ATE45288T1 - Radiodiagnostik-agens und seine herstellung. - Google Patents

Radiodiagnostik-agens und seine herstellung.

Info

Publication number
ATE45288T1
ATE45288T1 AT84104617T AT84104617T ATE45288T1 AT E45288 T1 ATE45288 T1 AT E45288T1 AT 84104617 T AT84104617 T AT 84104617T AT 84104617 T AT84104617 T AT 84104617T AT E45288 T1 ATE45288 T1 AT E45288T1
Authority
AT
Austria
Prior art keywords
radioactive
carrier
aqueous solution
manufacture
radiodiagnostic agent
Prior art date
Application number
AT84104617T
Other languages
German (de)
English (en)
Inventor
Keietsu Nihon Medi-P Takahashi
Azamasaki
Nobuo Ueda
Masaaki Hazue
Akira Yokoyama
Yoshior C O No Ginkakuj Ohmomo
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Application granted granted Critical
Publication of ATE45288T1 publication Critical patent/ATE45288T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT84104617T 1983-04-26 1984-04-25 Radiodiagnostik-agens und seine herstellung. ATE45288T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58073197A JPS59199636A (ja) 1983-04-26 1983-04-26 放射性診断剤
EP84104617A EP0123314B1 (en) 1983-04-26 1984-04-25 Radioactive diagnostic agent and its preparation

Publications (1)

Publication Number Publication Date
ATE45288T1 true ATE45288T1 (de) 1989-08-15

Family

ID=13511173

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84104617T ATE45288T1 (de) 1983-04-26 1984-04-25 Radiodiagnostik-agens und seine herstellung.

Country Status (8)

Country Link
US (1) US4645660A (enExample)
EP (1) EP0123314B1 (enExample)
JP (1) JPS59199636A (enExample)
KR (1) KR860001565B1 (enExample)
AT (1) ATE45288T1 (enExample)
AU (1) AU2727384A (enExample)
CA (1) CA1235063A (enExample)
DE (1) DE3479292D1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
US5393512A (en) * 1985-01-14 1995-02-28 Vanderheyden; Jean-Luc Stable therapeutic radionuclide compositions and methods for preparation thereof
EP0325559B1 (de) * 1988-01-20 1993-12-15 Ciba-Geigy Ag Verfahren zur Herstellung von Komplexverbindungen
US5011676A (en) * 1990-03-27 1991-04-30 Thomas Jefferson University Method to directly radiolabel antibodies for diagnostic imaging and therapy
JPH0477390U (enExample) * 1990-11-13 1992-07-06
JPH0491189U (enExample) * 1990-12-25 1992-08-07
DE69231469T2 (de) * 1991-08-29 2001-01-25 Mallinckrodt Medical, Inc. Verwendung von gentisinsäure oder gentisylalkohol zur stabilisierung von radio-markierten peptiden und proteinen
JP3051591B2 (ja) * 1993-03-05 2000-06-12 日本メジフィジックス株式会社 タリウム−２０１の容器に対する付着防止剤
GB9403855D0 (en) * 1994-03-01 1994-04-20 Scotia Holdings Plc Fatty acid derivatives
US6027710A (en) * 1996-09-18 2000-02-22 Nihon Medi-Physiscs Co., Ltd. Radiation-protecting agent
DK1585548T3 (en) * 2002-12-09 2018-09-03 Abraxis Bioscience Llc COMPOSITIONS AND PROCEDURES FOR THE DELIVERY OF PHARMACOLOGICAL AGENTS
KR20140148502A (ko) * 2002-12-09 2014-12-31 아브락시스 바이오사이언스, 엘엘씨 약리학적 물질의 조성물 및 그 전달방법
CN100418585C (zh) * 2003-07-24 2008-09-17 伯拉考成像股份公司 稳定的放射性药物组合物及制备方法
JP6415715B2 (ja) 2015-09-30 2018-10-31 デューク・ユニヴァーシティ アスコルベート製剤及び造影剤としての使用方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740418A (en) * 1970-07-01 1973-06-19 Squibb & Sons Inc Radioactive scanning preparation
US4364920A (en) * 1975-04-30 1982-12-21 Medi-Physics, Inc. Stable diagnostic reagents
JPS56125317A (en) * 1980-03-08 1981-10-01 Nippon Mejifuijitsukusu Kk Stable radioactive diagnosticum with radioactive metallic mark
JPS5750928A (en) * 1980-09-13 1982-03-25 Nippon Mejifuijitsukusu Kk Diagnostic agent for scanning bone
JPS57102820A (en) * 1980-12-19 1982-06-26 Nippon Mejifuijitsukusu Kk Agent for radiodiagnosis
EP0074429B1 (en) * 1981-09-16 1985-08-21 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic agent and its preparation
AT392004B (de) * 1981-10-27 1991-01-10 Hybritech Inc Verfahren zur herstellung eines monoklonalen antikoerpers gegen tumor-assoziiertes antigen und dessen verwendung
JPS5896031A (ja) * 1981-12-03 1983-06-07 Nippon Mejifuijitsukusu Kk 放射性診断剤およびその製造用組成物
US4455291A (en) * 1982-01-22 1984-06-19 New England Nuclear Corporation Accelerators for forming cationic technetium complexes useful as radiodiagnostic agents
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
ATE23800T1 (de) * 1982-06-10 1986-12-15 Mallinckrodt Inc Roentgen-sichtbarmachungsmittel.
EP0111414A3 (en) * 1982-12-08 1985-05-02 Mallinckrodt, Inc. (a Delaware corporation) Radiographic imaging agents
US4510125A (en) * 1982-12-08 1985-04-09 Mallinckrodt, Inc. Process for making lyophilized radiographic imaging kit

Also Published As

Publication number Publication date
KR860001565B1 (ko) 1986-10-08
DE3479292D1 (en) 1989-09-14
CA1235063A (en) 1988-04-12
EP0123314A2 (en) 1984-10-31
EP0123314A3 (en) 1986-12-30
JPS59199636A (ja) 1984-11-12
JPH0233692B2 (enExample) 1990-07-30
KR840008291A (ko) 1984-12-14
AU2727384A (en) 1984-11-01
EP0123314B1 (en) 1989-08-09
US4645660A (en) 1987-02-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee