ATE481379T1 - N-alkylcarbonyl-d- aminohydroxyalkylesterverbindungen und ihre verwendung - Google Patents
N-alkylcarbonyl-d- aminohydroxyalkylesterverbindungen und ihre verwendungInfo
- Publication number
- ATE481379T1 ATE481379T1 AT07824449T AT07824449T ATE481379T1 AT E481379 T1 ATE481379 T1 AT E481379T1 AT 07824449 T AT07824449 T AT 07824449T AT 07824449 T AT07824449 T AT 07824449T AT E481379 T1 ATE481379 T1 AT E481379T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- cooling
- itch
- menthol
- perception
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 abstract 3
- 210000000214 mouth Anatomy 0.000 abstract 3
- 206010011224 Cough Diseases 0.000 abstract 2
- 208000003251 Pruritus Diseases 0.000 abstract 2
- 238000001816 cooling Methods 0.000 abstract 2
- 230000008447 perception Effects 0.000 abstract 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 1
- BWSXEMSUCIVMLV-APIJFGDWSA-N 3-hydroxypropyl (2r)-2-[[(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexanecarbonyl]amino]propanoate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1C(=O)N[C@H](C)C(=O)OCCCO BWSXEMSUCIVMLV-APIJFGDWSA-N 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 abstract 1
- 206010033372 Pain and discomfort Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000035597 cooling sensation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 229940041616 menthol Drugs 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- 210000004126 nerve fiber Anatomy 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 230000001953 sensory effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85789706P | 2006-11-08 | 2006-11-08 | |
| US92151307P | 2007-04-02 | 2007-04-02 | |
| PCT/GB2007/004213 WO2008056119A1 (en) | 2006-11-08 | 2007-11-05 | N-alkylcarbonyl-d-amino hydroxyalkyl ester compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE481379T1 true ATE481379T1 (de) | 2010-10-15 |
Family
ID=38871739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07824449T ATE481379T1 (de) | 2006-11-08 | 2007-11-05 | N-alkylcarbonyl-d- aminohydroxyalkylesterverbindungen und ihre verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110039812A1 (de) |
| EP (1) | EP2079681B1 (de) |
| JP (1) | JP2010509299A (de) |
| AT (1) | ATE481379T1 (de) |
| DE (1) | DE602007009283D1 (de) |
| ES (1) | ES2350618T3 (de) |
| WO (1) | WO2008056119A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010255540A1 (en) * | 2009-06-05 | 2012-01-19 | Edward Tak Wei | Treatment of eye discomfort by topical administration of a cooling agent to the external surface of the eyelid |
| CN104159580A (zh) * | 2011-12-21 | 2014-11-19 | Wm.雷格利Jr.公司 | 含有[(2-异丙基-5-甲基-环己烷羰基)-氨基]-乙酸异丙酯的口香糖产品 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1351761A (en) * | 1971-02-04 | 1974-05-01 | Wilkinson Sword Ltd | Substituted p-menthane carboxamides and compositions containing them |
| JPS61194049A (ja) * | 1985-02-22 | 1986-08-28 | Takasago Corp | ｌ−メンチル３−ヒドロキシブチレ−ト，その製造法およびこれを有効成分とする冷感剤 |
| US20070155755A1 (en) * | 2004-02-23 | 2007-07-05 | Wei Edward T | N-arylshydroxyalkylidene-carboxamide compositions and methods |
| WO2006103401A2 (en) * | 2005-03-29 | 2006-10-05 | Paget, Hugh, Charles, Edward | N-alkylcarbonyl-amino acid ester and n-alkylcarbonyl-amino lactone compounds and their use |
-
2007
- 2007-11-05 US US12/513,586 patent/US20110039812A1/en not_active Abandoned
- 2007-11-05 WO PCT/GB2007/004213 patent/WO2008056119A1/en not_active Ceased
- 2007-11-05 AT AT07824449T patent/ATE481379T1/de not_active IP Right Cessation
- 2007-11-05 EP EP07824449A patent/EP2079681B1/de active Active
- 2007-11-05 JP JP2009535786A patent/JP2010509299A/ja active Pending
- 2007-11-05 DE DE602007009283T patent/DE602007009283D1/de active Active
- 2007-11-05 ES ES07824449T patent/ES2350618T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2350618T3 (es) | 2011-01-25 |
| EP2079681B1 (de) | 2010-09-15 |
| DE602007009283D1 (de) | 2010-10-28 |
| US20110039812A1 (en) | 2011-02-17 |
| JP2010509299A (ja) | 2010-03-25 |
| EP2079681A1 (de) | 2009-07-22 |
| WO2008056119A1 (en) | 2008-05-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2006103401A3 (en) | N-alkylcarbonyl-amino acid ester and n-alkylcarbonyl-amino lactone compounds and their use | |
| EA201590933A1 (ru) | Новые перорально биодоступные соединения, модулирующие контроль дыхания, и способы их использования | |
| MX337548B (es) | Nuevos compuestos para tratamiento de enfermedades asociadas con proteinas amiloides o tipo amiloide. | |
| NO20076508L (no) | Acyloksykarbamat prodroger av traneksaminsyre og fremgangsmater for fremstilling og anvendelse derav | |
| PH12014500472A1 (en) | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof | |
| WO2008002621A3 (en) | Benzyl-substituted quinolone m1 receptor positive allosteric modulators | |
| TN2012000231A1 (en) | Quinoline amide m1 receptor positive allosteric modulators | |
| AU2012286851A8 (en) | Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof | |
| BR112014015482A2 (pt) | compostos carbamato de fenila para uso no alívio ou tratamento de dor e dor neuropática | |
| PH12017502049A1 (en) | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof | |
| MY159377A (en) | Aqueous suspensions of ciclesonide for nebulisation | |
| MX2022005414A (es) | Inhibidores de adrenoreceptor adrac2. | |
| SG178942A1 (en) | Method of treatment of neurodegenerative or neuro-muscular degenerative diseases and therapeutic agent to treat the same | |
| CA2864606C (en) | Methods of treating and preventing diseases and disorders of the central nervous system | |
| AU2001266289A1 (en) | 2-arachidonylglycerol (2-ag) - an inhibitor of tumor necrosis factor -alfa and neuroprotector of brain in closed head injury | |
| WO2009003694A3 (en) | Method for treating diseases related to mitochondrial dysfunction | |
| CA3014725C (en) | Compositions and methods for treating nasal and paranasal mucosa diseases with nicotinic acetylcholine receptor agonists | |
| ATE481379T1 (de) | N-alkylcarbonyl-d- aminohydroxyalkylesterverbindungen und ihre verwendung | |
| ATE506941T1 (de) | Behandlung psychiatrischer patienten mit schlafstörungen und/oder übermässiger tagesschläfrigkeit mit paliperidon | |
| BR112014011336A2 (pt) | composições farmacêuticas que compreendem 7-(1h-imidazol-4-ilmetil)-5,6,7,8-tetra-hidro-quinolina para tratamento de doenças e condições de pele | |
| WO2012038850A8 (en) | Pyrimidones for treatment of potassium channel related diseases | |
| HU0002154D0 (en) | Pharmaceutical compositions for treatment depression or symptoms concerning to depression | |
| RU2013139704A (ru) | Применение белка yb-1 и его фрагментов для изготовления лекарственных средств при лечении болезни альцгеймера | |
| AU2021225354B2 (en) | Composition for the prevention and treatment of dysbiosis | |
| CN104095787A (zh) | 一种薄荷味香水 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |