ATE52806T1 - Verfahren zur mikrobiologischen herstellung von menschlichem serum-albumin. - Google Patents
Verfahren zur mikrobiologischen herstellung von menschlichem serum-albumin.Info
- Publication number
- ATE52806T1 ATE52806T1 AT86400617T AT86400617T ATE52806T1 AT E52806 T1 ATE52806 T1 AT E52806T1 AT 86400617 T AT86400617 T AT 86400617T AT 86400617 T AT86400617 T AT 86400617T AT E52806 T1 ATE52806 T1 AT E52806T1
- Authority
- AT
- Austria
- Prior art keywords
- serum albumin
- human serum
- microbiological preparation
- gene
- renatured
- Prior art date
Links
- 108091006905 Human Serum Albumin Proteins 0.000 title abstract 3
- 102000008100 Human Serum Albumin Human genes 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000002906 microbiologic effect Effects 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 241000701959 Escherichia virus Lambda Species 0.000 abstract 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
- 108091081024 Start codon Proteins 0.000 abstract 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
- 101150057411 cII gene Proteins 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000005030 transcription termination Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8504384A FR2579223B1 (fr) | 1985-03-25 | 1985-03-25 | Procede de preparation microbiologique de la serum-albumine humaine |
| EP86400617A EP0198745B1 (de) | 1985-03-25 | 1986-03-24 | Verfahren zur mikrobiologischen Herstellung von menschlichem Serum-Albumin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE52806T1 true ATE52806T1 (de) | 1990-06-15 |
Family
ID=9317531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86400617T ATE52806T1 (de) | 1985-03-25 | 1986-03-24 | Verfahren zur mikrobiologischen herstellung von menschlichem serum-albumin. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5037744A (de) |
| EP (1) | EP0198745B1 (de) |
| JP (1) | JPS61275229A (de) |
| AT (1) | ATE52806T1 (de) |
| CA (1) | CA1262695A (de) |
| DE (1) | DE3671243D1 (de) |
| FR (1) | FR2579223B1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2610324A1 (fr) * | 1987-01-29 | 1988-08-05 | Genetica Sa | Preparation par voie microbiologique de l'angiogenine humaine et conversion de l'enzyme ainsi obtenue en sa forme active |
| JPH01215289A (ja) * | 1988-02-22 | 1989-08-29 | Toa Nenryo Kogyo Kk | 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法 |
| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| US5260202A (en) * | 1988-09-07 | 1993-11-09 | Delta Biotechnology Limited | Fermentation method |
| FR2680518A1 (fr) * | 1991-08-21 | 1993-02-26 | Rhone Poulenc Rorer Sa | Promoteur de levure et son utilisation. |
| US6551618B2 (en) | 1994-03-15 | 2003-04-22 | University Of Birmingham | Compositions and methods for delivery of agents for neuronal regeneration and survival |
| US6274305B1 (en) | 1996-12-19 | 2001-08-14 | Tufts University | Inhibiting proliferation of cancer cells |
| US6232443B1 (en) * | 1997-04-08 | 2001-05-15 | University Of Pittsburgh | Renal nuclear matrix proteins, polynucleotide sequences encoding them, and their use |
| US11739166B2 (en) | 2020-07-02 | 2023-08-29 | Davol Inc. | Reactive polysaccharide-based hemostatic agent |
| CN112898407B (zh) * | 2021-01-25 | 2022-07-12 | 南京医科大学 | 重组驼源血清白蛋白的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4551433A (en) * | 1981-05-18 | 1985-11-05 | Genentech, Inc. | Microbial hybrid promoters |
| IL66614A (en) * | 1981-08-28 | 1985-09-29 | Genentech Inc | Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it |
| EP0079739A3 (de) * | 1981-11-12 | 1984-08-08 | The Upjohn Company | Auf Albumin basierende Nukleotiden, ihre Replikation und Verwendung und Plasmide zur Verwendung darin |
| EP0091527A3 (de) * | 1981-12-14 | 1984-07-25 | The President And Fellows Of Harvard College | DNS Sequenzen, rekombinante DNS Moleküle und Verfahren zur Herstellung von menschlichem Serum Albumin ähnlichen Polypeptiden |
| GR79124B (de) * | 1982-12-22 | 1984-10-02 | Genentech Inc | |
| US4511502A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4578355A (en) * | 1983-01-12 | 1986-03-25 | The United States Of America As Represented By The Department Of Health And Human Services | Plasmid cloning vector pAS1 |
| BG49718A3 (en) * | 1983-07-15 | 1992-01-15 | Bio Technology General Corp | Method for preparing of polypeptid with superoxiddismutasne activitty |
| JPS6087792A (ja) * | 1983-09-23 | 1985-05-17 | ジェネックス・コーポレイション | 雑種制御領域 |
| US4792523A (en) * | 1984-08-31 | 1988-12-20 | Cetus Corporation | 3'Expression enhancing fragments and method |
| FR2579224B1 (fr) * | 1985-03-25 | 1987-05-22 | Genetica | Procede de preparation microbiologique de la serum-albumine humaine |
-
1985
- 1985-03-25 FR FR8504384A patent/FR2579223B1/fr not_active Expired
-
1986
- 1986-03-24 DE DE8686400617T patent/DE3671243D1/de not_active Expired - Fee Related
- 1986-03-24 EP EP86400617A patent/EP0198745B1/de not_active Expired - Lifetime
- 1986-03-24 AT AT86400617T patent/ATE52806T1/de not_active IP Right Cessation
- 1986-03-25 CA CA000504966A patent/CA1262695A/fr not_active Expired
- 1986-03-25 JP JP61067041A patent/JPS61275229A/ja active Pending
-
1989
- 1989-12-13 US US07/449,351 patent/US5037744A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2579223B1 (fr) | 1988-12-09 |
| CA1262695A (fr) | 1989-11-07 |
| FR2579223A1 (fr) | 1986-09-26 |
| DE3671243D1 (de) | 1990-06-21 |
| EP0198745B1 (de) | 1990-05-16 |
| JPS61275229A (ja) | 1986-12-05 |
| EP0198745A1 (de) | 1986-10-22 |
| US5037744A (en) | 1991-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |