ATE459711T1 - Erzeugung spezifischer adhäsion bei gram- negativen bakterien mittels verankerung von einzeldomänen aus immunglobulinen auf deren oberfläche mit autotransportern - Google Patents
Erzeugung spezifischer adhäsion bei gram- negativen bakterien mittels verankerung von einzeldomänen aus immunglobulinen auf deren oberfläche mit autotransporternInfo
- Publication number
- ATE459711T1 ATE459711T1 AT05706913T AT05706913T ATE459711T1 AT E459711 T1 ATE459711 T1 AT E459711T1 AT 05706913 T AT05706913 T AT 05706913T AT 05706913 T AT05706913 T AT 05706913T AT E459711 T1 ATE459711 T1 AT E459711T1
- Authority
- AT
- Austria
- Prior art keywords
- gram
- negative bacteria
- immunoglobulins
- generation
- specific adhesion
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title abstract 2
- 238000004873 anchoring Methods 0.000 title abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 title 1
- 102000018358 immunoglobulin Human genes 0.000 title 1
- 229940072221 immunoglobulins Drugs 0.000 title 1
- 108010073429 Type V Secretion Systems Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000010065 bacterial adhesion Effects 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1207—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200400073A ES2301262B1 (es) | 2004-01-14 | 2004-01-14 | Generacion de adhesion especifica en bacterias gram negativas mediante el anclaje de monodominos de inmunoglobulinas en su superficie con autotransportadores. |
| PCT/EP2005/000444 WO2005068619A1 (en) | 2004-01-14 | 2005-01-13 | Generation of specific adhesion in gram-negative bacteria by means of anchoring immunoglobulin single domains on their surface with autotransporters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE459711T1 true ATE459711T1 (de) | 2010-03-15 |
Family
ID=34778266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05706913T ATE459711T1 (de) | 2004-01-14 | 2005-01-13 | Erzeugung spezifischer adhäsion bei gram- negativen bakterien mittels verankerung von einzeldomänen aus immunglobulinen auf deren oberfläche mit autotransportern |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090155849A1 (de) |
| EP (1) | EP1709168B1 (de) |
| AT (1) | ATE459711T1 (de) |
| CA (1) | CA2553807A1 (de) |
| DE (1) | DE602005019691D1 (de) |
| ES (1) | ES2301262B1 (de) |
| WO (1) | WO2005068619A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010035702A1 (de) * | 2010-08-27 | 2012-03-01 | Zyrus Beteiligungsgesellschaft Mbh & Co. Patente I Kg | Ganzzell-Biokatalysator |
| CA2811699C (en) * | 2010-09-28 | 2019-07-02 | Abera Bioscience Ab | Fusion protein for secretory protein expression |
| CN103550789B (zh) * | 2013-11-25 | 2015-04-22 | 苏州大学 | 以减毒沙门氏菌为载体的口服肿瘤疫苗的制备及其应用 |
| WO2017186784A1 (en) * | 2016-04-26 | 2017-11-02 | Autodisplay Biotech Gmbh | Autodisplay of antibodies |
-
2004
- 2004-01-14 ES ES200400073A patent/ES2301262B1/es not_active Expired - Fee Related
-
2005
- 2005-01-13 DE DE602005019691T patent/DE602005019691D1/de active Active
- 2005-01-13 WO PCT/EP2005/000444 patent/WO2005068619A1/en active Application Filing
- 2005-01-13 CA CA002553807A patent/CA2553807A1/en not_active Abandoned
- 2005-01-13 US US10/586,245 patent/US20090155849A1/en not_active Abandoned
- 2005-01-13 AT AT05706913T patent/ATE459711T1/de not_active IP Right Cessation
- 2005-01-13 EP EP05706913A patent/EP1709168B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| US20090155849A1 (en) | 2009-06-18 |
| DE602005019691D1 (de) | 2010-04-15 |
| EP1709168A1 (de) | 2006-10-11 |
| CA2553807A1 (en) | 2005-07-28 |
| WO2005068619A1 (en) | 2005-07-28 |
| EP1709168B1 (de) | 2010-03-03 |
| ES2301262B1 (es) | 2009-05-29 |
| ES2301262A1 (es) | 2008-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |