ATE490237T1 - Anionisch substituierte 7-nitroindol derivate und deren verwendung - Google Patents

Anionisch substituierte 7-nitroindol derivate und deren verwendung

Info

Publication number
ATE490237T1
ATE490237T1 AT06254350T AT06254350T ATE490237T1 AT E490237 T1 ATE490237 T1 AT E490237T1 AT 06254350 T AT06254350 T AT 06254350T AT 06254350 T AT06254350 T AT 06254350T AT E490237 T1 ATE490237 T1 AT E490237T1
Authority
AT
Austria
Prior art keywords
anionic substituted
derivatives
nitroindole
nitroindole derivatives
substituted
Prior art date
Application number
AT06254350T
Other languages
English (en)
Inventor
John Edgar Thomas Corrie
David Ogden
George Papageorgiou
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of ATE490237T1 publication Critical patent/ATE490237T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT06254350T 2005-08-26 2006-08-18 Anionisch substituierte 7-nitroindol derivate und deren verwendung ATE490237T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71159705P 2005-08-26 2005-08-26

Publications (1)

Publication Number Publication Date
ATE490237T1 true ATE490237T1 (de) 2010-12-15

Family

ID=37603322

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06254350T ATE490237T1 (de) 2005-08-26 2006-08-18 Anionisch substituierte 7-nitroindol derivate und deren verwendung

Country Status (4)

Country Link
US (1) US7737169B2 (de)
EP (1) EP1757585B1 (de)
AT (1) ATE490237T1 (de)
DE (1) DE602006018565D1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394294B2 (en) * 2010-05-11 2016-07-19 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8765737B1 (en) * 2010-05-11 2014-07-01 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US9586954B2 (en) 2010-06-22 2017-03-07 Demerx, Inc. N-substituted noribogaine prodrugs
US8741891B1 (en) 2010-06-22 2014-06-03 Demerx, Inc. N-substituted noribogaine prodrugs
US9358237B2 (en) 2010-07-23 2016-06-07 Demerx, Inc. Noribogaine compositions
EP2481740B1 (de) 2011-01-26 2015-11-04 DemeRx, Inc. Verfahren und Zusammensetzungen zur Herstellung von Noribogain aus Voacangin
US9617274B1 (en) 2011-08-26 2017-04-11 Demerx, Inc. Synthetic noribogaine
WO2013050795A1 (en) 2011-10-03 2013-04-11 Femtonics Kft. Use of photoactive compounds
EP2788003A4 (de) 2011-12-09 2015-05-27 Demerx Inc Phosphatester von noribogain
CA2858820C (en) 2012-01-25 2021-08-17 Demerx, Inc. Synthetic voacangine
US9045481B2 (en) 2012-12-20 2015-06-02 Demerx, Inc. Substituted noribogaine
CA2896133A1 (en) 2012-12-20 2014-06-26 Demerx, Inc. Substituted noribogaine
US8940728B2 (en) 2012-12-20 2015-01-27 Demerx, Inc. Substituted noribogaine
CN103044311B (zh) * 2012-12-26 2015-04-22 山东大学 一种多取代吲哚类化合物及其制备方法和应用
US11370757B2 (en) * 2017-10-18 2022-06-28 Board Of Regents, The University Of Texas System Photocleavable nitroindoline-based crosslinkers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9906192D0 (en) * 1999-03-18 1999-05-12 Medical Res Council Photoreleasable compounds
GB0109093D0 (en) * 2001-04-11 2001-05-30 Medical Res Council Process for producing photocleavable compounds
GB0307231D0 (en) 2003-03-28 2003-04-30 Medical Res Council 7-Nitroindoline derivatives and their uses

Also Published As

Publication number Publication date
EP1757585A1 (de) 2007-02-28
DE602006018565D1 (de) 2011-01-13
US20070203099A1 (en) 2007-08-30
US7737169B2 (en) 2010-06-15
EP1757585B1 (de) 2010-12-01

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Legal Events

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