ATE472612T1 - Homogener lumineszenz-bioassay - Google Patents

Homogener lumineszenz-bioassay

Info

Publication number
ATE472612T1
ATE472612T1 AT06820060T AT06820060T ATE472612T1 AT E472612 T1 ATE472612 T1 AT E472612T1 AT 06820060 T AT06820060 T AT 06820060T AT 06820060 T AT06820060 T AT 06820060T AT E472612 T1 ATE472612 T1 AT E472612T1
Authority
AT
Austria
Prior art keywords
acceptor
donor
bioassay
energy transfer
fluorescent compound
Prior art date
Application number
AT06820060T
Other languages
English (en)
Inventor
Tero Soukka
Timo Oikari
Ville Haaslahti
Original Assignee
Hidex Oy
Turun Yliopisto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI20051204A external-priority patent/FI20051204A0/fi
Application filed by Hidex Oy, Turun Yliopisto filed Critical Hidex Oy
Application granted granted Critical
Publication of ATE472612T1 publication Critical patent/ATE472612T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
AT06820060T 2005-11-25 2006-11-17 Homogener lumineszenz-bioassay ATE472612T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73941105P 2005-11-25 2005-11-25
FI20051204A FI20051204A0 (fi) 2005-11-25 2005-11-25 Homogeeninen luminesenssibiomääritys
PCT/FI2006/000379 WO2007060280A1 (en) 2005-11-25 2006-11-17 Homogeneous luminescence bioassay

Publications (1)

Publication Number Publication Date
ATE472612T1 true ATE472612T1 (de) 2010-07-15

Family

ID=37806214

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06820060T ATE472612T1 (de) 2005-11-25 2006-11-17 Homogener lumineszenz-bioassay

Country Status (5)

Country Link
US (1) US7790392B2 (de)
EP (1) EP1957670B8 (de)
AT (1) ATE472612T1 (de)
DE (1) DE602006015227D1 (de)
WO (1) WO2007060280A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20070163A0 (fi) * 2007-02-27 2007-02-27 Hidex Oy Parannettu homogeeninen luminesenssibiotesti
CA2699612C (en) 2007-09-14 2013-01-08 Biosentinel, Llc Resonance energy transfer assay with cleavage sequence and spacer
EP3155406B1 (de) * 2014-06-12 2019-09-18 Voelcker, Nico Optischer biosensor
CN116413255A (zh) * 2018-07-18 2023-07-11 科美博阳诊断技术(上海)有限公司 一种均相化学发光检测试剂盒及其应用
DE102019219531A1 (de) * 2019-12-13 2021-06-17 Robert Bosch Gmbh Verfahren zur Durchführung einer Amplifikationsreaktion in einer mikrofluidischen Vorrichtung
EP3923035A1 (de) 2020-06-10 2021-12-15 Hidex Oy Verfahren zur bestimmung einer hintergrundzählrate in der flüssigszintillationszählung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998043072A1 (en) 1997-03-25 1998-10-01 Photonic Research Systems Limited Luminescence assays
US6768000B1 (en) * 1998-06-12 2004-07-27 Intergen Company Multi-fluorescent hairpin energy transfer oligonucleotides
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
US7098672B2 (en) * 2002-02-15 2006-08-29 Implant Sciences Corporation Flash vapor sampling for a trace chemical detector
JP4457001B2 (ja) * 2002-05-31 2010-04-28 セクレタリー・デパートメント・オブ・アトミック・エナジー ドナー／アクセプター部分が相補鎖上となる標的核酸検出のｍｅｔ／ｆｒｅｔに基づく方法
EP1608980B1 (de) * 2003-03-28 2007-08-15 SOUKKA, Tero Bioassay mit energietransfer mit homogener lumineszenz
US7619059B2 (en) * 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays

Also Published As

Publication number Publication date
US20090081662A1 (en) 2009-03-26
DE602006015227D1 (de) 2010-08-12
WO2007060280A1 (en) 2007-05-31
US7790392B2 (en) 2010-09-07
EP1957670A1 (de) 2008-08-20
EP1957670B1 (de) 2010-06-30
EP1957670B8 (de) 2010-08-25

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties