365,275 US7582468B2 (en) 2005-05-25 2006-03-01 Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof
PCT/US2006/014629 WO2006127180A1 (en) 2005-05-25 2006-04-19 A process for preparing (2r,3s)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof

Publications (1)

Publication Number Publication Date
ATE535609T1 true ATE535609T1 (de) 2011-12-15

Family

ID=36830991

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06750625T ATE535609T1 (de) 2005-05-25 2006-04-19 Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon

Country Status (6)

Country Link
US (2) US7582468B2 (de)
EP (1) EP1893765B1 (de)
AT (1) ATE535609T1 (de)
ES (1) ES2376345T3 (de)
TW (1) TW200716757A (de)
WO (1) WO2006127180A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0619240D0 (en) * 2006-09-29 2006-11-08 Almac Sciences Ltd Reduction of alpha-halo ketones
CN101778625A (zh) * 2007-06-22 2010-07-14 百时美施贵宝公司 含有阿扎那韦的压片组合物
MX2009013462A (es) * 2007-06-22 2010-01-15 Bristol Myers Squibb Co Composiciones comprimidas que contienen atazanavir.
JP2010530892A (ja) * 2007-06-22 2010-09-16 ブリストル−マイヤーズ スクイブ カンパニー アタザナビルを含む錠剤組成物
ES2449074T3 (es) * 2007-06-22 2014-03-18 Bristol-Myers Squibb Holdings Ireland Composiciones en forma de comprimidos que contienen atazanavir
SG177331A1 (en) 2009-06-22 2012-02-28 Codexis Inc Ketoreductase-mediated stereoselective route to alpha chloroalcohols
WO2011100265A2 (en) 2010-02-10 2011-08-18 Codexis, Inc. Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
EP2970927A4 (de) 2013-03-15 2016-10-12 Merck Sharp & Dohme Immobilisierte ketoreduktasen und verfahren zur herstellung und verwendung immobilisierter ketoreduktasen
CN108558793A (zh) * 2018-06-01 2018-09-21 徐州诺克非医药科技有限公司 一种中间体环氧化氨基苯丁烷的合成方法
CN112892190B (zh) * 2021-01-27 2023-03-10 成都中科绿生环境科技有限公司 一种化学除臭剂及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103932A1 (en) 1992-11-05 1994-05-06 Ramesh N. Patel Stereoselective reduction of ketones
JP3529904B2 (ja) 1995-06-19 2004-05-24 鐘淵化学工業株式会社 光学活性１−ハロ−３−アミノ−４−フェニル−２−ブタノール誘導体の製造法
US5849911A (en) 1996-04-22 1998-12-15 Novartis Finance Corporation Antivirally active heterocyclic azahexane derivatives
WO2000043357A1 (fr) 1999-01-21 2000-07-27 Kaneka Corporation Procede de purification et d'isolement de derives de (2s, 3s)- ou (2r, 3s)-halohydrine
WO2000044736A1 (fr) 1999-01-29 2000-08-03 Kaneka Corporation PROCEDE DE PREPARATION DE DERIVES DE threo-1,2-EPOXY-3-AMINO-4-PHENYLBUTANE
US6605732B1 (en) 1999-05-03 2003-08-12 Aerojet Fine Chemicals Llc Clean, high-yield preparation of S,S and R,S amino acid isosteres
KR100708221B1 (ko) 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법
US20020042124A1 (en) * 2000-08-16 2002-04-11 Patel Ramesh N. Stereoselective reduction of substituted oxo-butanes
US6764545B2 (en) * 2000-12-12 2004-07-20 Ajinomoto Co., Inc. Production method of epoxide crystal

Also Published As

Publication number Publication date
EP1893765A1 (de) 2008-03-05
TW200716757A (en) 2007-05-01
US7582468B2 (en) 2009-09-01
US20060270012A1 (en) 2006-11-30
ES2376345T3 (es) 2012-03-13
WO2006127180A1 (en) 2006-11-30
EP1893765B1 (de) 2011-11-30
US20090286303A1 (en) 2009-11-19
US8119389B2 (en) 2012-02-21

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