ATE490976T1 - B-lactam-rgd-cyclopeptide mit gamma-(g-)wendungen - Google Patents

B-lactam-rgd-cyclopeptide mit gamma-(g-)wendungen

Info

Publication number
ATE490976T1
ATE490976T1 AT04791400T AT04791400T ATE490976T1 AT E490976 T1 ATE490976 T1 AT E490976T1 AT 04791400 T AT04791400 T AT 04791400T AT 04791400 T AT04791400 T AT 04791400T AT E490976 T1 ATE490976 T1 AT E490976T1
Authority
AT
Austria
Prior art keywords
unsubstituted
substituted
lactam
beta
useful
Prior art date
Application number
AT04791400T
Other languages
English (en)
Inventor
Iparraguirre Jesus Ma Aizpurua
Landa Jose Ignacio Gamboa
Nicolao Claudio Palomo
Bordonabe Iradia Loinaz
Murua Jose Ignacio Miranda
Original Assignee
Univ Pais Vasco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pais Vasco filed Critical Univ Pais Vasco
Application granted granted Critical
Publication of ATE490976T1 publication Critical patent/ATE490976T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT04791400T 2004-10-30 2004-10-30 B-lactam-rgd-cyclopeptide mit gamma-(g-)wendungen ATE490976T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ES2004/000481 WO2006048473A1 (es) 2004-10-30 2004-10-30 CICLOPÉPTIDOS RGD β-LACTÁMINOS GIROS GAMMA (Ϝ)

Publications (1)

Publication Number Publication Date
ATE490976T1 true ATE490976T1 (de) 2010-12-15

Family

ID=36318908

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04791400T ATE490976T1 (de) 2004-10-30 2004-10-30 B-lactam-rgd-cyclopeptide mit gamma-(g-)wendungen

Country Status (5)

Country Link
EP (1) EP1864995B1 (de)
AT (1) ATE490976T1 (de)
DE (1) DE602004030494D1 (de)
ES (1) ES2357800T3 (de)
WO (1) WO2006048473A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101990425B (zh) * 2008-04-08 2016-01-20 默克专利股份有限公司 包含环肽的组合物和使用方法
EP2407478A1 (de) 2010-07-14 2012-01-18 GENETADI Biotech, S.L. Neue Cyclotetrapeptide mit pro-angiogenen Eigenschaften
US9345691B2 (en) 2011-09-21 2016-05-24 Stem Cell Medicine Ltd. Beta-lactam compounds for enhancing T cell-mediated immune responses
US9474744B2 (en) 2011-09-21 2016-10-25 Stem Cell Medicine Ltd. Beta-lactam compounds for treating diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4415310A1 (de) * 1994-04-30 1995-11-02 Merck Patent Gmbh Cyclopeptide
US6235877B1 (en) * 1999-08-04 2001-05-22 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Peptido-mimetic compounds containing RGD sequence useful as integrin inhibitors
ITRM20020370A1 (it) * 2002-07-09 2004-01-09 Sigma Tau Ind Farmaceuti Composto peptido-mimetico contenente la sequenza rgd utile come inibitore delle integrine.

Also Published As

Publication number Publication date
EP1864995B1 (de) 2010-12-08
WO2006048473A1 (es) 2006-05-11
ES2357800T3 (es) 2011-04-29
DE602004030494D1 (de) 2011-01-20
EP1864995A1 (de) 2007-12-12

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties