ATE485393T1 - METHOD FOR FINDING THE FUNCTION OF A GENE - Google Patents
METHOD FOR FINDING THE FUNCTION OF A GENEInfo
- Publication number
- ATE485393T1 ATE485393T1 AT04717084T AT04717084T ATE485393T1 AT E485393 T1 ATE485393 T1 AT E485393T1 AT 04717084 T AT04717084 T AT 04717084T AT 04717084 T AT04717084 T AT 04717084T AT E485393 T1 ATE485393 T1 AT E485393T1
- Authority
- AT
- Austria
- Prior art keywords
- amount
- gene
- organism
- metabolites
- transcript
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
Abstract
Described is a method for determining the function of a gene. This method involves determining the amount of transcript for each of a set of candidate genes in samples taken from different phenotypic and/or genotypic states of an organism and determining the amount of each of a plurality of metabolites in different samples taken from the same states as those mentioned above. Subsequently, the data obtained is analyzed by suitable mathematical methods in order to identify a transcript and metabolites which correlate in the different states, thereby identifying a transcript corresponding to a gene which influences the amount of metabolites in the organism. Furthermore described is a method for identifying a gene which is capable of modifying the amount of a metabolite in an organism and to a method for identifying a metabolite which is capable of modifying the amount of a transcript in an organism. Likewise, uses of the genes and metabolites identified in the aforementioned methods are described.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03004838A EP1454993A1 (en) | 2003-03-05 | 2003-03-05 | Method for identifying the function of a gene |
PCT/EP2004/002201 WO2004079006A1 (en) | 2003-03-05 | 2004-03-04 | Method for identifying the function of a gene |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE485393T1 true ATE485393T1 (en) | 2010-11-15 |
Family
ID=32798777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04717084T ATE485393T1 (en) | 2003-03-05 | 2004-03-04 | METHOD FOR FINDING THE FUNCTION OF A GENE |
Country Status (7)
Country | Link |
---|---|
US (1) | US20080288174A1 (en) |
EP (2) | EP1454993A1 (en) |
AT (1) | ATE485393T1 (en) |
AU (1) | AU2004217819B2 (en) |
CA (1) | CA2518045A1 (en) |
DE (1) | DE602004029654D1 (en) |
WO (1) | WO2004079006A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7868229B2 (en) | 1999-03-23 | 2011-01-11 | Mendel Biotechnology, Inc. | Early flowering in genetically modified plants |
US8633353B2 (en) | 1999-03-23 | 2014-01-21 | Mendel Biotechnology, Inc. | Plants with improved water deficit and cold tolerance |
CN107937414B (en) * | 2017-12-11 | 2019-03-29 | 西南大学 | Belladonna WRKY class transcription factor gene and its recombinant plant expression vector and application |
CN108802250B (en) * | 2018-08-28 | 2020-09-25 | 上海中医药大学 | Method for detecting 11 neurotransmitters in brain microdialysis solution by ultra-high performance liquid chromatography-mass spectrometry |
CN109187841B (en) * | 2018-08-31 | 2020-11-13 | 成都大学 | Thin-layer identification method of coptidis flos |
CN109486838B (en) * | 2018-12-21 | 2021-09-17 | 中国农业科学院北京畜牧兽医研究所 | Transcription factor gene for regulating plant flavonoid synthesis and application thereof |
CN109337884B9 (en) * | 2018-12-21 | 2021-10-29 | 中国农业科学院北京畜牧兽医研究所 | Pyruvate kinase gene and application thereof |
CN109633016A (en) * | 2018-12-29 | 2019-04-16 | 上海微谱化工技术服务有限公司 | The analysis method of key component in a kind of cosmetics quality control |
CN111690046B (en) * | 2020-07-03 | 2021-10-26 | 南京农业大学 | Pear transcription factor PbHB.G7.2 and application thereof in promoting fruit ripening |
CN112326826A (en) * | 2020-10-30 | 2021-02-05 | 南京农业大学 | Method for screening key metabolites responding to high-temperature stress of poplar |
CN114369602B (en) * | 2021-12-09 | 2023-02-03 | 西北农林科技大学 | VlbZIP30 gene for promoting synthesis of anthocyanin and application thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1327883A3 (en) * | 2002-01-10 | 2003-07-30 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Combined metabolomic, proteomic and transcriptomic analysis from one, single sample and suitable statistical evaluation of data |
-
2003
- 2003-03-05 EP EP03004838A patent/EP1454993A1/en not_active Withdrawn
-
2004
- 2004-03-04 CA CA002518045A patent/CA2518045A1/en not_active Abandoned
- 2004-03-04 EP EP04717084A patent/EP1601794B1/en not_active Expired - Lifetime
- 2004-03-04 WO PCT/EP2004/002201 patent/WO2004079006A1/en active Application Filing
- 2004-03-04 US US10/548,226 patent/US20080288174A1/en not_active Abandoned
- 2004-03-04 DE DE602004029654T patent/DE602004029654D1/en not_active Expired - Lifetime
- 2004-03-04 AU AU2004217819A patent/AU2004217819B2/en not_active Ceased
- 2004-03-04 AT AT04717084T patent/ATE485393T1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1601794B1 (en) | 2010-10-20 |
US20080288174A1 (en) | 2008-11-20 |
AU2004217819B2 (en) | 2009-10-22 |
WO2004079006A1 (en) | 2004-09-16 |
AU2004217819A1 (en) | 2004-09-16 |
EP1454993A1 (en) | 2004-09-08 |
EP1601794A1 (en) | 2005-12-07 |
DE602004029654D1 (en) | 2010-12-02 |
CA2518045A1 (en) | 2004-09-16 |
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