ATE508167T1 - Membranaktive polymere - Google Patents
Membranaktive polymereInfo
- Publication number
- ATE508167T1 ATE508167T1 AT04707130T AT04707130T ATE508167T1 AT E508167 T1 ATE508167 T1 AT E508167T1 AT 04707130 T AT04707130 T AT 04707130T AT 04707130 T AT04707130 T AT 04707130T AT E508167 T1 ATE508167 T1 AT E508167T1
- Authority
- AT
- Austria
- Prior art keywords
- membrane
- active polymers
- polymers
- delivery
- compounds
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000001086 cytosolic effect Effects 0.000 abstract 1
- 229920000141 poly(maleic anhydride) Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Measurement Of Length, Angles, Or The Like Using Electric Or Magnetic Means (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44390603P | 2003-01-31 | 2003-01-31 | |
| US10/765,668 US7871818B2 (en) | 2003-01-31 | 2004-01-27 | Membrane active polymers |
| PCT/US2004/003573 WO2004070019A2 (en) | 2003-01-31 | 2004-01-30 | Membrane active polymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE508167T1 true ATE508167T1 (de) | 2011-05-15 |
Family
ID=32776200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04707130T ATE508167T1 (de) | 2003-01-31 | 2004-01-30 | Membranaktive polymere |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7871818B2 (de) |
| EP (1) | EP1587869B1 (de) |
| AT (1) | ATE508167T1 (de) |
| DE (1) | DE602004032515D1 (de) |
| WO (1) | WO2004070019A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1981543A1 (de) * | 2006-01-23 | 2008-10-22 | Abbott Laboratories | Chemisch modifiziertes polykationpolymer für sirna-abgabe |
| US20100035248A1 (en) * | 2007-06-15 | 2010-02-11 | Rastislav Levicky | Surface-based nucleic acid assays employing morpholinos |
| CN103342789B (zh) * | 2008-05-13 | 2016-11-23 | 华盛顿大学 | 用于向细胞内递送的二嵌段共聚物和其多核苷酸复合物 |
| WO2009140423A2 (en) * | 2008-05-13 | 2009-11-19 | University Of Washington | Targeted polymer bioconjugates |
| WO2009140421A2 (en) * | 2008-05-13 | 2009-11-19 | University Of Washington | Polymeric carrier |
| KR20110020804A (ko) * | 2008-05-13 | 2011-03-03 | 유니버시티 오브 워싱톤 | 치료제의 세포내 전달을 위한 미셀 |
| CN102066444A (zh) | 2008-05-13 | 2011-05-18 | 华盛顿大学 | 胶束装配体 |
| WO2010021770A1 (en) | 2008-08-22 | 2010-02-25 | University Of Washington | Heterogeneous polymeric micelles for intracellular delivery |
| MX2011004242A (es) | 2008-11-06 | 2011-07-20 | Univ Washington | Copolimeros multibloque. |
| US8822213B2 (en) | 2008-11-06 | 2014-09-02 | University Of Washington | Bispecific intracellular delivery vehicles |
| WO2010077678A2 (en) | 2008-12-08 | 2010-07-08 | University Of Washington | Omega-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization |
| WO2011062965A2 (en) | 2009-11-18 | 2011-05-26 | University Of Washington Through Its Center For Commercialization | Targeting monomers and polymers having targeting blocks |
| AU2014296278C1 (en) | 2013-07-30 | 2023-02-02 | Genevant Sciences Gmbh | Block copolymers and their conjugates or complexes with oligonucleotides |
| WO2016118697A1 (en) | 2015-01-21 | 2016-07-28 | Phaserx, Inc. | Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells |
| US11684584B2 (en) | 2016-12-30 | 2023-06-27 | Genevant Sciences Gmbh | Branched peg molecules and related compositions and methods |
| GB201804233D0 (en) | 2018-03-16 | 2018-05-02 | Univ Warwick | Cryopreserving processes |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1241294A (en) * | 1967-10-23 | 1971-08-04 | Ici Ltd | A PROCESS FOR THE PREPARATION OF AMIDE-ACID DERIVATIVES OF alpha,beta-UNSATURATED DICARBOXYLIC AND ANHYDRIDE COPOLYMERS |
| EP0087957B1 (de) * | 1982-02-27 | 1986-11-26 | Kuraray Co., Ltd. | Neocarzinostatinkomplexe, Verfahren zu ihrer Herstellung und Antitumormittel, das diese Komplexe als aktive Komponente enhält |
| US5118551A (en) * | 1990-03-27 | 1992-06-02 | Allied-Signal Inc. | Method to impart stain resistance to polyamide textile substrates |
| AUPO379596A0 (en) * | 1996-11-22 | 1996-12-19 | Soltec Research Pty Ltd | Percutaneous delivery system |
| GB9717905D0 (en) * | 1997-08-22 | 1997-10-29 | Univ Aston | Lipid-containing compositions and uses thereof |
| CA2317549C (en) * | 1998-01-05 | 2006-04-11 | University Of Washington | Composition for enhancing transport through lipid-containing membranes, and uses thereof |
| US20050153926A1 (en) * | 1998-12-04 | 2005-07-14 | Adams Christopher P. | Method for the immobilization of oligonucleotides |
| US20020052335A1 (en) * | 1999-11-29 | 2002-05-02 | Rozema David B. | Charge reversal of polyion complexes |
| WO2001049841A1 (en) * | 1999-12-31 | 2001-07-12 | Mirus Corporation | Polyampholytes for delivering polyions to a cell |
| US6740336B2 (en) * | 2002-10-04 | 2004-05-25 | Mirus Corporation | Process for generating multilayered particles |
-
2004
- 2004-01-27 US US10/765,668 patent/US7871818B2/en not_active Expired - Fee Related
- 2004-01-30 DE DE602004032515T patent/DE602004032515D1/de not_active Expired - Lifetime
- 2004-01-30 EP EP04707130A patent/EP1587869B1/de not_active Expired - Lifetime
- 2004-01-30 WO PCT/US2004/003573 patent/WO2004070019A2/en not_active Ceased
- 2004-01-30 AT AT04707130T patent/ATE508167T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004070019A3 (en) | 2005-04-14 |
| DE602004032515D1 (de) | 2011-06-16 |
| WO2004070019A2 (en) | 2004-08-19 |
| US7871818B2 (en) | 2011-01-18 |
| EP1587869B1 (de) | 2011-05-04 |
| EP1587869A4 (de) | 2006-02-22 |
| US20040151775A1 (en) | 2004-08-05 |
| EP1587869A2 (de) | 2005-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |