ATE528315T1 - Cardioprotektive verbindungen - Google Patents
Cardioprotektive verbindungenInfo
- Publication number
- ATE528315T1 ATE528315T1 AT07794118T AT07794118T ATE528315T1 AT E528315 T1 ATE528315 T1 AT E528315T1 AT 07794118 T AT07794118 T AT 07794118T AT 07794118 T AT07794118 T AT 07794118T AT E528315 T1 ATE528315 T1 AT E528315T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- substituted
- optionally
- acid residue
- amino acid
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000003293 cardioprotective effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- -1 nitro, fluoro, chloro, bromo, iodo Chemical group 0.000 abstract 1
- 230000002669 organ and tissue protective effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Ceramic Products (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0601695 | 2006-08-17 | ||
| PCT/SE2007/000731 WO2008020802A1 (en) | 2006-08-17 | 2007-08-17 | Cardioprotective compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE528315T1 true ATE528315T1 (de) | 2011-10-15 |
Family
ID=38645719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07794118T ATE528315T1 (de) | 2006-08-17 | 2007-08-17 | Cardioprotektive verbindungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100093643A1 (de) |
| EP (1) | EP2051991B1 (de) |
| JP (1) | JP2010500991A (de) |
| CN (1) | CN101506225A (de) |
| AT (1) | ATE528315T1 (de) |
| AU (1) | AU2007285045A1 (de) |
| CA (1) | CA2661014A1 (de) |
| DK (1) | DK2051991T3 (de) |
| WO (1) | WO2008020802A1 (de) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55141453A (en) * | 1979-04-23 | 1980-11-05 | Takeda Chem Ind Ltd | Tetrapeptide derivative |
| GB8314646D0 (en) * | 1983-05-26 | 1983-06-29 | Wellcome Found | Pharmaceutical amides |
| CA2361534C (en) * | 1999-01-29 | 2011-08-30 | University Of Utah Research Foundation | Alpha-conotoxin peptides |
| US6797808B1 (en) * | 1999-01-29 | 2004-09-28 | University Of Utah Research Foundation | α-conotoxin peptides |
| WO2000076532A1 (en) * | 1999-06-10 | 2000-12-21 | University Of Utah Research Foundation | νO-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS |
| US20020198145A1 (en) * | 1999-06-10 | 2002-12-26 | Cognetix, Inc. | MuO-conopeptides and their use as local anesthetics |
| WO2002007756A1 (en) * | 2000-07-20 | 2002-01-31 | Cognetix, Inc. | MuO-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS |
-
2007
- 2007-08-17 CN CNA2007800306049A patent/CN101506225A/zh active Pending
- 2007-08-17 US US12/310,193 patent/US20100093643A1/en not_active Abandoned
- 2007-08-17 WO PCT/SE2007/000731 patent/WO2008020802A1/en not_active Ceased
- 2007-08-17 DK DK07794118.5T patent/DK2051991T3/da active
- 2007-08-17 JP JP2009524581A patent/JP2010500991A/ja active Pending
- 2007-08-17 EP EP07794118A patent/EP2051991B1/de active Active
- 2007-08-17 AU AU2007285045A patent/AU2007285045A1/en not_active Abandoned
- 2007-08-17 CA CA002661014A patent/CA2661014A1/en not_active Abandoned
- 2007-08-17 AT AT07794118T patent/ATE528315T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20100093643A1 (en) | 2010-04-15 |
| EP2051991B1 (de) | 2011-10-12 |
| WO2008020802A1 (en) | 2008-02-21 |
| JP2010500991A (ja) | 2010-01-14 |
| EP2051991A1 (de) | 2009-04-29 |
| CN101506225A (zh) | 2009-08-12 |
| AU2007285045A1 (en) | 2008-02-21 |
| DK2051991T3 (da) | 2012-01-30 |
| CA2661014A1 (en) | 2008-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |