ATE450618T1 - Zu lipidmembranen in archeabakterien analoge verbindungen und liposomale zusammensetzungen mit diesen verbindungen - Google Patents

Zu lipidmembranen in archeabakterien analoge verbindungen und liposomale zusammensetzungen mit diesen verbindungen

Info

Publication number
ATE450618T1
ATE450618T1 AT05850443T AT05850443T ATE450618T1 AT E450618 T1 ATE450618 T1 AT E450618T1 AT 05850443 T AT05850443 T AT 05850443T AT 05850443 T AT05850443 T AT 05850443T AT E450618 T1 ATE450618 T1 AT E450618T1
Authority
AT
Austria
Prior art keywords
compounds
nhc
archeabacteria
analogue
lipid membranes
Prior art date
Application number
AT05850443T
Other languages
English (en)
Inventor
Thierry Benvegnu
Daniel Plusquellec
Gildas Rethore
Mickaelle Sachet
Claude Ferec
Tristan Montier
Pascal Delepine
Pierre Lehn
Original Assignee
Enscr
Univ Bretagne Occidentale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enscr, Univ Bretagne Occidentale filed Critical Enscr
Application granted granted Critical
Publication of ATE450618T1 publication Critical patent/ATE450618T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04Saturated ethers
    • C07C43/13Saturated ethers containing hydroxy or O-metal groups
    • C07C43/135Saturated ethers containing hydroxy or O-metal groups having more than one ether bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/08Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/27Polyhydroxylic alcohols containing saturated rings
    • C07C31/272Monocyclic
    • C07C31/274Monocyclic with a three to five-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT05850443T 2004-12-07 2005-12-07 Zu lipidmembranen in archeabakterien analoge verbindungen und liposomale zusammensetzungen mit diesen verbindungen ATE450618T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0413028A FR2878846B1 (fr) 2004-12-07 2004-12-07 Composes analogues de lipides membranaires d'archaebacteries et compositions liposomiales integrant de tel composes
PCT/EP2005/056555 WO2006061396A1 (fr) 2004-12-07 2005-12-07 Composes analogues de lipides membranaires d'archaebacteries et compositions liposomiales integrant de tels composes

Publications (1)

Publication Number Publication Date
ATE450618T1 true ATE450618T1 (de) 2009-12-15

Family

ID=34953575

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05850443T ATE450618T1 (de) 2004-12-07 2005-12-07 Zu lipidmembranen in archeabakterien analoge verbindungen und liposomale zusammensetzungen mit diesen verbindungen

Country Status (7)

Country Link
US (1) US8088747B2 (de)
EP (1) EP1819824B1 (de)
AT (1) ATE450618T1 (de)
CA (1) CA2589688C (de)
DE (1) DE602005018100D1 (de)
FR (1) FR2878846B1 (de)
WO (1) WO2006061396A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
US8507277B2 (en) 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US20090208478A1 (en) * 2003-10-24 2009-08-20 Gencia Corporation Transducible polypeptides for modifying metabolism
WO2005056752A2 (en) 2003-10-24 2005-06-23 Gencia Corporation Methods and compositions for delivering polynucleotides
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
EP3166957B1 (de) 2014-07-11 2019-11-13 National Research Council of Canada Sulfatierte glycolipide als adjuvantien für impfstoffe
FR3052361B1 (fr) * 2016-06-09 2019-08-23 Centre National De La Recherche Scientifique Diethers d’archaea lipides synthetiques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000502087A (ja) * 1995-12-15 2000-02-22 ナショナル リサーチ カウンシル オブ カナダ アジュバンドおよび送達賦形剤としての、アーケオソーム類、補酵素q▲下10▼を含有するアーケオソーム類、および補酵素q▲下10▼を含有する他の種類のリポソーム類
AU4421200A (en) * 1999-04-26 2000-11-10 Celltech R & D Limited Bipolar lipids and their use for the delivery of bioactive substances

Also Published As

Publication number Publication date
EP1819824B1 (de) 2009-12-02
US8088747B2 (en) 2012-01-03
DE602005018100D1 (de) 2010-01-14
CA2589688A1 (en) 2006-06-15
US20090232880A1 (en) 2009-09-17
EP1819824A1 (de) 2007-08-22
CA2589688C (en) 2018-05-22
FR2878846A1 (fr) 2006-06-09
WO2006061396A1 (fr) 2006-06-15
FR2878846B1 (fr) 2007-02-23

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