ATE460663T1 - Verfahren zum screening eines therapeutischen wirkstoffs für darmirritationssyndrome - Google Patents

Verfahren zum screening eines therapeutischen wirkstoffs für darmirritationssyndrome

Info

Publication number
ATE460663T1
ATE460663T1 AT06712387T AT06712387T ATE460663T1 AT E460663 T1 ATE460663 T1 AT E460663T1 AT 06712387 T AT06712387 T AT 06712387T AT 06712387 T AT06712387 T AT 06712387T AT E460663 T1 ATE460663 T1 AT E460663T1
Authority
AT
Austria
Prior art keywords
screening
active substance
therapeutic active
intestinal irritation
irritation syndrome
Prior art date
Application number
AT06712387T
Other languages
English (en)
Inventor
Toshiyuki Funatsu
Takuya Hirata
Yoshihiro Keto
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Application granted granted Critical
Publication of ATE460663T1 publication Critical patent/ATE460663T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT06712387T 2005-01-28 2006-01-26 Verfahren zum screening eines therapeutischen wirkstoffs für darmirritationssyndrome ATE460663T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005021151 2005-01-28
JP2006001205 2006-01-26

Publications (1)

Publication Number Publication Date
ATE460663T1 true ATE460663T1 (de) 2010-03-15

Family

ID=36740412

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06712387T ATE460663T1 (de) 2005-01-28 2006-01-26 Verfahren zum screening eines therapeutischen wirkstoffs für darmirritationssyndrome

Country Status (8)

Country Link
US (1) US20080010691A1 (de)
EP (1) EP1857816B1 (de)
JP (1) JP4725579B2 (de)
AT (1) ATE460663T1 (de)
CA (1) CA2596057A1 (de)
DE (1) DE602006012811D1 (de)
ES (1) ES2340195T3 (de)
WO (1) WO2006080385A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6444584B2 (ja) * 2013-03-25 2018-12-26 国立大学法人東京農工大学 飼育ネズミのストレス被曝判定方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4316793B2 (ja) * 1997-08-19 2009-08-19 三菱化学株式会社 過敏性腸症候群の治療剤
US20040034882A1 (en) * 1999-07-15 2004-02-19 Vale Wylie W. Corticotropin releasing factor receptor 2 deficient mice and uses thereof
RU2251838C2 (ru) * 1999-07-15 2005-05-20 Рисерч Дивелопмент Фаундейшн Способ получения неприродной трансгенной мыши с дефицитом гена рецептора 2 кортиколиберина и ее использование
AU2003241988A1 (en) * 2002-05-31 2003-12-19 Ajinomoto Co., Inc. Chronic stress-related disease model animal and method of constructing the same
EP1558081A4 (de) * 2003-01-13 2006-06-14 Dynogen Pharmaceuticals Inc Verfahren zur behandlung von funktionalen darmerkrankungen

Also Published As

Publication number Publication date
JP4725579B2 (ja) 2011-07-13
CA2596057A1 (en) 2006-08-03
DE602006012811D1 (de) 2010-04-22
EP1857816A4 (de) 2008-10-22
JPWO2006080385A1 (ja) 2008-06-19
ES2340195T3 (es) 2010-05-31
US20080010691A1 (en) 2008-01-10
EP1857816A1 (de) 2007-11-21
WO2006080385A1 (ja) 2006-08-03
EP1857816B1 (de) 2010-03-10

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Legal Events

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